Zobrazeno 1 - 10 of 55 pro vyhledávání: '"Drug-metabolizing enzymes (DMEs)"'
1
Akademický článek
Optical substrates for drug-metabolizing enzymes: Recent advances and future perspectives
Autor: Qiang Jin, JingJing Wu, Yue Wu, Hongxin Li, Moshe Finel, Dandan Wang, Guangbo Ge
Publikováno v: Acta Pharmaceutica Sinica B, Vol 12, Iss 3, Pp 1068-1099 (2022)
Drug-metabolizing enzymes (DMEs), a diverse group of enzymes responsible for the metabolic elimination of drugs and other xenobiotics, have been recognized as the critical determinants to drug safety and efficacy. Deciphering and understanding the ke
Externí odkaz: https://doaj.org/article/26af5e5a95de47ab88ef509d59f2b96f
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2
Akademický článek
The Central Role of Cytochrome P450 in Xenobiotic Metabolism—A Brief Review on a Fascinating Enzyme Family
Autor: Francisco Esteves, José Rueff, Michel Kranendonk
Publikováno v: Journal of Xenobiotics, Vol 11, Iss 3, Pp 94-114 (2021)
Human Cytochrome P450 (CYP) enzymes constitute a superfamily of membrane-bound hemoproteins that are responsible for the metabolism of a wide variety of clinically, physiologically, and toxicologically important compounds. These heme-thiolate monooxy
Externí odkaz: https://doaj.org/article/f62a7b0591ab4024b2099490050f7ec1
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3
Akademický článek
Distribution of the Most Common Genetic Variants Associated with a Variable Drug Response in the Population of the Republic of Macedonia
Autor: Nestorovska Kapedanovska A., Jakovski K., Naumovska Z., Bajro Hiljadnikova M., Sterjev Z., Eftimov A., Geskovska Matevska N., Suturkova L., Dimitrovski K., Labacevski N., Dimovski A. J.
Publikováno v: Balkan Journal of Medical Genetics, Vol 17, Iss 2, Pp 5-14 (2014)
Genetic variation in the regulation, expression and activity of genes coding for Phase I, Phase II drug metabolizing enzymes (DMEs) and drug targets, can be defining factors for the variability in both the effectiveness and occurrence of drug therapy
Externí odkaz: https://doaj.org/article/633d2bff21fb41b298cc9b4a3b8de63f
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4
Optical substrates for drug-metabolizing enzymes : Recent advances and future perspectives
Autor: Jin, Qiang, Wu, JingJing, Wu, Yue, Li, Hongxin, Finel, Moshe, Wang, Dandan, Ge, Guangbo
Drug-metabolizing enzymes (DMEs), a diverse group of enzymes responsible for the metabolic elimination of drugs and other xenobiotics, have been recognized as the critical determinants to drug safety and efficacy. Deciphering and understanding the ke
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1593::7bf333ae1a9ec52fc55113b085f13304
http://hdl.handle.net/10138/343340
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5
Akademický článek
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6
The Central Role of Cytochrome P450 in Xenobiotic Metabolism—A Brief Review on a Fascinating Enzyme Family
Autor: Francisco de Assis Esteves, José Rueff, Michel Kranendonk
Publikováno v: Journal of Xenobiotics, Vol 11, Iss 7, Pp 94-114 (2021)
Journal of Xenobiotics
Human Cytochrome P450 (CYP) enzymes constitute a superfamily of membrane-bound hemoproteins that are responsible for the metabolism of a wide variety of clinically, physiologically, and toxicologically important compounds. These heme-thiolate monooxy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9902e554c3b245e6875a11b99bc8507
https://hdl.handle.net/10362/120545
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7
Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway
Autor: Boyu Tan, Lei Zhang, Mingming Li, Hongyan Wei, Feng Xu, Zhijun Xiao, Ting Zhou
Publikováno v: Oncotarget
// Hongyan Wei 1, 2, * , Ting Zhou 1, * , Boyu Tan 2 , Lei Zhang 3 , Mingming Li 1 , Zhijun Xiao 1 and Feng Xu 1, 3 1 Fengxian Hospital, Southern Medical University, Shanghai, China 2 Hunan Provincial People’s Hospital, Hunan Normal University, Cha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24637a7e672a8116533415d3290a32f9
http://europepmc.org/articles/PMC5546485
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8
Distribution of the Most Common Genetic Variants Associated with a Variable Drug Response in the Population of the Republic of Macedonia
Autor: Hiljadnikova M. Bajro, Krume Jakovski, K. Dimitrovski, Zorica Naumovska, Nikola Labacevski, Matevska N. Geskovska, Aleksandar Eftimov, Zoran Sterjev, Ljubica Suturkova, Kapedanovska A. Nestorovska, Aleksandar Dimovski
Publikováno v: Balkan Journal of Medical Genetics, Vol 17, Iss 2, Pp 5-14 (2014)
Balkan Journal of Medical Genetics
Genetic variation in the regulation, expression and activity of genes coding for Phase I, Phase II drug metabolizing enzymes (DMEs) and drug targets, can be defining factors for the variability in both the effectiveness and occurrence of drug therapy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2e139f5bb3dec7b8266e214dbc1e4e
https://doi.org/10.2478/bjmg-2014-0069
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9
Akademický článek
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10
Akademický článek
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