Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Drug Carriers/chemistry"'
Publikováno v:
Proceedings of the National Academy of Science of the United States of America. 120(27)
The design of stimuli-responsive systems in nanomedicine arises from the challenges associated with the unsolved needs of current molecular drug delivery. Here, we present a delivery system with high spatiotemporal control and tunable release profile
Autor:
Gholamreza Dehghan, Elham Kamalkazemi, Nader Sheibani, Fereydoon Abedi-Gaballu, Ali Mohammadi, Tala Farid Mohammad Hosseini, Behzad Mansoori, Behzad Baradaran
Publikováno v:
Kazemi, E K, Abedi-Gaballu, F, Mohammad Hosseini, T F, Mohammadi, A, Mansoori, B, Dehghan, G, Baradaran, B & Sheibani, N 2022, ' Glimpse into the Cellular Internalization and Intracellular Trafficking of Lipid-Based Nanoparticles in Cancer Cells ', Anti-Cancer Agents in Medicinal Chemistry, vol. 22, no. 10, pp. 1897-1912 . https://doi.org/10.2174/1871520621666210906101421
Lipid-based nanoparticles as drug delivery carriers have been mainly used for delivery of anti-cancer therapeutic agents. Lipid-based nanoparticles, due to their smaller particle size and similarity to cell membranes, are readily internalized into ca
Autor:
Thomas L. Moore, Alexander B. Cook, Elena Bellotti, Roberto Palomba, Purnima Manghnani, Raffaele Spanò, Sayanti Brahmachari, Martina Di Francesco, Anna Lisa Palange, Daniele Di Mascolo, Paolo Decuzzi
Publikováno v:
Drug Delivery and Translational Research, 12(8), 2019-2037. Springer
The storied history of controlled the release systems has evolved over time; from degradable drug-loaded sutures to monolithic zero-ordered release devices and nano-sized drug delivery formulations. Scientists have tuned the physico-chemical properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1122adc9e90d8e637f3bb4ca03c2e85b
https://hdl.handle.net/11589/247700
https://hdl.handle.net/11589/247700
Autor:
Robert Gurny, Yogeshvar N. Kalia, Michael Möller, Margaux Mignot, Maria Lapteva, Karine Mondon
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 142 (2019) pp. 553-562
mPEG-hexPLA micelles have shown their ability to improve delivery and cutaneous bioavailability of a wide range of poorly water soluble and lipophilic molecules. Although poorly water soluble, imiquimod (IMQ) is only moderately lipophilic and it was
Autor:
Soudeh F. Tehrani, Patrice Hildgen, Vahid Adibnia, Xavier Banquy, Steven Sanche, Jean-Michel Rabanel, Charles Ramassamy
Publikováno v:
Nanoscale
Nanoscale, Royal Society of Chemistry, 2019, 11 (2), pp.383-406. ⟨10.1039/c8nr04916e⟩
Nanoscale, Royal Society of Chemistry, 2019, 11 (2), pp.383-406. ⟨10.1039/c8nr04916e⟩
International audience; Drug nanocarriers' surface chemistry is often presumed to be uniform. For instance, the polymer surface coverage and distribution of ligands on nanoparticles are described with averaged values obtained from quantification tech
Autor:
Andrea Caporali, Craig R. Christie, Catriona H. Edwards, Antonella Celluzzi, Andrea Masotti, Ewan M. Campbell
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Edwards, C H, Christie, C R, Masotti, A, Celluzzi, A, Caporali, A & Campbell, E M 2020, ' Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum ', Scientific Reports, vol. 10, no. 1, pp. 12422 . https://doi.org/10.1038/s41598-020-69068-x
Scientific Reports
Edwards, C H, Christie, C R, Masotti, A, Celluzzi, A, Caporali, A & Campbell, E M 2020, ' Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum ', Scientific Reports, vol. 10, no. 1, pp. 12422 . https://doi.org/10.1038/s41598-020-69068-x
Scientific Reports
In this study, the use of dendrimer-coated carbon nanotubes (CNTs) as a delivery vehicle for dsRNA was assessed in Tribolium castaneum. Exposure to low dosages of polyamidoamine dendrimer carbon nanotubes (PAMAM-CNTs) did not affect T. castaneum larv
Autor:
Giulio Maria Conte, Pietro Campiglia, Tiziana Esposito, Eduardo Sommella, Rita Patrizia Aquino, Giulia Auriemma, Francesca Sansone
Publikováno v:
Molecules, Vol 25, Iss 2086, p 2086 (2020)
Molecules
Volume 25
Issue 9
Molecules
Volume 25
Issue 9
Spirulina platensis contains several compounds showing nutritional and therapeutic benefits. Recently, a series of peptides able to reduce the blood pressure level and to enhance the endothelial vasorelaxation was isolated from the hydrolyzed highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ed5574ed95c7b220fe4c1da1b85d57
https://hdl.handle.net/20.500.14017/ee7dbf71-952a-4e0c-ae2f-367bb997e540
https://hdl.handle.net/20.500.14017/ee7dbf71-952a-4e0c-ae2f-367bb997e540
Autor:
Elisabeth Garanger, Jan C. M. van Hest, Evangelos Georgilis, Jan Pille, Sébastien Lecommandoux, Esra Aydinlioglu, Mona Abdelghani
Publikováno v:
International Journal of Pharmaceutics
International Journal of Pharmaceutics, 2020, 586, pp.119537. ⟨10.1016/j.ijpharm.2020.119537⟩
International Journal of Pharmaceutics, 586:119537. Elsevier
INTERNATIONAL JOURNAL OF PHARMACEUTICS
International Journal of Pharmaceutics, Elsevier, 2020, 586, pp.119537. ⟨10.1016/j.ijpharm.2020.119537⟩
International Journal of Pharmaceutics, 2020, 586, pp.119537. ⟨10.1016/j.ijpharm.2020.119537⟩
International Journal of Pharmaceutics, 586:119537. Elsevier
INTERNATIONAL JOURNAL OF PHARMACEUTICS
International Journal of Pharmaceutics, Elsevier, 2020, 586, pp.119537. ⟨10.1016/j.ijpharm.2020.119537⟩
International audience; Medicine formulations at the nanoscale, referred to as nanomedicines, have managed to overcome key challenges encountered during the development of new medical treatments and entered clinical practice, but considerable improve
Autor:
Aleksandra Wincenciuk, Dorota Gryko, Joanna Trylska, Ksenia Maximova, Aleksandra J. Wierzba, Monika Wojciechowska, Marcin Równicki, Ebba Nexo
Publikováno v:
Wierzba, A J, Maximova, K, Wincenciuk, A, Równicki, M, Wojciechowska, M, Nexø, E, Trylska, J & Gryko, D 2018, ' Does a Conjugation Site Affect Transport of Vitamin B12-Peptide Nucleic Acid Conjugates into Bacterial Cells? ', Chemistry: A European Journal, vol. 24, no. 70, pp. 18772-18778 . https://doi.org/10.1002/chem.201804304
Gram-negative bacteria develop specific systems for the uptake of scarce nutrients, including vitamin B12 . These uptake pathways may be utilized for the delivery of biologically relevant molecules into cells. Indeed, it was recently reported that vi
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11(7):2127-2135
Low back pain is a major cause of disability and is heavily associated with intervertebral disc degeneration. Osteogenic protein 1 (OP-1) is a growth factor that has shown potential to regenerate the intervertebral disc in human cells and animal mode