Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance

Autor: Munk, Patrick, Brinch, Christian, Møller, Frederik Duus, Petersen, Thomas N., Hendriksen, Rene S., Seyfarth, Anne Mette, Kjeldgaard, Jette S., Svendsen, Christina Aaby, van Bunnik, Bram, Berglund, Fanny, Bego, Artan, Power, Pablo, Rees, Catherine, Lambrinidis, Dionisia, Neilson, Elizabeth Heather Jakobsen, Gibb, Karen, Coventry, Kris, Collignon, Peter, Cassar, Susan, Allerberger, Franz, Begum, Anowara, Hossain, Zenat Zebin, Worrell, Carlon, Vandenberg, Olivier, Pieters, Ilse, Victorien, Dougnon Tamègnon, Gutierrez, Angela Daniela Salazar, Soria, Freddy, Grujić, Vesna Rudić, Mazalica, Nataša, Rahube, Teddie O., Tagliati, Carlos Alberto, Rodrigues, Dalia, Oliveira, Guilherme, de Souza, Larissa Camila Ribeiro, Ivanov, Ivan, Juste, Bonkoungou Isidore, Oumar, Traoré, Sopheak, Thet, Vuthy, Yith, Ngandijo, Antoinette, Nzouankeu, Ariane, Olivier, Ziem A. Abah Jacques, Yost, Christopher K., Kumar, Pratik, Brar, Satinder Kaur, Tabo, Djim-Adjim, Adell, Aiko D., Paredes-Osses, Esteban, Martinez, Maria Cristina, Cuadros-Orellana, Sara, Ke, Changwen, Zheng, Huanying, Baisheng, Li, Lau, Lok Ting, Chung, Teresa, Jiao, Xiaoyang, Yu, Yongjie, JiaYong, Zhao, Morales, Johan F. Bernal, Valencia, Maria Fernanda, Donado-Godoy, Pilar, Coulibaly, Kalpy Julien, Hrenovic, Jasna, Jergović, Matijana, Karpíšková, Renáta, Deogratias, Zozo Nyarukweba, Elsborg, Bodil, Hansen, Lisbeth Truelstrup, Jensen, Pernille Erland, Abouelnaga, Mohamed, Salem, Mohamed Fathy, Koolmeister, Marliin, Legesse, Mengistu, Eguale, Tadesse, Heikinheimo, Annamari, Le Guyader, Soizick, Schaeffer, Julien, Villacis, Jose Eduardo, Sanneh, Bakary, Malania, Lile, Nitsche, Andreas, Brinkmann, Annika, Schubert, Sara, Hesse, Sina, Berendonk, Thomas U., Saba, Courage Kosi Setsoafia, Mohammed, Jibril, Feglo, Patrick Kwame, Banu, Regina Ama, Kotzamanidis, Charalampos, Lytras, Efthymios, Lickes, Sergio A., Kocsis, Bela, Solymosi, Norbert, Thorsteinsdottir, Thorunn R., Hatha, Abdulla Mohamed, Ballal, Mamatha, Bangera, Sohan Rodney, Fani, Fereshteh, Alebouyeh, Masoud, Morris, Dearbhaile, O’Connor, Louise, Cormican, Martin, Moran-Gilad, Jacob, Battisti, Antonio, Diaconu, Elena Lavinia, Corno, Gianluca, Di Cesare, Andrea, Alba, Patricia, Hisatsune, Junzo, Yu, Liansheng, Kuroda, Makoto, Sugai, Motoyuki, Kayama, Shizuo, Shakenova, Zeinegul, Kiiyukia, Ciira, Ng’eno, Eric, Raka, Lul, Jamil, Kazi, Fakhraldeen, Saja Adel, Alaati, Tareq, Bērziņš, Aivars, Avsejenko, Jeļena, Kokina, Kristina, Streikisa, Madara, Bartkevics, Vadims, Matar, Ghassan M., Daoud, Ziad, Pereckienė, Asta, Butrimaite-Ambrozeviciene, Ceslova, Penny, Christian, Bastaraud, Alexandra, Rasolofoarison, Tiavina, Collard, Jean-Marc, Samison, Luc Hervé, Andrianarivelo, Mala Rakoto, Banda, Daniel Lawadi, Amin, Arshana, Rajandas, Heraa, Parimannan, Sivachandran, Spiteri, David, Haber, Malcolm Vella, Santchurn, Sunita J., Vujacic, Aleksandar, Djurovic, Dijana, Bouchrif, Brahim, Karraouan, Bouchra, Vubil, Delfino Carlos, Pal, Pushkar, Schmitt, Heike, van Passel, Mark, Jeunen, Gert-Jan, Gemmell, Neil, Chambers, Stephen T., Mendoza, Fania Perez, Huete-Pιrez, Jorge, Vilchez, Samuel, Ahmed, Akeem Olayiwola, Adisa, Ibrahim Raufu, Odetokun, Ismail Ayoade, Fashae, Kayode, Sørgaard, Anne-Marie, Wester, Astrid Louise, Ryrfors, Pia, Holmstad, Rune, Mohsin, Mashkoor, Hasan, Rumina, Shakoor, Sadia, Gustafson, Natalie Weiler, Schill, Claudia Huber, Rojas, Maria Luz Zamudio, Velasquez, Jorge Echevarria, Magtibay, Bonifacio B., Catangcatang, Kris, Sibulo, Ruby, Yauce, Felipe Campos, Wasyl, Dariusz, Manaia, Celia, Rocha, Jaqueline, Martins, Jose, Álvaro, Pedro, Di Yoong Wen, Doris, Shin, Hanseob, Hur, Hor-Gil, Yoon, Sukhwan, Bosevska, Golubinka, Kochubovski, Mihail, Cojocaru, Radu, Burduniuc, Olga, Hong, Pei-Ying, Perry, Meghan Rose, Gassama, Amy, Radosavljevic, Vladimir, Tay, Moon Y. F., Zuniga-Montanez, Rogelio, Wuertz, Stefan, Gavačová, Dagmar, Pastuchová, Katarína, Truska, Peter, Trkov, Marija, Keddy, Karen, Esterhuyse, Kerneels, Song, Min Joon, Quintela-Baluja, Marcos, Lopez, Mariano Gomez, Cerdà-Cuéllar, Marta, Perera, R.R.D.P., Bandara, N.K.B.K.R.G.W., Premasiri, H.I., Pathirage, Sujatha, Charlemagne, Kareem, Rutgersson, Carolin, Norrgren, Leif, Örn, Stefan, Boss, Renate, Van der Heijden, Tanja, Hong, Yu-Ping, Kumburu, Happiness Houka, Mdegela, Robinson Hammerthon, Hounmanou, Yaovi Mahuton Gildas, Chonsin, Kaknokrat, Suthienkul, Orasa, Thamlikitkul, Visanu, de Roda Husman, Ana Maria, Bidjada, Bawimodom, Njanpop-Lafourcade, Berthe-Marie, Nikiema-Pessinaba, Somtinda Christelle, Levent, Belkis, Kurekci, Cemil, Ejobi, Francis, Kalule, John Bosco, Thomsen, Jens, Obaidi, Ouidiane, Jassim, Laila Mohamed, Moore, Andrew, Leonard, Anne, Graham, David W., Bunce, Joshua T., Zhang, Lihong, Gaze, William H., Lefor, Brett, Capone, Drew, Sozzi, Emanuele, Brown, Joe, Meschke, John Scott, Sobsey, Mark D., Davis, Michael, Beck, Nicola Koren, Sukapanpatharam, Pardi, Truong, Phuong, Lilienthal, Ronald, Kang, Sanghoon, Wittum, Thomas E., Rigamonti, Natalia, Baklayan, Patricia, Van, Chinh Dang, Tran, Doan Minh Nguyen, Do Phuc, Nguyen, Kwenda, Geoffrey, Larsson, D. G. Joakim, Koopmans, Marion, Woolhouse, Mark, Aarestrup, Frank M.

