Zobrazeno 1 - 10 of 221 pro vyhledávání: '"Drug-discovering"'
1
Akademický článek
Descubrimiento de fármacos basado en cribado virtual refinado con enfoques neuronales paralelos
Autor: Pérez-Sánchez, H., Cano, G., García-Rodríguez, J., Cecilia, J.M.
Publikováno v: In Revista Internacional de Métodos Numéricos para Cálculo y Diseño en Ingeniería October-December 2015 31(4):207-211
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2
Akademický článek
A dual-labeling molecule for efficient drug discovery of mitochondrial-lysosomal interactions
Autor: Jinfang Wu, Xiaolei Wang, Xiang Li, Zixuan Zhu, Zhongcheng Cui, Tao Zhang, Weiwei Zou, Guanying Han
Publikováno v: Molecular and Cellular Probes, Vol 76, Iss , Pp 101968- (2024)
The close association between organelle interactions, such as mitochondrial–lysosomal interactions, and various diseases, including tumors, remains a challenge for drug discovering and identification. Conventional evaluation methods are often compl
Externí odkaz: https://doaj.org/article/1ec6339cbfcd416c9eedb9b00bedc1ba
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3
Akademický článek
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4
Akademický článek
Activation of NF-κ B signalling pathway by inflammatory regulators and associated drug discovering.
Autor: ShiQin Xu1, XiaoHong Li1, XiaoFeng Shen1, XiRong Guo2, YuZhu Peng2, YuSheng Liu1, QingSong Zhao1, ShanWu Feng1, FuZhou Wang1 zfwang50@njmu.edu.cn
Publikováno v: Internet Journal of Medical Update. Jul2010, Vol. 5 Issue 2, p38-44. 7p. 1 Diagram.
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5
Activation of NF-κ B signaling pathway by inflammatory regulators and associated drug discovering
Autor: Dr. ShiQin Xu, Dr. XiaoHong Li, Prof. XiaoFeng Shen, Prof. XiRong Guo, Prof. YuZhu Peng, Dr. YuSheng Liu, Dr. QingSong Zhao, Dr. ShanWu Feng, Dr. FuZhou Wang
Publikováno v: Internet Journal of Medical Update, Vol 5, Iss 2, Pp 38-44 (2010)
Intracellular signalling transduction plays a pivotal role in cell activation, and the regulation of gene transcription needs the involvement of series of nuclear factors. Nuclear transcription factor- kappa B, one of the key factors in mediating gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::8fba315b486fce9613a3c6ed3235ce2f
http://www.akspublication.com/Paper08_Jul2010_.pdf
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6
Virtual screening refined with parallel neural approaches improves drug discovering
Autor: Horacio Pérez-Sánchez, Gaspar Cano, José M. Cecilia, Jose Garcia-Rodriguez
Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
En el campo de la medicina clínica es crucial poder determinar la seguridad y la eficacia de los fármacos actuales y además acelerar el descubrimiento de nuevos compuestos activos. Para ello se llevan a cabo ensayos de laboratorio, que son método
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2525daa904197e4ae61ae53e2d2da5
https://hdl.handle.net/10045/53498
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7
Akademický článek
In silico design and pharmacokinetics investigation of some novel hepatitis C virus NS5B inhibitors: pharmacoinformatics approach
Autor: Stephen Ejeh, Adamu Uzairu, Gideon A. Shallangwa, Stephen E. Abechi, Muhammad Tukur Ibrahim
Publikováno v: Bulletin of the National Research Centre, Vol 46, Iss 1, Pp 1-11 (2022)
Abstract Background Hepatitis C virus (HCV) is a contagious disease that damages the liver over time, eventually leading to cirrhosis and death. Chronic HCV infection is regarded as a serious health problem worldwide, impacting up to 3% of the popula
Externí odkaz: https://doaj.org/article/48506a6fe2a549ce9007fea1ec75e792
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8
Akademický článek
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9
Activation of NF-ê B signalling pathway by inflammatory regulators and associated drug discovering
Autor: S Xu, X Li, X Shen, X Guo, Y Peng, Y Liu, Q Zhao, S Feng, F Wang
Publikováno v: Internet Journal of Medical Update-EJOURNAL; Vol 6, No 2 (2011)
Intracellular signalling transduction plays a pivotal role in cell activation,and the regulation of gene transcription needs the involvement of series of nuclear factors. Nuclear transcription factor- kappa B, one of the key factors in mediating gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a927597fe04880ef30d6462664a3b1a
https://www.ajol.info/index.php/ijmu/article/view/68193
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10
Activation of NF-κ B signalling pathway by inflammatory regulators and associated drug discovering
Autor: XiRong Guo, YuZhu Peng, QingSong Zhao, Xiaofeng Shen, ShanWu Feng, Shiqin Xu, Yusheng Liu, Fuzhou Wang, Xiaohong Li
Publikováno v: Internet Journal of Medical Update-EJOURNAL; Vol 5, No 2 (2010)
Intracellular signalling transduction plays a pivotal role in cell activation,and the regulation of gene transcription needs the involvement of series of nuclear factors. Nuclear transcription factor- kappa B, one of the key factors in mediating gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921784232a3770d729be78c72d9e73e4
https://www.ajol.info/index.php/ijmu/article/view/56162
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