Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Dror Berel"'
Autor:
Lincoln A. Edwards, Aiguo Li, Dror Berel, Mecca Madany, Nam-Ho Kim, Minzhi Liu, Mitch Hymowitz, Benjamin Uy, Rachel Jung, Minlin Xu, Keith L. Black, Altan Rentsendorj, Xuemo Fan, Wei Zhang, John S. Yu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The identification of a stem cell regulatory gene which is aberrantly expressed in glioma and associated with patient survival would increase the understanding of the role of glioma cancer stem cells (GCSCs) in the virulence of gliomas. Inte
Externí odkaz:
https://doaj.org/article/20170381f56644fd9638ce225777a1a9
Autor:
Lincoln A. Edwards, Sungjin Kim, Mecca Madany, Miriam Nuno, Tom Thomas, Aiguo Li, Dror Berel, Bong-Sup Lee, Minzhi Liu, Keith L. Black, Xuemo Fan, Wei Zhang, John S. Yu
Publikováno v:
Frontiers in Neurology, Vol 9 (2019)
Objective: To address the unmet medical need to better prognosticate patients with diffuse gliomas and to predict responses to chemotherapy regimens.Methods: ZEB1 alterations were retrospectively identified from a cohort of 1,160 diffuse glioma patie
Externí odkaz:
https://doaj.org/article/14c9caa99ffc421bbd78903614a2ce9c
Autor:
Patricia Castro, Chad J. Creighton, Mustafa Ozen, Dror Berel, Martha P. Mims, Michael Ittmann
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 3, Pp 305-312 (2009)
African American (AA) men have a higher incidence and significantly higher mortality rates from prostate cancer than white men, but the biological basis for these differences are poorly understood. Few studies have been carried out to determine wheth
Externí odkaz:
https://doaj.org/article/404e312f61354249815a05c540ea6dfe
Autor:
Peizhen Hu, Leland W K Chung, Dror Berel, Henry F Frierson, Hua Yang, Chunyan Liu, Ruoxiang Wang, Qinlong Li, Andre Rogatko, Haiyen E Zhau
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73081 (2013)
We reported (PLoS One 6 (12):e28670, 2011) that the activation of c-Met signaling in RANKL-overexpressing bone metastatic LNCaP cell and xenograft models increased expression of RANK, RANKL, c-Met, and phosphorylated c-Met, and mediated downstream si
Externí odkaz:
https://doaj.org/article/78db664fa4b14490a60f4834bcb27a71
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54918 (2013)
Rapamycin analogs, temsirolimus and everolimus, are approved for the treatment of advance renal cell carcinoma (RCC). Currently approved agents inhibit mechanistic target of rapamycin (mTOR) complex 1 (mTORC1). However, the mTOR kinase exists in two
Externí odkaz:
https://doaj.org/article/0be335298182489f86107f3164770aba
Autor:
Sajni Josson, Yasuhiro Matsuoka, Murali Gururajan, Takeo Nomura, Wen-Chin Huang, Xiaojian Yang, Jin-Tai Lin, Roger Bridgman, Chia-Yi Chu, Peter A Johnstone, Majd Zayzafoon, Peizhen Hu, Haiyen Zhau, Dror Berel, Andre Rogatko, Leland W K Chung
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68366 (2013)
BACKGROUND:Bone metastasis is the most lethal form of several cancers. The β2-microglobulin (β2-M)/hemochromatosis (HFE) complex plays an important role in cancer development and bone metastasis. We demonstrated previously that overexpression of β
Externí odkaz:
https://doaj.org/article/f3d9efbbe5ae41cb91e2f3c95da75be1
Autor:
Don L Gibbons, Wei Lin, Chad J Creighton, Shuling Zheng, Dror Berel, Yanan Yang, Maria Gabriela Raso, Diane D Liu, Ignacio I Wistuba, Guillermina Lozano, Jonathan M Kurie
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5401 (2009)
Non-small cell lung cancer (NSCLC) is the foremost cause of cancer-related death in Western countries, which is due partly to the propensity of NSCLC cells to metastasize. The biologic basis for NSCLC metastasis is not well understood.Here we address
Externí odkaz:
https://doaj.org/article/b37ffd2a672949a59027720c2b7d2992
Autor:
George K. Hanna, Mecca Madany, Angelique Sao-Mai Sy Tay, Lincoln A. Edwards, Sungjin Kim, Justin S. Michael, Miriam Nuno, Tom Thomas, Aiguo Li, Dror Berel, Keith L. Black, Xuemo Fan, Wei Zhang, Jeremy D. Rudnick, Rongfu Wang, John S. Yu
Publikováno v:
Journal of Neurosurgery. :1-12
OBJECTIVE Glioblastoma has been known to be resistant to chemotherapy and radiation, whereas the underlying mechanisms of resistance have not been fully elucidated. The authors studied the role of the transcription factor ZEB1 (zinc finger E-box-bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a467b98acf05d6e05024a305ce7bb0
https://doi.org/10.3171/2022.7.jns22259
https://doi.org/10.3171/2022.7.jns22259
Autor:
Leland W.K. Chung, Dhruv Sareen, Ladan Fazli, Edwin M. Posadas, Dror Berel, Andre Rogatko, Quanlin Li, Srinivas Nandana, Jake Lichterman, Yi-Tsung Lu, Chia-Lun Lu, Kaiqin Lao, Chunyan Liu, Haiyen E. Zhau, Gina Chia-Yi Chu, Chen Shao, Peizhen Hu, Murali Gururajan, Sajni Josson
Effect of miR-409 overexpression in LNCaP cells. A, miR-409-5p and miR-409-3p levels in LNCaP control cells (LNCaP-C) and LNCaP miR-409 expressing cells (LNCaP-409) measured by qRT-PCR. B, Protein expression of RSU1 in LNCaP-C and LNCaP-409 PCa cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2621be83a70d3fc9ef2055c8108f952e
https://doi.org/10.1158/1078-0432.22454972
https://doi.org/10.1158/1078-0432.22454972
Autor:
Leland W.K. Chung, Dhruv Sareen, Ladan Fazli, Edwin M. Posadas, Dror Berel, Andre Rogatko, Quanlin Li, Srinivas Nandana, Jake Lichterman, Yi-Tsung Lu, Chia-Lun Lu, Kaiqin Lao, Chunyan Liu, Haiyen E. Zhau, Gina Chia-Yi Chu, Chen Shao, Peizhen Hu, Murali Gururajan, Sajni Josson
Gleason scores of the cancer from which the TMA cores were obtained and the miR-409 intensity counts by ISH-QD. None of the TMA cores had any treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0968b41ebf33aee8cc8dc2fb0a5f9639
https://doi.org/10.1158/1078-0432.22454960
https://doi.org/10.1158/1078-0432.22454960