Tumour infiltrating lymphocytes and survival after adjuvant chemotherapy in patients with gastric cancer: post-hoc analysis of the CLASSIC trial

Autor: Drolaiz H. W. Liu, Young-Woo Kim, Nina Sefcovicova, Jon P. Laye, Lindsay C. Hewitt, Andrew F. Irvine, Vincent Vromen, Yannick Janssen, Naser Davarzani, Gregorio E. Fazzi, Shahab Jolani, Veerle Melotte, Derek R. Magee, Myeong-Cherl Kook, Hyunki Kim, Rupert Langer, Jae-Ho Cheong, Heike I. Grabsch

Publikováno v: British Journal of Cancer, 128(12), 2318-2325. Nature Publishing Group

Background: Only a subset of gastric cancer (GC) patients with stage II–III benefits from chemotherapy after surgery. Tumour infiltrating lymphocytes per area (TIL density) has been suggested as a potential predictive biomarker of chemotherapy bene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d6ab45673e7601c5aa45e30593e3fe
https://doi.org/10.1038/s41416-023-02257-3

Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer

Autor: Ulf P. Neumann, Sven Arke Lang, Lara R. Heij, Jan Bednarsch, Georg Wiltberger, Jack P.M. Cleutjens, Tom Luedde, Drolaiz H. W. Liu, Nadine T. Gaisa, Steven W.M. Olde Damink, Xiuxiang Tan, Shivan Sivakumar, Dominik Paul Modest, Merel R. Aberle, Gregory van der Kroft, Nicole Heussen, Jakob Nikolas Kather, Jan M. Niehues

Publikováno v: Journal of Clinical Medicine
Journal of Clinical Medicine, 10(3):490. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Clinical Medicine, Vol 10, Iss 490, p 490 (2021)
Journal of Clinical Medicine 10(3), 490 (2021). doi:10.3390/jcm10030490 special issue: "Special Issue "Pancreatic Cancer: Challenges and Breakthroughs" / Special Issue Editor: Dr. Maria Del Pilar Acedo Nunez, Guest Editor"
Volume 10
Issue 3

Journal of Clinical Medicine 10(3), 490 (2021). doi:10.3390/jcm10030490 special issue: "Special Issue "Pancreatic Cancer: Challenges and Breakthroughs" / Special Issue Editor: Dr. Maria Del Pilar Acedo Nunez, Guest Editor"
Published by MDPI, Bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75919cb426fd45b38a217690148accc4
https://pubmed.ncbi.nlm.nih.gov/33573277

Nerve fibers in the Tumor Microenvironment are co-localized with Tertiary Lymphoid Structures

Autor: Ulf P. Neumann, Xiuxiang Tan, Drolaiz H. W. Liu, Nadine T. Gaisa, Shivan Sivakumar, Jan Bednarsch, Georg Wiltberger, Tom Luedde, Steven W.M. Olde Damink, Sven Arke Lang, Merel R. Aberle, Lara R. Heij, Nicole Heussen, Jack P.M. Cleutjens, Gregory van der Kroft, Jakob Nikolas Kather, Jan M. Niehues, Dominik Paul Modest

BackgroundB cells and tertiary lymphoid structures (TLS) are reported to be important in the improvement of survival of cancer patients. These secondary lymphoid organs have been associated with the generation of an anti-tumor response. Pancreatic du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7f924c66b90b17f7f0a6474071c9b7f
https://doi.org/10.1101/2020.08.07.232322