Zobrazeno 1 - 10
of 1 064
pro vyhledávání: '"DrugBank"'
Autor:
Fateme Yazdani, Negar Mottaghi-Dastjerdi, Behzad Shahbazi, Khadijeh Ahmadi, Abozar Ghorbani, Mohammad Soltany-Rezaee-Rad, Hamed Montazeri, Farzane Khoshdel, Pietro Hiram Guzzi
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37451- (2024)
Introduction: Esophageal Cancer (EC) ranks among the most common malignancies worldwide. Most EC patients acquire drug resistance to chemotherapy either intrinsically or acquired after T-DM1 treatment, which shows that increasing or decreasing the ex
Externí odkaz:
https://doaj.org/article/d215ae60545a489d91b29722cabbf741
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 6, Iss , Pp 100115- (2024)
The drug development process is costly and time-consuming. Repurposing existing approved drugs, an efficient and cost-effective strategy, involves assessing numerous drug-protein pairs to uncover new interactions. While modern in silico methods enhan
Externí odkaz:
https://doaj.org/article/08cc79105f91450aa2fc2b137585548c
Autor:
Eugenia D. Namiot, Diana Smirnovová, Aleksandr V. Sokolov, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Clinical trials are the gold standard for testing new therapies. Databases like ClinicalTrials.gov provide access to trial information, mainly covering the US and Europe. In 2006, WHO introduced the global ICTRP, aggregating data from C
Externí odkaz:
https://doaj.org/article/ac2e9c102ff742b58fa25e0186c1c5c8
Autor:
Sidra Abbas, Gabriel Avelino Sampedro, Mideth Abisado, Ahmad S. Almadhor, Tai-Hoon Kim, Monji Mohamed Zaidi
Publikováno v:
IEEE Access, Vol 11, Pp 101525-101536 (2023)
Drug-drug interaction (DDI) is a significant public health issue that accounts for 30% of unanticipated clinically hazardous medication events. The past decade has seen an evolution in informatics-based research for DDI signal identification. This pa
Externí odkaz:
https://doaj.org/article/2bea1edb2afc4a13a2c9dac153d2fe31
Autor:
Dewi Saputri, Zaki Mubarak, Mudatsir Mudatsir, Inda Setyawati, Aprijal Ghiyas Setiawan, Mahdi Abrar
Publikováno v:
Journal of Advanced Pharmaceutical Technology & Research, Vol 14, Iss 3, Pp 196-201 (2023)
Fusobacterium nucleatum is a Gram-negative anaerobic bacteria that is commonly found in oral cavities and is associated with connective tissue destruction in periodontitis. UDP-N-acetylglucosamine 1-carboxyltransferase with enzyme commission number 2
Externí odkaz:
https://doaj.org/article/49636b82577f4eafb133ce0452856c8a
Autor:
Emanuela Marchese, Maria Eugenia Gallo Cantafio, Francesca Alessandra Ambrosio, Roberta Torcasio, Ilenia Valentino, Francesco Trapasso, Giuseppe Viglietto, Stefano Alcaro, Giosuè Costa, Nicola Amodio
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1712 (2023)
Polyphenols, an important class of natural products, are widely distributed in plant-based foods. These compounds are endowed with several biological activities and exert protective effects in various physiopathological contexts, including cancer. We
Externí odkaz:
https://doaj.org/article/cbf9fba7f0924ccab0a73e16ac2b47ab
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Environment International, Vol 170, Iss , Pp 107625- (2022)
Bioconcentration factors (BCFs) are markers of chemical substance accumulation in organisms, and they play a significant role in determining the environmental risk of various chemicals. Experiments to obtain BCFs are expensive and time-consuming; the
Externí odkaz:
https://doaj.org/article/0113f6e6bbcc47259914cb3cf4deb917