Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Driton Vllasaliu"'
Autor:
Yunyue Zhang, Mona Belaid, Xiang Luo, Armond Daci, Rinë Limani, Julia Mantaj, Matthias Zilbauer, Komal Nayak, Driton Vllasaliu
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Oral delivery remains unattainable for nucleic acid therapies. Many nanoparticle-based drug delivery systems have been investigated for this, but most suffer from poor gut stability, poor mucus diffusion and/or inefficient epithel
Externí odkaz:
https://doaj.org/article/ed155bd831e14b01891e6d065e6e7236
Autor:
Victoria Capel, Driton Vllasaliu, Peter Watts, Philip A. Clarke, Dominic Luxton, Anna M. Grabowska, Giuseppe Mantovani, Snjezana Stolnik
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 644-653 (2018)
Despite research efforts full potential of siRNA-based therapeutics has not yet been fully realized due to a need for suitable, effective delivery formulations. Here, we examine a potential of a new class of water-soluble chitosans as siRNA platform
Externí odkaz:
https://doaj.org/article/ad3a75ee9ff94b2da5cfe698843e28f1
Autor:
Driton Vllasaliu
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 611 (2021)
Non-invasive drug delivery generally refers to painless drug administration methods involving drug delivery across the biological barriers of the mucosal surfaces or the skin [...]
Externí odkaz:
https://doaj.org/article/5bbb99d89faf43febb4abe18052eb8ff
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1025 (2020)
In the last decade, biological drugs have rapidly proliferated and have now become an important therapeutic modality. This is because of their high potency, high specificity and desirable safety profile. The majority of biological drugs are peptide-
Externí odkaz:
https://doaj.org/article/19e00b7ad45e41c3bc2f064691239164
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 226 (2020)
Ingestion is the preferred way for drug administration. However, many drugs have poor oral bioavailability, warranting the use of injections. Extracellular vesicles (EVs) from cow milk have shown potential utility in improving oral drug bioavailabili
Externí odkaz:
https://doaj.org/article/5d2afabe43824d8ea76c95528f11c808
Autor:
Diego Romano Perinelli, Dezemona Petrelli, Luca Agostino Vitali, Giulia Bonacucina, Marco Cespi, Driton Vllasaliu, Gianfabio Giorgioni, Giovanni Filippo Palmieri
Publikováno v:
Pharmaceutics, Vol 11, Iss 6, p 287 (2019)
Quaternary ammonium amphiphiles are a class of compounds with a wide range of commercial and industrial uses. In the pharmaceutical field, the most common quaternary ammonium surfactant is benzalkonium chloride (BAC), which is employed as a preservat
Externí odkaz:
https://doaj.org/article/0f8548ffa3714f34a8b05f6472e1aed6
Publikováno v:
Pharmaceutics, Vol 11, Iss 7, p 298 (2019)
The aim of this study was to probe whether the transferrin (Tf) transport pathway can be exploited for intestinal delivery of nanoparticles. Tf was adsorbed on 100 nm model polystyrene nanoparticles (NP), followed by size characterisation of these sy
Externí odkaz:
https://doaj.org/article/692c212831d74f359cba90d6647e4798
Publikováno v:
Applied Sciences, Vol 9, Iss 8, p 1583 (2019)
There is a need for synthetic substrates that replicate the natural environment for in vitro intestinal models. Electrospinning is one of the most versatile and cost-effective techniques to produce nanofibrous scaffolds mimicking the basement membran
Externí odkaz:
https://doaj.org/article/fcb7e5eb66b04c6188e9a92bef59fd23
Publikováno v:
Applied Sciences, Vol 9, Iss 5, p 910 (2019)
The scaffold technology research utilizes biomimicry to produce efficient scaffolds that mimic the natural cell growth environment including the basement membrane for tissue engineering. Because the natural basement membrane is composed of fibrillar
Externí odkaz:
https://doaj.org/article/abc66f207168440caba31c149e79e557
Publikováno v:
Pharmaceutics, Vol 11, Iss 3, p 127 (2019)
Biologics have changed the management of Inflammatory Bowel Disease (IBD), but there are concerns regarding unexpected systemic toxicity and loss of therapeutic response following administration by injection. Local delivery of biologics directly to t
Externí odkaz:
https://doaj.org/article/c7f635c5e8b44119bfcdd838404bcc04