Publikováno v: Nature Communications, 13(1):7251. Nature Publishing Group
Nature Communications
Nature Communications (2041-1723) (Springer Science and Business Media LLC), 2022-12, Vol. 13, N. 1, P. 7251 (16p.)
Munk, P, Brinch, C, Møller, F D, Petersen, T N, Hendriksen, R S, Seyfarth, A M, Kjeldgaard, J S, Svendsen, C A, van Bunnik, B, Berglund, F, Global, S S C, Larsson, D G J, Koopmans, M, Woolhouse, M & Aarestrup, F M 2022, ' Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance ', Nature Communications, vol. 13, no. 1, 7251 . https://doi.org/10.1038/s41467-022-34312-7
Munk, P, Brinch, C, Møller, F D, Petersen, T N, Hendriksen, R S, Seyfarth, A M, Kjeldgaard, J S, Svendsen, C A, van Bunnik, B, Berglund, F, Bego, A, Power, P, Rees, C, Lambrinidis, D, Neilson, E H J, Gibb, K, Coventry, K, Collignon, P, Cassar, S, Allerberger, F, Begum, A, Hossain, Z Z, Worrell, C, Vandenberg, O, Pieters, I, Victorien, D T, Gutierrez, A D S, Soria, F, Grujić, V R, Mazalica, N, Rahube, T O, Tagliati, C A, Rodrigues, D, Oliveira, G, de Souza, L C R, Ivanov, I, Juste, B I, Oumar, T, Sopheak, T, Vuthy, Y, Ngandijo, A, Nzouankeu, A, Olivier, Z A A J, Yost, C K, Hansen, L T, Jensen, P E, Parimannan, S, Hounmanou, Y M G, Thomsen, J, Aarestrup, F M & Global Sewage Surveillance Consortium 2022, ' Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance ', Nature Communications, vol. 13, 7251 . https://doi.org/10.1038/s41467-022-34312-7
Munk, P, Brinch, C, Møller, F D, Petersen, T N, Hendriksen, R S, Seyfarth, A M, Kjeldgaard, J, Svendsen, C A, van Bunnik, B A D, Berglund, F, Larsson, D G J, Koopmans, M P G & Woolhouse, M & Aarestrup, F M 2022, ' Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance ', Nature Communications, vol. 13, 7251 . https://doi.org/10.1038/s41467-022-34312-7

