Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Driscoll JP"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 44(8)
The significant roles that cytochrome P450 (P450) and UDP-glucuronosyl transferase (UGT) enzymes play in drug discovery cannot be ignored, and these enzyme systems are commonly examined during drug optimization using liver microsomes or hepatocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ad210116fc0327c6c3f423098f97d2
https://pubmed.ncbi.nlm.nih.gov/27117704
https://pubmed.ncbi.nlm.nih.gov/27117704
Akademický článek
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Akademický článek
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Autor:
Jackson KD; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, Chapel Hill, NC, USA., Argikar UA; Non-Clinical Development, Bill & Melinda Gates Medical Research Institute, Cambridge, MA, USA., Cho S; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA., Crouch RD; Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy and Health Sciences, Nashville, TN, USA., Driscoll JP; Department of Drug Metabolism and Pharmacokinetics, Bristol Myers Squibb, Brisbane, CA, USA., Heck CJS; Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT, USA., King L; Department of DMPK, UCB Biopharma UK, Slough, UK., Maw HH; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA., Miller GP; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Seneviratne HK; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Wang S; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA., Wei C; Drug Metabolism & Pharmacokinetics, Biogen Inc., Cambridge, MA, USA., Zhang D; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA., Khojasteh SC; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA.
Publikováno v:
Drug metabolism reviews [Drug Metab Rev] 2022 Aug; Vol. 54 (3), pp. 246-281. Date of Electronic Publication: 2022 Aug 05.
Autor:
Khojasteh SC; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA., Argikar UA; Translational Medicine, Novartis Institutes for Biomedical Research, Inc., Cambridge, MA, USA., Driscoll JP; Department of Drug Metabolism and Pharmacokinetics, MyoKardia, Inc., South San Francisco, CA, USA., Heck CJS; Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT, USA., King L; Department of DMPK, UCB Biopharma, Slough, UK., Jackson KD; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, Chapel Hill, NC, USA., Jian W; Drug Metabolism and Pharmacokinetics, Janssen Research & Development, Spring House, PA, USA., Kalgutkar AS; Medicine Design, Pfizer Worldwide Research, Development and Medical, Cambridge, MA, USA., Miller GP; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA., Kramlinger V; Translational Medicine, Novartis Institutes for Biomedical Research, Inc., Cambridge, MA, USA., Rietjens IMCM; Division of Toxicology, Wageningen University, Wageningen, The Netherlands., Teitelbaum AM; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA., Wang K; Drug Metabolism and Pharmacokinetics, Janssen Research & Development, San Diego, CA, USA., Wei C; Drug Metabolism & Pharmacokinetics, Biogen Inc., Cambridge, MA, USA.
Publikováno v:
Drug metabolism reviews [Drug Metab Rev] 2021 Aug; Vol. 53 (3), pp. 384-433. Date of Electronic Publication: 2021 Jun 24.
Autor:
Grillo MP; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA., Markova S; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA.; Jazz Pharmaceuticals Inc, Palo Alto, CA, USA., Evanchik M; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA.; Drug Metabolism and Pharmacokinetics, Assembly Biosciences Inc R&D Main Facility, South San Francisco, CA, USA., Trellu M; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Chilly Mazarin, France., Moliner P; Sanofi, Montpellier, France., Brun P; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Chilly Mazarin, France., Perreard-Dumaine A; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Alfortville, France., Vicat P; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Alfortville, France., Driscoll JP; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA., Carlson TJ; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA.
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Feb; Vol. 51 (2), pp. 222-238. Date of Electronic Publication: 2020 Nov 16.
Autor:
Khojasteh SC; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc, South San Francisco, CA, USA., Driscoll JP; Department of Drug Metabolism and Pharmacokinetics, MyoKardia, Inc, South San Francisco, CA, USA., Jackson KD; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, Chapel Hill, NC, USA., Miller GP; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Mitra K; Department of Safety Assessment and Laboratory Animal Resources, Merck Research Laboratories (MRL), Merck & Co., Inc, West Point, PA, USA., Rietjens IMCM; Division of Toxicology, Wageningen University, Wageningen, The Netherlands., Zhang D; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc, South San Francisco, CA, USA.
Publikováno v:
Drug metabolism reviews [Drug Metab Rev] 2020 Aug; Vol. 52 (3), pp. 333-365. Date of Electronic Publication: 2020 Jul 09.
Autor:
Driscoll JP; MyoKardia, Inc., 333 Allerton Avenue, South San Francisco, California 94080, United States., Sadlowski CM; MyoKardia, Inc., 333 Allerton Avenue, South San Francisco, California 94080, United States., Shah NR; MyoKardia, Inc., 333 Allerton Avenue, South San Francisco, California 94080, United States., Feula A; MyoKardia, Inc., 333 Allerton Avenue, South San Francisco, California 94080, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2020 Jun 25; Vol. 63 (12), pp. 6303-6314. Date of Electronic Publication: 2020 Apr 21.
Autor:
Kalgutkar AS; Medicine Design, Pfizer Worldwide Research, Development and Medical, 1 Portland Street, Cambridge, MA 02139, United States. Electronic address: amit.kalgutkar@pfizer.com., Driscoll JP; Drug Metabolism and Pharmacokinetics, Myokardia, Inc., South San Francisco CA 94080, United States.
Publikováno v:
Biochemical pharmacology [Biochem Pharmacol] 2020 Apr; Vol. 174, pp. 113796. Date of Electronic Publication: 2020 Jan 10.
Autor:
Yadav AS; MyoKardia, Inc. , 333 Allerton Avenue , South San Francisco , California 94080 , United States., Shah NR; MyoKardia, Inc. , 333 Allerton Avenue , South San Francisco , California 94080 , United States., Carlson TJ; MyoKardia, Inc. , 333 Allerton Avenue , South San Francisco , California 94080 , United States., Driscoll JP; MyoKardia, Inc. , 333 Allerton Avenue , South San Francisco , California 94080 , United States.
Publikováno v:
Chemical research in toxicology [Chem Res Toxicol] 2020 Jan 21; Vol. 33 (1), pp. 249-257. Date of Electronic Publication: 2019 Dec 23.