Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals

Autor: Cohen, Alexander A., Keeffe, Jennifer R., Schiepers, Ariën, Dross, Sandra E., Greaney, Allison J., Rorick, Annie V., Gao, Han, Gnanapragasam, Priyanthi N.P., Fan, Chengcheng, West, Anthony P., Jr., Ramsingh, Arlene I., Erasmus, Jesse H., Pata, Janice D., Muramatsu, Hiromi, Pardi, Norbert, Lin, Paulo J.C., Baxter, Scott, Cruz, Rita, Quintanar-Audelo, Martina, Robb, Ellis, Serrano-Amatriain, Cristina, Magneschi, Leonardo, Fotheringham, Ian G., Fuller, Deborah H., Victora, Gabriel D., Bjorkman, Pamela J.

Publikováno v: In Cell 3 October 2024 187(20):5554-5571

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Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals.

Autor: Cohen AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally., Keeffe JR; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally., Schiepers A; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, 10065, USA., Dross SE; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.; National Primate Research Center, Seattle, WA 98121, USA., Greaney AJ; Medical Scientist Training Program, University of Washington, Seattle, WA 98195, USA., Rorick AV; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Gao H; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Gnanapragasam PNP; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Fan C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., West AP Jr; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Ramsingh AI; Creative BioSolutions, LLC, Miami, FL, 33131, USA., Erasmus JH; HDT Bio, Seattle, WA, 98109, USA., Pata JD; Wadsworth Center, New York State Department of Health and Department of Biomedical Sciences, University at Albany, Albany, NY, 12201, USA., Muramatsu H; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Pardi N; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lin PJC; Acuitas Therapeutics, Vancouver, BC V6T 1Z3, Canada., Baxter S; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Cruz R; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Quintanar-Audelo M; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.; Present address: Centre for Inflammation Research and Institute of Regeneration and Repair, The University of Edinburgh, Edinburgh, EH16 4UU, UK., Robb E; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Serrano-Amatriain C; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Magneschi L; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Fotheringham IG; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Fuller DH; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.; National Primate Research Center, Seattle, WA 98121, USA., Victora GD; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, 10065, USA., Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; Lead contact.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 22. Date of Electronic Publication: 2024 May 22.