Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Driss, El Kebir"'
Autor:
Senthil Kumaran Satyanarayanan, Driss El Kebir, Soaad Soboh, Sergei Butenko, Meriem Sekheri, Janan Saadi, Neta Peled, Simaan Assi, Amira Othman, Sagie Schif-Zuck, Yonatan Feuermann, Dalit Barkan, Noa Sher, János G. Filep, Amiram Ariel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Clearance of apoptotic neutrophils by macrophages is important for the resolution of inflammation. Here, the authors show that interferon-β produced by resolution phase macrophages promotes neutrophil apoptosis and efferocytosis and induces macropha
Externí odkaz:
https://doaj.org/article/bde7b79a24f74c988fe97e64005be189
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(31)
Aberrant immune responses, including hyperresponsiveness to Toll-like receptor (TLR) ligands, underlie acute respiratory distress syndrome (ARDS). Type I interferons confer antiviral activities and could also regulate the inflammatory response, where
Autor:
Driss El Kebir, János G. Filep
Publikováno v:
Cells, Vol 2, Iss 2, Pp 330-348 (2013)
Resolution of acute inflammation is an active process that requires inhibition of further leukocyte recruitment and removal of leukocytes from inflamed sites. Emigrated neutrophils undergo apoptosis before being removed by scavenger macrophages. Rece
Externí odkaz:
https://doaj.org/article/75f3301b98c44e9493617472d0c8baa1
Publikováno v:
Proceedings of the National Academy of Sciences. 117:7971-7980
Timely resolution of bacterial infections critically depends on phagocytosis of invading pathogens by polymorphonuclear neutrophil granulocytes (PMNs), followed by PMN apoptosis and efferocytosis. Here we report that bacterial DNA (CpG DNA) and mitoc
Autor:
Driss El Kebir, János G. Filep
Publikováno v:
The Scientific World Journal, Vol 10, Pp 1731-1748 (2010)
Neutrophil granulocytes play a central role in host defense to infection and tissue injury. Their timely removal is essential for resolution of inflammation. Increasing evidence identified neutrophil apoptosis as an important control point in the dev
Externí odkaz:
https://doaj.org/article/e66221897d724df28a292dfd106db158
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87006 (2014)
Neutrophils detect bacterial constituents, including bacterial DNA (CpG DNA), which elicits innate immunity and prolongs the functional life span of neutrophils through suppression of apoptosis. Both the anti-apoptotic protein Mcl-1 and activation of
Externí odkaz:
https://doaj.org/article/dad0379a9c9d4fa182f70c5465ac9724
Publikováno v:
Proc Natl Acad Sci U S A
Timely resolution of bacterial infections critically depends on phagocytosis of invading pathogens by polymorphonuclear neutrophil granulocytes (PMNs), followed by PMN apoptosis and efferocytosis. Here we report that bacterial DNA (CpG DNA) and mitoc
Autor:
Driss El Kebir, Yonatan Feuermann, Amira Othman, Soaad Soboh, Janan Saadi, Neta Peled, Amiram Ariel, Sagie Schif-Zuck, Simaan Assi, Dalit Barkan, Noa Sher, Meriem Sekheri, János G. Filep, Sergei Butenko, Senthil Kumaran Satyanarayanan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
The uptake of apoptotic polymorphonuclear cells (PMN) by macrophages is critical for timely resolution of inflammation. High-burden uptake of apoptotic cells is associated with loss of phagocytosis in resolution phase macrophages. Here, using a trans
Publikováno v:
European journal of pharmacology. 833
The formyl peptide receptors (FPRs) are G protein coupled receptors that recognize a broad range of structurally distinct pathogen and danger-associated molecular patterns and mediate host defense to infection and tissue injury. It became evident tha
Autor:
Meriem Sekheri, Soukaina Mansouri, János G. Filep, Everton de Oliveira Lima dos Santos, Driss El Kebir
Publikováno v:
Journal of leukocyte biology. 102(6)
Accumulating evidence indicates development of local extracellular acidosis in inflamed tissues in response to infection and tissue injury. Activation of infiltrating neutrophils contributes to a transient decrease in pH, which, in turn, triggers inn