Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Drug Discovery for Neglected Diseases"'
Autor:
E. L. Habib Dakir, Julio López-Abán, Antonio Muro, Rubén E. Varela-M, Edward Yepes, Faustino Mollinedo
Publikováno v:
PLoS ONE
Yepes, E, Varela-M, R E, Lopez-Aban, J, Dakir, E L H, Mollinedo, F & Muro, A 2014, ' In Vitro and In Vivo Anti-Schistosomal Activity of the Alkylphospholipid Analog Edelfosine ', PLoS ONE, vol. 9, no. 10, e109431 . https://doi.org/10.1371/journal.pone.0109431
Digital.CSIC. Repositorio Institucional del CSIC
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PLoS ONE, Vol 9, Iss 10, p e109431 (2014)
Yepes, E, Varela-M, R E, Lopez-Aban, J, Dakir, E L H, Mollinedo, F & Muro, A 2014, ' In Vitro and In Vivo Anti-Schistosomal Activity of the Alkylphospholipid Analog Edelfosine ', PLoS ONE, vol. 9, no. 10, e109431 . https://doi.org/10.1371/journal.pone.0109431
Digital.CSIC. Repositorio Institucional del CSIC
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PLoS ONE, Vol 9, Iss 10, p e109431 (2014)
This is an open-access article distributed under the terms of the Creative Commons Attribution License.
[Background]: Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. Five species of Schistosoma are known to
[Background]: Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. Five species of Schistosoma are known to
Autor:
Raul O Cosentino, Fernán Agüero
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96762 (2014)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
In Trypanosoma cruzi the isoprenoid and sterol biosynthesis pathways are validated targets for chemotherapeutic intervention. In this work we present a study of the genetic diversity observed in genes from these pathways. Using a number of bioinforma
Autor:
Rosiane Freire dos Santos, Luciana de Moraes Costa, Paulo R. R. Costa, P. M. L. Dutra, Silvia Amaral Gonçalves Da-Silva, Roberta Olmo Pinheiro, Alcides J. M. da Silva, Edézio Ferreira Cunha-Júnior, Eduardo Caio Torres-Santos
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109672 (2014)
PLoS ONE
PLoS ONE
Previous results demonstrate that the hybrid synthetic pterocarpanquinone LQB-118 presents antileishmanial activity against Leishmania amazonensis in a mouse model. The aim of the present study was to use a hamster model to investigate whether LQB-11
Autor:
Robert M. Greenberg, Lalit Kumar Sharma, Thomas R. Webb, Ravi S. Kasinathan, Charles E. Cunningham
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 8, Iss 10, p e3265 (2014)
PLoS Neglected Tropical Diseases, Vol 8, Iss 10, p e3265 (2014)
Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and