Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Drug pipeline"'
Autor:
Filippo Gabrielli, Eleonora Crepaldi, Alessia Cavicchioli, Marco Rivi, Arianna Carmen Costanzo, Carmela Cursaro, Pietro Andreone
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1227 (2024)
Cholestasis is a clinical and laboratory syndrome indicating impaired bile production or excretion. One of the hallmark symptoms of cholestasis is pruritus. Itch can be severe and debilitating for patients, impacting their quality of life similarly t
Externí odkaz:
https://doaj.org/article/c89d1f6f15ba4c3589967ef1b1d34e7a
Publikováno v:
Applied Network Science, Vol 5, Iss 1, Pp 1-25 (2020)
Abstract Drug development is a time-consuming process from the start of research to obtaining approval, and the probability of success with a candidate compound is extremely low. We aim to understand the characteristics of the flow and localization o
Externí odkaz:
https://doaj.org/article/cd67f3d6f2a94764a5dbaf58c11c5aef
Akademický článek
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Akademický článek
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Autor:
Ana Isabel Olías-Molero, Concepción de la Fuente, Montserrat Cuquerella, Juan J. Torrado, José M. Alunda
Publikováno v:
Microorganisms, Vol 9, Iss 12, p 2500 (2021)
Leishmaniasis is a vector-borne parasitic disease caused by Leishmania species. The disease affects humans and animals, particularly dogs, provoking cutaneous, mucocutaneous, or visceral processes depending on the Leishmania sp. and the host immune r
Externí odkaz:
https://doaj.org/article/147b76a9b8324a3096e505caac663796
Autor:
Takafira Mduluza, Francisca Mutapi
Publikováno v:
Infectious Diseases of Poverty, Vol 6, Iss 1, Pp 1-6 (2017)
Abstract Despite increased international efforts to control schistosomiasis using preventive chemotherapy, several challenges still exist in reaching the target populations. Until recently, preschool-aged children had been excluded from the recommend
Externí odkaz:
https://doaj.org/article/89c7d150fbca49efa076964906e2b7e1
Autor:
Gill Langley, J. Mark Treherne
Publikováno v:
Drug Discovery Today
Spiralling research costs combined with urgent pressures from the Coronavirus 2019 (COVID-19) pandemic and the consequences of climate disruption are forcing changes in drug discovery. Increasing the predictive power of in vitro human assays and usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68f839758d7827be39b76b3d99a4dd9
https://doi.org/10.1016/j.drudis.2021.05.001
https://doi.org/10.1016/j.drudis.2021.05.001
Autor:
Leslie C. Norins
Publikováno v:
Journal of Alzheimer's Disease
Substantial evidence, composed of drug mechanisms of action, in vivo testing, and epidemiological data, exists to support clinical testing of FDA-approved drugs for repurposing to the treatment of Alzheimer’s disease (AD). Licensed compound investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62e282541afb30307cc3e411716a6e9
https://doi.org/10.3233/jad-210080
https://doi.org/10.3233/jad-210080
Autor:
Vinayak Singh, Kelly Chibale
Publikováno v:
Accounts of Chemical Research
Conspectus “Drug resistance is an unavoidable consequence of the use of drugs; however, the emergence of multi-drug resistance can be managed by accurate diagnosis and tailor-made regimens.” Antimicrobial resistance (AMR), is one of the most para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55acf333b80edc8923169f5313f67ba
http://europepmc.org/articles/PMC8154215
http://europepmc.org/articles/PMC8154215
Autor:
Laura DeFrancesco
Publikováno v:
Nature Biotechnology. 39:1326-1328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a48d57c584f33c3106e8b3c552b2372
https://doi.org/10.1038/s41587-021-01119-8
https://doi.org/10.1038/s41587-021-01119-8