Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Drorit Neumann"'
Autor:
Martina Rauner, Marta Murray, Sylvia Thiele, Deepika Watts, Drorit Neumann, Yankel Gabet, Lorenz C. Hofbauer, Ben Wielockx
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-8 (2021)
Abstract High erythropoietin (Epo) levels are detrimental to bone health in adult organisms. Adult mice receiving high doses of Epo lose bone mass due to suppressed bone formation and increased bone resorption. In humans, high serum Epo levels are li
Externí odkaz:
https://doaj.org/article/4622d615f5c64d3bb2fbacb231fd7459
Publikováno v:
Cells, Vol 12, Iss 13, p 1704 (2023)
Erythrocyte biogenesis needs to be tightly regulated to secure oxygen transport and control plasma viscosity. The cytokine erythropoietin (Epo) governs erythropoiesis by promoting cell proliferation, differentiation, and survival of erythroid precurs
Externí odkaz:
https://doaj.org/article/f025c406ff0c42fd830e8496d0267376
Autor:
Mostafa A. Aboouf, Franco Guscetti, Nadine von Büren, Julia Armbruster, Hyrije Ademi, Maja Ruetten, Florinda Meléndez-Rodríguez, Thomas Rülicke, Alexander Seymer, Robert A. Jacobs, Edith M. Schneider Gasser, Julian Aragones, Drorit Neumann, Max Gassmann, Markus Thiersch
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Erythropoietin receptor (EPOR) is widely expressed in healthy and malignant tissues. In certain malignancies, EPOR stimulates tumor growth. In healthy tissues, EPOR controls processes other than erythropoiesis, including mitochondrial metabolism. We
Externí odkaz:
https://doaj.org/article/310af4056b6044878b44d59abc419570
Autor:
Jennifer Ana Iden, Bitya Raphael-Mizrahi, Aaron Naim, Albert Kolomansky, Tamar Liron, Drorit Neumann, Marilena Vered, Yankel Gabet
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7773 (2023)
Five million non-melanoma skin cancers occur globally each year, and it is one of the most common malignant cancers. The dysregulation of the endocannabinoid system, particularly cannabinoid receptor 2 (CB2), is implicated in skin cancer development,
Externí odkaz:
https://doaj.org/article/12cc226157d942daa664e3607967f89c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/7178733b4a9949f0967305b920e2434e
Autor:
Zamzam Awida, Sahar Hiram-Bab, Almog Bachar, Hussam Saed, Dan Zyc, Anton Gorodov, Nathalie Ben-Califa, Sewar Omari, Jana Omar, Liana Younis, Jennifer Ana Iden, Liad Graniewitz Visacovsky, Ida Gluzman, Tamar Liron, Bitya Raphael-Mizrahi, Albert Kolomansky, Martina Rauner, Ben Wielockx, Yankel Gabet, Drorit Neumann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 12051 (2022)
Erythropoietin (EPO) is a pleiotropic cytokine that classically drives erythropoiesis but can also induce bone loss by decreasing bone formation and increasing resorption. Deletion of the EPO receptor (EPOR) on osteoblasts or B cells partially mitiga
Externí odkaz:
https://doaj.org/article/fadd650e158c4b2ab96699f84a359a83
Autor:
Edo Cohen-Karlik, Zamzam Awida, Ayelet Bergman, Shahar Eshed, Omer Nestor, Michelle Kadashev, Sapir Ben Yosef, Hussam Saed, Yishay Mansour, Amir Globerson, Drorit Neumann, Yankel Gabet
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In vitro osteoclastogenesis is a central assay in bone biology to study the effect of genetic and pharmacologic cues on the differentiation of bone resorbing osteoclasts. To date, identification of TRAP+ multinucleated cells and measurements of osteo
Externí odkaz:
https://doaj.org/article/a89ecc3980804171a4ca5624d901df48
Autor:
Zamzam Awida, Albert Kolomansky, Sahar Hiram-Bab, Nathalie Ben-Califa, Hussam Saad, Tamar Liron, Maria Ibrahim, Michael Brines, Yankel Gabet, Drorit Neumann
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100459- (2020)
Externí odkaz:
https://doaj.org/article/e7ea1871f99f405f99cc80ebbf30e0af
Autor:
Albert Kolomansky, Irit Kaye, Nathalie Ben-Califa, Anton Gorodov, Zamzam Awida, Ofer Sadovnic, Maria Ibrahim, Tamar Liron, Sahar Hiram-Bab, Howard S. Oster, Nadav Sarid, Chava Perry, Yankel Gabet, Moshe Mittelman, Drorit Neumann
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immunotherapy with anti-CD20-specific antibodies (rituximab), has become the standard of care for B cell lymphoproliferative disorders and many autoimmune diseases. In rheumatological patients the effect of rituximab on bone mass yielded conflicting
Externí odkaz:
https://doaj.org/article/8fe13af2d8c84491be39e81d8606f215
Autor:
Zamzam Awida, Almog Bachar, Hussam Saed, Anton Gorodov, Nathalie Ben-Califa, Maria Ibrahim, Albert Kolomansky, Jennifer Ana Iden, Liad Graniewitz Visacovsky, Tamar Liron, Sahar Hiram-Bab, Michael Brines, Yankel Gabet, Drorit Neumann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 55 (2021)
The two erythropoietin (EPO) receptor forms mediate different cellular responses to erythropoietin. While hematopoiesis is mediated via the homodimeric EPO receptor (EPOR), tissue protection is conferred via a heteromer composed of EPOR and CD131. In
Externí odkaz:
https://doaj.org/article/c3792960f2764f709744bc7d33e8422f