The Neurobeachin-like 2 protein (NBEAL2) controls the homeostatic level of the ribosomal protein RPS6 in mast cells.

Autor: Wegner P; Institut für Immunologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany., Drube J; Institut für Molekulare Zellbiologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany., Ziegler L; Institut für Immunologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany., Strotmann B; Institut für Immunologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany., Marquardt R; Institut für Immunologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany., Küchler C; Institut für Immunologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany., Groth M; CF Next-Generation Sequencing, Fritz Lipmann Institute, Jena, Germany., Nieswandt B; Institute of Experimental Biomedicine, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany., Andreas N; Institut für Immunologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany., Drube S; Institut für Immunologie, Friedrich-Schiller-Universität Jena, Universitätsklinikum Jena, Jena, Germany.

Publikováno v: Immunology [Immunology] 2024 May; Vol. 172 (1), pp. 61-76. Date of Electronic Publication: 2024 Jan 25.

Beyond muscles: Investigating immunoregulatory myokines in acute resistance exercise - A systematic review and meta-analysis.

Autor: Ringleb M; Department of Movement Science, University of Münster, Münster, Germany.; Department of Sports Medicine and Health Promotion, Friedrich-Schiller-University Jena, Jena, Germany.; Department for Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.; Center for Interdisciplinary Prevention of Diseases related to Professional Activities, Friedrich-Schiller-University Jena, Jena, Germany., Javelle F; Department for Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany., Haunhorst S; Department of Sports Medicine and Health Promotion, Friedrich-Schiller-University Jena, Jena, Germany.; Center for Interdisciplinary Prevention of Diseases related to Professional Activities, Friedrich-Schiller-University Jena, Jena, Germany., Bloch W; Department for Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany., Fennen L; Department of Movement Science, University of Münster, Münster, Germany., Baumgart S; Institute for Immunology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany., Drube S; Institute for Immunology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany., Reuken PA; Clinic for Internal Medicine IV (Gastroenterology, Hepatology and Infectious Diseases), Jena University Hospital, Jena, Germany., Pletz MW; Institute for Immunology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.; Institute for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany., Wagner H; Department of Movement Science, University of Münster, Münster, Germany., Gabriel HHW; Department of Sports Medicine and Health Promotion, Friedrich-Schiller-University Jena, Jena, Germany., Puta C; Department of Sports Medicine and Health Promotion, Friedrich-Schiller-University Jena, Jena, Germany.; Center for Interdisciplinary Prevention of Diseases related to Professional Activities, Friedrich-Schiller-University Jena, Jena, Germany.; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Apr 15; Vol. 38 (7), pp. e23596.

The IL-33-induced p38-/JNK1/2-TNFα axis is antagonized by activation of β-adrenergic-receptors in dendritic cells.

Autor: Helbig C; Institute of Immunology, Jena University Hospital, 07743, Jena, Germany., Weber F; Institute of Immunology, Jena University Hospital, 07743, Jena, Germany., Andreas N; Institute of Immunology, Jena University Hospital, 07743, Jena, Germany., Herdegen T; Institute for Experimental and Clinical Pharmacology, Medical School Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Gaestel M; Institute for Cell Biochemistry, Medical School Hannover, Hannover, 30625, Germany., Kamradt T; Institute of Immunology, Jena University Hospital, 07743, Jena, Germany., Drube S; Institute of Immunology, Jena University Hospital, 07743, Jena, Germany. Sebastian.Drube@med.uni-jena.de.

Publikováno v: Scientific reports [Sci Rep] 2020 May 18; Vol. 10 (1), pp. 8152. Date of Electronic Publication: 2020 May 18.

IL-33-activated murine mast cells control the dichotomy between RORγt ⁺ and Helios ⁺ T regs via the MK2/3-mediated IL-6 production in vitro.

Autor: Andreas N; Institut für Immunologie, Universitätsklinikum Jena, Jena, Germany., Weber F; Institut für Immunologie, Universitätsklinikum Jena, Jena, Germany., Meininger I; Institut für Immunologie, Universitätsklinikum Jena, Jena, Germany., Templin N; Institut für Immunologie, Universitätsklinikum Jena, Jena, Germany., Gaestel M; Institut für Zellbiochemie, Medizinische Hochschule Hannover, Hannover, Germany., Kamradt T; Institut für Immunologie, Universitätsklinikum Jena, Jena, Germany., Drube S; Institut für Immunologie, Universitätsklinikum Jena, Jena, Germany.

Publikováno v: European journal of immunology [Eur J Immunol] 2019 Dec; Vol. 49 (12), pp. 2159-2171. Date of Electronic Publication: 2019 Jul 30.

Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells.

Autor: Beyer M; Department of Toxicology, University Medical Center, 55131 Mainz, Germany., Henninger SJ; Department of Toxicology, University Medical Center, 55131 Mainz, Germany., Haehnel PS; Department of Hematology, Medical Oncology, and Pneumology, University Medical Center, 55131 Mainz, Germany; University Cancer Center, University Medical Center, Mainz, Germany; German Consortia for Translational Cancer Research, 55131 Mainz, Germany., Mustafa AM; Department of Toxicology, University Medical Center, 55131 Mainz, Germany; Department of Zoology, Faculty of Science, Aswan University, Aswan, Egypt., Gurdal E; Institute for Pharmacy, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Strasse 3, 06120 Halle (Saale), Germany; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Atasehir, Istanbul 34755, Turkey., Schubert B; Department of Toxicology, University Medical Center, 55131 Mainz, Germany., Christmann M; Department of Toxicology, University Medical Center, 55131 Mainz, Germany., Sellmer A; Institute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry I, University of Regensburg, 93053 Regensburg, Germany., Mahboobi S; Institute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry I, University of Regensburg, 93053 Regensburg, Germany., Drube S; Institute of Immunology, Jena University Hospital, 07743 Jena, Germany., Sippl W; Institute for Pharmacy, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Strasse 3, 06120 Halle (Saale), Germany., Kindler T; Department of Hematology, Medical Oncology, and Pneumology, University Medical Center, 55131 Mainz, Germany; University Cancer Center, University Medical Center, Mainz, Germany; German Consortia for Translational Cancer Research, 55131 Mainz, Germany., Krämer OH; Department of Toxicology, University Medical Center, 55131 Mainz, Germany. Electronic address: okraemer@uni-mainz.de.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2022 Mar 17; Vol. 29 (3), pp. 398-411.e4. Date of Electronic Publication: 2021 Nov 10.