Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Du N'Guyen"'
Autor:
Etienne Dague, Véronique Pons, Alexandre Roland, Jean-Marc Azaïs, Silvia Arcucci, Véronique Lachaize, Samuel Velmont, Emmanuelle Trevisiol, Du N’Guyen, Jean-Michel Sénard, Céline Galés
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Atomic force microscopy-based single molecule force spectroscopy reveals the unfolding of G-protein coupled receptors on the surface of living mammalian cells.
Externí odkaz:
https://doaj.org/article/67f6e8d7ba7549038bda4fd59c9c2b69
Autor:
Marc Kermorgant, Pierre-Olivier Fernagut, Wassilios G. Meissner, Dina N. Arvanitis, Du N'Guyen, Jean-Michel Senard, Anne Pavy-Le Traon
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Multiple system atrophy (MSA) is a rare and progressive neurodegenerative disorder. Autonomic failure (AF) is one main clinical feature which has a significant impact on health-related quality of life. The neuropathological hallmark of MSA is the abn
Externí odkaz:
https://doaj.org/article/12270e49d871457b953e494d3c20e6ce
Autor:
Lauriane Onfroy, Ségolène Galandrin, Stéphanie M. Pontier, Marie-Hélène Seguelas, Du N’Guyen, Jean-Michel Sénard, Céline Galés
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Biased agonism at G protein coupled receptors emerges as an opportunity for development of drugs with enhanced benefit/risk balance making biased ligand identification a priority. However, ligand biased signature, classically inferred from l
Externí odkaz:
https://doaj.org/article/46b62063d1b048b08dc910da43acf68d
Akademický článek
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Autor:
Etienne Dague, Véronique Pons, Alexandre Roland, Jean-Marc Azaïs, Silvia Arcucci, Véronique Lachaize, Samuel Velmont, Emmanuelle Trevisiol, Du N’Guyen, Jean-Michel Sénard, Céline Galés
Publikováno v:
Communications Biology
Communications Biology, 2022, 5 (1), ⟨10.1038/s42003-022-03162-w⟩
Communications Biology, 2022, 5 (1), ⟨10.1038/s42003-022-03162-w⟩
International audience; G protein-coupled receptors (GPCRs) form the largest family of cell surface receptors. Despite considerable insights into their pharmacology, the GPCR architecture at the cell surface still remains largely unexplored. Herein,
Autor:
Cédric Garcia, Véronique Pons, Du N’Guyen, Laurent O. Martinez, Bernard Payrastre, Céline Galés, Jean-Michel Senard, Agnès Maurel-Ribes, Michel Nauze
Publikováno v:
Cellular and Molecular Life Sciences. 76:561-576
P2Y12 receptor (P2Y12-R) is one of the major targets for drug inhibiting platelet aggregation in the treatment/prevention of arterial thrombosis. However, the clinical use of P2Y12-R antagonists faces some limitations, such as a delayed onset of acti
Autor:
Jean-Michel Senard, Marie-Hélène Seguelas, Du N’Guyen, Caroline Dubroca, Jean-Louis Banères, Céline M'Kadmi, Yvan Nicaise, Céline Galés, Atul Pathak, Cédric Boularan, Colette Denis, Claire Pilette, Ségolène Galandrin, Jacky Marie
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 68(6)
Hyperactivity of the renin–angiotensin–aldosterone system through the angiotensin II (Ang II)/Ang II type 1 receptor (AT1-R) axis constitutes a hallmark of hypertension. Recent findings indicate that only a subset of AT1-R signaling pathways is c
Akademický článek
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Autor:
Céline Galés, Du N’Guyen, Célie Mias-Vigouroux, Fanny Leboulanger, Céline Guilbeau-Frugier, Jean-Michel Senard, Marie-Hélène Seguelas
Publikováno v:
Archives of Cardiovascular Diseases Supplements. (2):138
Background/ObjectiveDespite piceatannol is a polyphenol belonging the stilbene family as resveratrol, only very scarce studies have adressed its effects in obesity. Thus, our objective was to analyze the potential effects of piceatannol on cardiac ti