Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dru Imrie"'
Autor:
Ana M. Vacaru, Antonio Fabio Di Narzo, Deanna L. Howarth, Orkhontuya Tsedensodnom, Dru Imrie, Ayca Cinaroglu, Salma Amin, Ke Hao, Kirsten C. Sadler
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 823-835 (2014)
The unfolded protein response (UPR) is a complex network of sensors and target genes that ensure efficient folding of secretory proteins in the endoplasmic reticulum (ER). UPR activation is mediated by three main sensors, which regulate the expressio
Externí odkaz:
https://doaj.org/article/f8f95406937b4c7ebfa17a14505e6e43
Autor:
Charles DeRossi, Daniela Stanga, Dhara Kadakia, Mark A. Lehrman, Ruhina Rafiq, Ningguo Gao, Shikha Nayar, Ana M. Vacaru, Dru Imrie, Hudson H. Freeze, Michael Sacher, Kirsten C. Sadler, Anastasia Baryshnikova, Ayca Cinaroglu, Miroslav P. Milev, Jaime Chu
Publikováno v:
Molecular Biology of the Cell
The trappc11 mutation in zebrafish causes a stressed UPR, leading to fatty liver disease. This phenotype is not due to a trafficking defect but instead results from N-glycosylation defects. Hypoglycosylation and lipid accumulation are also found in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a0fcb100c17ddc0ad70d2ddfdbd3fe
https://doi.org/10.1091/mbc.e15-08-0557
https://doi.org/10.1091/mbc.e15-08-0557
Autor:
Dru Imrie, Salma Amin, Ke Hao, Deanna L. Howarth, Antonio Fabio Di Narzo, Kirsten C. Sadler, Ana M. Vacaru, Ayca Cinaroglu, Orkhontuya Tsedensodnom
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 823-835 (2014)
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 823-835 (2014)
The unfolded protein response (UPR) is a complex network of sensors and target genes that ensure efficient folding of secretory proteins in the endoplasmic reticulum (ER). UPR activation is mediated by three main sensors, which regulate the expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd408484214a470f07be48ced178bc7
https://doi.org/10.1242/dmm.014472
https://doi.org/10.1242/dmm.014472
Publikováno v:
Hepatology. 54:495-508
Many etiologies of fatty liver disease (FLD) are associated with the hyperactivation of one of the three pathways composing the unfolded protein response (UPR), which is a harbinger of endoplasmic reticulum (ER) stress. The UPR is mediated by pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbe71cb5d3fdae60fd45792b918ab7e
https://doi.org/10.1002/hep.24396
https://doi.org/10.1002/hep.24396
Autor:
Dru Imrie, Kirsten C. Sadler
Publikováno v:
Developmental Dynamics. 239:3013-3023
Adipocytes are heterogeneous. Whether their differences are attributed to anatomical location or to different developmental origins is unknown. We investigated whether development of different white adipose tissue (WAT) depots in zebrafish occurs sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e92b7b0e38d797152bd109de9d97f7
https://doi.org/10.1002/dvdy.22443
https://doi.org/10.1002/dvdy.22443