Zobrazeno 1 - 10
of 8 909
pro vyhledávání: '"Drug-related toxicity"'
Publikováno v:
Journal of Pediatric Research, Vol 9, Iss 1, Pp 60-65 (2022)
Aim:Thiopurine S-methyltransferase (TPMT) is an essential enzyme in the metabolism of thiopurine drugs, and its activity may change due to different polymorphisms in the TPMT gene. The TPMT gene has different genetic polymorphisms in different ethnic
Externí odkaz:
https://doaj.org/article/517b2d1e68174667882d67c0e5c6ff96
Autor:
Ataseven, Eda1 eda.ataseven@ege.edu.tr, Kosova, Buket2, Aktan, Çağdaş3, Kurugöl, Zafer4, Kantar, Mehmet1
Publikováno v:
Journal of Pediatric Research. Mar2022, Vol. 9 Issue 1, p60-65. 6p.
Akademický článek
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Akademický článek
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Autor:
Doreen Z. Mhandire, Andrew K. L. Goey
Publikováno v:
Mol Diagn Ther
Many anticancer drugs cause adverse drug reactions (ADRs) that negatively impact safety and reduce quality of life. The typical narrow therapeutic range and exposure-response relationships described for anticancer drugs make precision dosing critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20a0f236cbd9ae631e7efe9d20cb368
https://doi.org/10.1007/s40291-021-00575-x
https://doi.org/10.1007/s40291-021-00575-x
Autor:
Tetsuya Ito, Yasuhiro Maeda, Takema Kato, Tetsushi Yoshikawa, Takuma Ishihara, Yoko Nakajima, Hiroki Kurahashi, Hiroshi Matsuoka, Koji Masumori, Hidetoshi Katsuno, Kenji Kawada, Yasuko Shinkai, Katsuyuki Yokoi
Publikováno v:
Cancer Science
Cancer treatment with a fluoropyrimidine (FP) is often accompanied by severe toxicity that may be dependent on the activity of catalytic enzymes encoded by the DPYD, DPYS, and UPB1 genes. Genotype‐guided dose individualization of FP therapy has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b43d3811436a540f076dbd70495ab8
http://europepmc.org/articles/PMC7469832
http://europepmc.org/articles/PMC7469832
Autor:
Smith, T.J. *, Coyne, P.J., Staats, P.S., Deer, T., Stearns, L.J., Rauck, R.L., Boortz-Marx, R.L., Buchser, E., Català, E., Bryce, D.A., Cousins, M., Pool, G.E.
Publikováno v:
In Annals of Oncology May 2005 16(5):825-833
Autor:
Bongiovanni, Marco *, Cicconi, Paola, Landonio, Simona, Meraviglia, Paola, Testa, Letizia, Di Biagio, Antonio, Chiesa, Elisabetta, Tordato, Federica, Bini, Teresa, Monforte, Antonella d’Arminio
Publikováno v:
In International Journal of Antimicrobial Agents 2005 26(1):88-91
Autor:
Chaplin, Martha
Background In pharmacogenetic studies, researchers explore how genetic variants impact individuals��� responses to drugs. Implementation of pharmacogenetic tests in clinical practice can improve treatment efficacy and reduce toxicity. For healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585b5876a70b9322ec681b19de3615cf
Autor:
M. van Zeller, C. Damas
Publikováno v:
Revista Portuguesa de Pneumologia (English Edition), Vol 21, Iss 1, Pp 45- (2015)
Externí odkaz:
https://doaj.org/article/7bed1c66ac8c40f7aa426f7792c2694d