Zobrazeno 1 - 10
of 775
pro vyhledávání: '"Drug-disease"'
Publikováno v:
Complex & Intelligent Systems, Vol 11, Iss 1, Pp 1-14 (2024)
Abstract Drug repositioning, the discovery of new therapeutic uses for existing drugs, is increasingly gaining attention as a cost-effective and high-yield drug discovery strategy. Existing methods integrate diverse biological information into hetero
Externí odkaz:
https://doaj.org/article/d6ec045d8d14444992511fa7a1f06141
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Motivation Computational techniques for drug-disease prediction are essential in enhancing drug discovery and repositioning. While many methods utilize multimodal networks from various biological databases, few integrate comprehensive multi-
Externí odkaz:
https://doaj.org/article/d6551e4582384ec6bf08a983ed7fe1bc
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Conducting traditional wet experiments to guide drug development is an expensive, time-consuming and risky process. Analyzing drug function and repositioning plays a key role in identifying new therapeutic potential of approved dr
Externí odkaz:
https://doaj.org/article/6f22110af321478f8be2cb5e6eae81e8
Publikováno v:
In Intelligence-Based Medicine 2025 11
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Identification of potential drug–disease associations is important for both the discovery of new indications for drugs and for the reduction of unknown adverse drug reactions. Exploring the potential links between drugs and dise
Externí odkaz:
https://doaj.org/article/7fd20ccd36d246e09e6c032fe82c10de
Autor:
Kübra Özokcu, Maaike M. E. Diesveld, Suzan G. H. Gipmans, Laura E. J. Peeters, Bert-Jan van den Born, Sander D. Borgsteede
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background:Hypertension, a significant risk factor for cardiovascular diseases, demands proactive management as cardiovascular diseases remain the leading cause of death worldwide. Reducing systolic and diastolic blood pressure levels below recommend
Externí odkaz:
https://doaj.org/article/876fdfffad454550801f7caa916e0231
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Accurately identifying novel indications for drugs is crucial in drug research and discovery. Traditional drug discovery is costly and time-consuming. Computational drug repositioning can provide an effective strategy for discovering potential drug-d
Externí odkaz:
https://doaj.org/article/1bf5fe6e14924dfe89a38e36bf98e381
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 8, Pp 14136-14157 (2023)
Drugs, which treat various diseases, are essential for human health. However, developing new drugs is quite laborious, time-consuming, and expensive. Although investments into drug development have greatly increased over the years, the number of drug
Externí odkaz:
https://doaj.org/article/0e0d9514e78e45f2a96c61cd6ea66156
Autor:
Xianbin Li, Minzhen Liao, Bing Wang, Xiangzhen Zan, Yanhao Huo, Yue Liu, Zhenshen Bao, Peng Xu, Wenbin Liu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4446-4455 (2023)
Numerous computational drug repurposing methods have emerged as efficient alternatives to costly and time-consuming traditional drug discovery approaches. Some of these methods are based on the assumption that the candidate drug should have a reversa
Externí odkaz:
https://doaj.org/article/92d29c109e874640ad6beafdff8b77b6
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Associations of drugs with diseases provide important information for expediting drug development. Due to the number of known drug-disease associations is still insufficient, and considering that inferring associations between the
Externí odkaz:
https://doaj.org/article/e106b9cb407142eeaf61450b7188be6d