Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Drummond H. Bowden"'
Autor:
Drummond H. Bowden
Publikováno v:
Models of Lung Disease ISBN: 9781003066248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5258d02fd88e80073c2b263e60040255
https://doi.org/10.1201/9781003066248-22
https://doi.org/10.1201/9781003066248-22
Publikováno v:
Experimental Lung Research. 20:251-262
Severe alveolar epithelial injury disrupts the normal epithelial cell-fibroblast relationship, leading to abnormal repair and the uncontrolled growth of fibroblasts. It is postulated that selective inhibition of fibroblasts growth after injury may al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fed0463863b9b130b8945cf644a3bf9
https://doi.org/10.3109/01902149409064386
https://doi.org/10.3109/01902149409064386
Autor:
Ian Y. R. Adamson, Drummond H. Bowden
Publikováno v:
Respiratory System ISBN: 9783642646676
The experiments described here were designed to study the interactions of macrophages and fibroblasts during the development of pulmonary fibrosis following a single intratracheal injection of 2 mg crystalline silica (particle diameter 0.3 µm), or 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::417beca16850ad2b66804d84a7fe96ac
https://doi.org/10.1007/978-3-642-61042-4_27
https://doi.org/10.1007/978-3-642-61042-4_27
Autor:
Drummond H. Bowden
Publikováno v:
Respiratory System ISBN: 9783642646676
The gross appearance does not distinguish developing and established fibrotic lesions induced by bleomycin from injury caused by drugs or other chemicals. After a single intravenous dose fibrosis is multifocal, rarely confluent; diffuse lobular and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1652df6065e2d1d24e386158a25d372e
https://doi.org/10.1007/978-3-642-61042-4_25
https://doi.org/10.1007/978-3-642-61042-4_25
Autor:
Ian Y. R. Adamson, Drummond H. Bowden
Publikováno v:
Respiratory System ISBN: 9783642646676
Acute Hyperoxia. If adult mice are exposed to 90% oxygen for 6 days, either they die or, on return to air, they make a complete recovery with no sequelae. In those that die the lungs are hemorrhagic, solid, and airless (Adamson and Bowden 1974).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf6e6d85e9f31a6d7eb38c86a1091be
https://doi.org/10.1007/978-3-642-61042-4_26
https://doi.org/10.1007/978-3-642-61042-4_26
Publikováno v:
Experimental lung research. 20(3)
It has been suggested that increased recruitment of phagocytes and subsequent clearance of particles may follow instillation of a leukocyte chemoattractant to lungs containing silica. The present study quantitated serially the silica content in alveo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4447bc98f905e4984afbf443fe1b5fa
https://pubmed.ncbi.nlm.nih.gov/7925140
https://pubmed.ncbi.nlm.nih.gov/7925140
Autor:
Drummond H. Bowden
Publikováno v:
Environmental Health Perspectives
An overview of the pulmonary macrophage is provided, with particular emphasis on the origin of this cell and the adaptive mechanisms whereby the macrophagic system is able to respond to increased inhalant loads of organic and inorganic pollutants. Ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1584352ae74a4c2d49b51134c5a5d8
https://doi.org/10.1289/ehp.761655
https://doi.org/10.1289/ehp.761655
Publikováno v:
The Journal of Pathology. 158:73-80
Macrophage-derived products have been implicated in fibroblast stimulation following particle deposition in the lung. To assess the role of macrophages in the alveolus versus those in the interstitium in the induction of pulmonary fibrosis, we compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fd944a8b650f45abda2de349063cee
https://doi.org/10.1002/path.1711580114
https://doi.org/10.1002/path.1711580114
Autor:
Drummond H. Bowden
Publikováno v:
Environmental Health Perspectives
The pulmonary macrophagic system is critical to the defense of the lung, keeping the alveoli clean and sterile and responding on demand with an adaptive outpouring of new cells into the air sacs. Under basal conditions alveolar macrophages, in common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a1e00224668802cea19ab368872275
https://doi.org/10.1289/ehp.8455327
https://doi.org/10.1289/ehp.8455327
Publikováno v:
Experimental Lung Research. 14:781-796
The pulmonary response was investigated during the early lymphoproliferative phase of an acute graft-versus-host (GVH) reaction induced in (C57BL/6 x A/J)F1 hybrid mice by iv injection of 50 x 10(6) A/J spleen and lymph node cells. The GVH reaction w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfc9cfcd0aea438e16596ab7799a865
https://doi.org/10.3109/01902148809087844
https://doi.org/10.3109/01902148809087844