Zobrazeno 1 - 10
of 3 095
pro vyhledávání: '"Drzezga, A."'
Autor:
Doering, Elena, Hönig, Merle C., Deußer, Tobias, Bischof, Gerard N., van Eimeren, Thilo, Drzezga, Alexander, Ellingsen, Lotta M.
Publikováno v:
Medical Imaging 2024: Clinical and Biomedical Imaging
Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to cognitive decline. [$^{18}$F]-Fluorodeoxyglucose positron emission tomography ([$^{18}$F]-FDG PET) is used to monitor brain metabolism, aiding in the diagnosis and assess
Externí odkaz:
http://arxiv.org/abs/2402.04299
Autor:
Verena Dzialas, Merle C. Hoenig, Stéphane Prange, Gérard N. Bischof, the Parkinson’s Progression Marker Initiative, Alexander Drzezga, Thilo van Eimeren
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Resilience in neuroscience generally refers to an individual’s capacity to counteract the adverse effects of a neuropathological condition. While resilience mechanisms in Alzheimer’s disease are well-investigated, knowledge regarding its
Externí odkaz:
https://doaj.org/article/6670e329cb2c466388f32386778e75eb
Autor:
Simone Wegen, Karina Claus, Philipp Linde, Johannes Rosenbrock, Maike Trommer, Thomas Zander, Armin Tuchscherer, Christiane Bruns, Hans Anton Schlößer, Wolfgang Schröder, Marie-Lisa Eich, Thomas Fischer, Klaus Schomäcker, Alexander Drzezga, Carsten Kobe, Katrin Sabine Roth, Jasmin Josefine Weindler
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Fibroblast activation protein (FAP) is expressed in the tumor microenvironment (TME) of various cancers. In our analysis, we describe the impact of dual-tracer imaging with Gallium-68-radiolabeled inhibitors of FAP (FAPI-46-PET/CT
Externí odkaz:
https://doaj.org/article/ce5d14ae5759413998c9bebf6d8a92b5
Autor:
Ali Gordji-Nejad, Andreas Matusch, Sophie Kleedörfer, Harshal Jayeshkumar Patel, Alexander Drzezga, David Elmenhorst, Ferdinand Binkofski, Andreas Bauer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The inverse effects of creatine supplementation and sleep deprivation on high energy phosphates, neural creatine, and cognitive performances suggest that creatine is a suitable candidate for reducing the negative effects of sleep deprivation
Externí odkaz:
https://doaj.org/article/17bf3082cd834a9b89ddb6889866f279
Autor:
Hendrik Theis, Stéphane Prange, Gérard N. Bischof, Merle C. Hoenig, Marc Tittgemeyer, Lars Timmermann, Gereon R. Fink, Alexander Drzezga, Carsten Eggers, Thilo van Eimeren
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Impulsive-compulsive behaviour (ICB) is a frequently observed non-motor symptom in early Parkinson’s disease after initiating dopamine replacement therapy. At the opposite end of the motivated behaviour spectrum, apathy occurs in early Par
Externí odkaz:
https://doaj.org/article/d8b9f2365bfd433eb5435de244ce6a9f
Autor:
Thomas Fischer, Christopher Dietrich, Felix Dietlein, Sergio Muñoz Vázquez, Beate Zimmermanns, Philipp Krapf, Ferdinand Sudbrock, Alexander Drzezga, Markus Dietlein, Klaus Schomäcker
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10638 (2024)
This study evaluates the efficacy of [131I]I-ERIC1 in targeting and inhibiting the growth of SCLC tumors in mice, focusing on tumor accumulation and regression and potential side effects. NCAM-positive NCI-H69 SCLC cells were implanted in CB 17 SCID
Externí odkaz:
https://doaj.org/article/c159e8a26cf847cebf574b57998110c9
Autor:
Thomas Fischer, Felix Dietlein, Detlev Bongartz, Martin Klehr, Beate Zimmermanns, Matthias Schmidt, Angela Mohr, Fabian Mohr, Ferdinand Sudbrock, Philipp Krapf, Alexander Drzezga, Markus Dietlein, Klaus Schomäcker
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10737 (2024)
Preliminary studies on a radioactive antibody against the neural cell adhesion molecule (NCAM) demonstrated a significant accumulation of [131I]I-ERIC1 in neuroblastoma tumor cells in mice. This study aims to validate the therapeutic efficacy and pot
Externí odkaz:
https://doaj.org/article/b91729d3204143fb817347f7a35074c6
Autor:
Heike Endepols, Nadine Apetz, Lukas Vieth, Christoph Lesser, Léon Schulte-Holtey, Bernd Neumaier, Alexander Drzezga
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8617 (2024)
Compensatory changes in brain connectivity keep motor symptoms mild in prodromal Parkinson’s disease. Studying compensation in patients is hampered by the steady progression of the disease and a lack of individual baseline controls. Furthermore, co
Externí odkaz:
https://doaj.org/article/a8a0d3e4d18f492392e6d24ca344c228
Autor:
Beer, Simone, Elmenhorst, David, Bischof, Gerard N., Ramirez, Alfredo, Bauer, Andreas, Drzezga, Alexander
Publikováno v:
In Neurobiology of Aging November 2024 143:19-29
Autor:
Marina C. Ruppert-Junck, Gunter Kräling, Andrea Greuel, Marc Tittgemeyer, Lars Timmermann, Alexander Drzezga, Carsten Eggers, David Pedrosa
Publikováno v:
Frontiers in Computational Neuroscience, Vol 18 (2024)
Parkinson's disease (PD) is currently diagnosed largely on the basis of expert judgement with neuroimaging serving only as a supportive tool. In a recent study, we identified a hypometabolic midbrain cluster, which includes parts of the substantia ni
Externí odkaz:
https://doaj.org/article/70efd511948d4301be4f0e0c5c3243de