Antimicrobial resistance (AMR) is a major threat to global health. Understanding the emergence, evolution, and transmission of individual antibiotic resistance genes (ARGs) is essential to develop sustainable strategies combatting this threat. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303f29efecb5b8304deef73449e4f6cd
https://pure.eur.nl/en/publications/a8b1eb7a-a1f6-4d66-aec6-d86b000f9453

Direct assessment of possible mutations in the 23S rRNA gene encoding macrolide resistance in Chlamydia trachomatis

Autor: J. M. van Niekerk, I. H. M. van Loo, M. Lucchesi, S. A. Morré, C. J. P. A. Hoebe, N. H. T. M. Dukers-Muijrers, P. F. G. Wolffs

Publikováno v: PLOS ONE, 17(5):e0265229. Public Library of Science

Reports of potential treatment failure have raised particular concerns regarding the efficacy of the single dose azithromycin regimen in the treatment of urogenital and anorectal Chlamydia trachomatis (CT) infections. Several factors have been sugges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb59d416da39475442473c81b464391
https://cris.maastrichtuniversity.nl/en/publications/c753ad21-641b-493e-bbbe-92ca99a644ed

Mycoplasma genitalium prevalence and macrolide resistance-associated mutations and coinfection with Chlamydia trachomatis in Southern Jutland, Denmark

Autor: Rasmus Desdorf, Niles Moller Andersen, Ming Chen

Publikováno v: Desdorf, R, Andersen, N M & Chen, M 2021, ' Mycoplasma genitalium prevalence and macrolide resistance-associated mutations and coinfection with Chlamydia trachomatis in Southern Jutland, Denmark ', A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica (Online), vol. 129, no. 12, pp. 706-710 . https://doi.org/10.1111/apm.13174

This study aims to investigate prevalence of Mycoplasma genitalium and macrolide resistance-associated mutations and coinfection with other sexually transmitted bacteria in Southern Jutland, Denmark, where this information is very limited. Urinary sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1cfacba4826d2c39ac112724bef6d2d
https://findresearcher.sdu.dk:8443/ws/files/194106006/Open_Access_Version.pdf

Effects of antibiotic duration on the intestinal microbiota and resistome: The PIRATE RESISTANCE project, a cohort study nested within a randomized trial

Autor: Jacques Schrenzel, Benedikt Huttner, Elodie von Dach, Laurent Kaiser, Vladimir Lazarevic, Virginie Prendki, Angela Huttner, Stefano Leo

Publikováno v: EBioMedicine, Vol 71, Iss, Pp 103566-(2021)
EBioMedicine
EBioMedicine, Vol. 71 (2021) P. 103566

Background: Shortening antibiotic-treatment durations is a key recommendation of antibiotic-stewardship programmes, yet it is based on weak evidence. We investigated whether halving antibiotic courses would reduce antibiotic-resistance genes (ARG) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d968b1b330d06f371f7d572c1b0b7240
https://doi.org/10.1016/j.ebiom.2021.103566

Prediction of the intestinal resistome by a three-dimensional structure-based method

Autor: Willem van Schaik, Kevin Weiszer, Nicolas Maziers, Hervé M. Blottière, Luis Máiz, Nicolas Pons, Fernando Baquero, S. Dusko Ehrlich, Bruno Fantin, José L. Martínez, Amine Ghozlane, Julien Tap, Malbert R. C. Rogers, Pierre Leonard, Rob J. L. Willems, Anne-Sophie Alvarez, Florence Haimet, Etienne Ruppé, Sara Hernando-Amado, Victoire de Lastours, Alexandre G. de Brevern, Tiphaine Goulenok, Ingrid Wieder, Xinglin Zhang, Antoine Andremont, Trinidad Cuesta, Véronique Léjard, Jean-Michel Batto, Aline Letur, Nawal Amor, Joël Doré, Val F. Lanza, Teresa M. Coque, Florence Levenez, Irene Clares, Sean Kennedy

Publikováno v: Nature Microbiology
Nature Microbiology, 2019, 4 (1), pp.112-123. ⟨10.1038/s41564-018-0292-6⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nature Microbiology, Nature Publishing Group, 2019, 4 (1), pp.112-123. ⟨10.1038/s41564-018-0292-6⟩

The intestinal microbiota is considered to be a major reservoir of antibiotic resistance determinants (ARDs) that could potentially be transferred to bacterial pathogens via mobile genetic elements. Yet, this assumption is poorly supported by empiric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7013f5a41bcc5881d24199865534323
https://hal-pasteur.archives-ouvertes.fr/pasteur-02552015