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pro vyhledávání: '"Dru McIver-Jenkins"'
Liver-specific ceramide reduction alleviates steatosis and insulin resistance in alcohol-fed mice[S]
Autor:
Jason Correnti, Chelsea Lin, Jascha Brettschneider, Amy Kuriakose, Sookyoung Jeon, Eleonora Scorletti, Amanke Oranu, Dru McIver-Jenkins, Isabelle Kaneza, Delfin Buyco, Yedidya Saiman, Emma E. Furth, Josepmaria Argemi, Ramon Bataller, William L. Holland, Rotonya M. Carr
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 983-994 (2020)
Alcohol's impairment of both hepatic lipid metabolism and insulin resistance (IR) are key drivers of alcoholic steatosis, the initial stage of alcoholic liver disease (ALD). Pharmacologic reduction of lipotoxic ceramide prevents alcoholic steatosis a
Externí odkaz:
https://doaj.org/article/a511773def56488ea730bea59345852d
Autor:
Rotonya M. Carr, Chelsea Lin, Eleonora Scorletti, Emma E. Furth, Ramon Bataller, William L. Holland, Sookyoung Jeon, Jason Correnti, Amanke Oranu, Isabelle Kaneza, Josepmaria Argemi, Jascha Brettschneider, Delfin Gerard Buyco, Yedidya Saiman, Amy Kuriakose, Dru McIver-Jenkins
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 61, Iss 7, Pp 983-994 (2020)
Journal of Lipid Research, Vol 61, Iss 7, Pp 983-994 (2020)
Alcohol's impairment of both hepatic lipid metabolism and insulin resistance (IR) are key drivers of alcoholic steatosis, the initial stage of alcoholic liver disease (ALD). Pharmacologic reduction of lipotoxic ceramide prevents alcoholic steatosis a
Autor:
Dru McIver-Jenkins, Chelsea Lin, Bianca Williams, Abigail Haba, Rotonya M. Carr, Eleonora Scorletti, Isabelle Kaneza, Sookyoung Jeon, Jason Correnti, Amy Kuriakose, Jascha Brettschneider, Amanke Oranu
Publikováno v:
J Vis Exp
Lipid droplets (LDs) are bioactive organelles found within the cytosol of the most eukaryotic and some prokaryotic cells. LDs are composed of neutral lipids encased by a monolayer of phospholipids and proteins. Hepatic LD lipids, such as ceramides, a