Zobrazeno 1 - 10
of 1 283
pro vyhledávání: '"Drug dosing"'
Autor:
Mike Wells, Penelope Yende
Publikováno v:
Clinical and Experimental Emergency Medicine, Vol 11, Iss 2, Pp 145-160 (2024)
Objective The use of pediatric length-based weight estimation tapes with precalculated drug doses is advocated by major Advanced Life Support support organizations, but concerns have been raised on the accuracy of these systems. The objective of this
Externí odkaz:
https://doaj.org/article/ef3c940a027e41ca804f4deb170e82cf
Autor:
Mike Wells, Lara Nicole Goldstein, Terran Wells, Niloufar Ghazi, Abhijit Pandya, Borifoje Furht, Gabriella Engstrom, Muhammad Tanveer Jan, Richard Shih
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Background Weight estimation is required in adult patients when weight‐based medication must be administered during emergency care, as measuring weight is often not possible. Inaccurate estimations may lead to inaccurate drug dosing, which
Externí odkaz:
https://doaj.org/article/c32fc252625f4f4e808d8de14a28f33d
The many dimensions of combination therapy: How to combine antibiotics to limit resistance evolution
Publikováno v:
Evolutionary Applications, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract In combination therapy, bacteria are challenged with two or more antibiotics simultaneously. Ideally, separate mutations are required to adapt to each of them, which is a priori expected to hinder the evolution of full resistance. Yet, the s
Externí odkaz:
https://doaj.org/article/f230c9086a0e466d87373a7f0f500e10
Publikováno v:
Arhiv za farmaciju, Vol 74, Iss 3, Pp 483-508 (2024)
Obesity, a chronic disease, is increasingly prevalent worldwide, posing a significant public health challenge. It is often accompanied by comorbidities such as hypertension, cardiovascular disease, dyslipidemia, and diabetes, among others. Pharmacist
Externí odkaz:
https://doaj.org/article/a0447e39c01a412ca6ad6c1eddf25f96
Autor:
Weerachai Chaijamorn, Sathian Phunpon, Thanompong Sathienluckana, Taniya Charoensareerat, Sutthiporn Pattharachayakul, Dhakrit Rungkitwattanakul, Nattachai Srisawat
Publikováno v:
Journal of Intensive Care, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Background Lacosamide is one of the anticonvulsants used in critically ill patients. This study aimed to suggest appropriate lacosamide dosing regimens in critically ill patients receiving continuous renal replacement therapy (CRRT) via Mont
Externí odkaz:
https://doaj.org/article/369ed20d72a5474ca9e69ef49b63146a
Autor:
Xinyan Liu, Erin F. Barreto, Yue Dong, Chang Liu, Xiaolan Gao, Mohammad Samie Tootooni, Xuan Song, Kianoush B. Kashani
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Artificial intelligence (AI) tools are more effective if accepted by clinicians. We developed an AI-based clinical decision support system (CDSS) to facilitate vancomycin dosing. This qualitative study assesses clinicians' percept
Externí odkaz:
https://doaj.org/article/ed66a0633f1143ee91915d0803eb35dd
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 13, Iss 1, Pp 70-74 (2023)
The largest study on cyclophosphamide pharmacokinetics in dialysis patients comprises of 6 subjects. In the 2 decades since these data were obtained, dialyser membranes, treatment intensities, and treatment duration have changed considerably making n
Externí odkaz:
https://doaj.org/article/c51a4801992e4faa989747f51a4ed989
Autor:
Alexandra Burr, Patrick Erickson, Raphaela Bento, Kariman Shama, Charles Roth, Biju Parekkadan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 368-379 (2022)
The use of adeno-associated virus (AAV) as a gene delivery vehicle for secreted peptide therapeutics can enable a new approach to durably manage chronic protein insufficiencies in patients. Yet, dosing of AAVs have been largely empirical to date. In
Externí odkaz:
https://doaj.org/article/e3e98773f95d4a3a8ef0c69fa7244bbe
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 12, Iss 3, Pp 145-149 (2022)
In parallel with the decline of renal excretory function, drug dosing of many drugs becomes more challenging. Finding the right dose is even more difficult if kidney replacement therapy is instituted. This is further aggravated by the fact that even
Externí odkaz:
https://doaj.org/article/d489cb915323475abec20b3fe7b97445
Autor:
Francesca Gaeta, Valeria Conti, Angela Pepe, Pietro Vajro, Amelia Filippelli, Claudia Mandato
Publikováno v:
Italian Journal of Pediatrics, Vol 48, Iss 1, Pp 1-14 (2022)
Abstract Childhood obesity and its associated comorbidities are highly prevalent diseases that may add to any other possible health problem commonly affecting the pediatric age. Uncertainties may arise concerning drug dosing when children with obesit
Externí odkaz:
https://doaj.org/article/72579b2a3b7a47a8a3d199f6cd95c121