Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dries Verdegem"'
Autor:
Emma L. Schymanski, Christoph Ruttkies, Martin Krauss, Céline Brouard, Tobias Kind, Kai Dührkop, Felicity Allen, Arpana Vaniya, Dries Verdegem, Sebastian Böcker, Juho Rousu, Huibin Shen, Hiroshi Tsugawa, Tanvir Sajed, Oliver Fiehn, Bart Ghesquière, Steffen Neumann
Publikováno v:
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-21 (2017)
Abstract Background The fourth round of the Critical Assessment of Small Molecule Identification (CASMI) Contest ( www.casmi-contest.org ) was held in 2016, with two new categories for automated methods. This article covers the 208 challenges in Cate
Externí odkaz:
https://doaj.org/article/013056657b734f69b3d71c7aa087fc60
Autor:
Bert Cruys, Brian W. Wong, Anna Kuchnio, Dries Verdegem, Anna Rita Cantelmo, Lena-Christin Conradi, Saar Vandekeere, Ann Bouché, Ivo Cornelissen, Stefan Vinckier, Roeland M. H. Merks, Elisabetta Dejana, Holger Gerhardt, Mieke Dewerchin, Katie Bentley, Peter Carmeliet
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Glycolytic regulator PFKFB3 is a key player in vessel sprouting. Here the authors develop a computational model predicting that PFKFB3 drives endothelial cell rearrangement during vessel sprouting by promoting filopodia formation and reducing interce
Externí odkaz:
https://doaj.org/article/f168b79c697d4569b921c383b7c0a3c0
© 2017, Springer Science+Business Media, LLC. Introduction: Metabolic tracer analysis (MTA) is a collection of principles, rules and tools for the interpretation of stable isotope incorporation patterns. One example is the GAIMS algorithm for the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f243bef36e32d41a37de5d2dbe8321
https://lirias.kuleuven.be/handle/123456789/595600
https://lirias.kuleuven.be/handle/123456789/595600
© 2016, Springer Science+Business Media New York. Introduction: LC–MS/MS based untargeted metabolomics is evoking high interests in the metabolomics and broader biology community for its potential to uncover the contribution of unanticipated metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b5c04e94406172688ce19e786f6d30
https://lirias.kuleuven.be/handle/123456789/567677
https://lirias.kuleuven.be/handle/123456789/567677
Autor:
Don W. Cleveland, Tom Dresselaers, Bert Cruys, Matt S. Ramer, Annelies Quaegebeur, Gene Hung, Goele Bossaert, Carla De Legher, Sarah-Maria Fendt, Ann Bouché, Bart Ghesquière, Roberta Schmieder, Peter Carmeliet, Inmaculada Segura, Francesco Bifari, Guy Eelen, Ilaria Decimo, Mieke Dewerchin, Wim Robberecht, Kristof Govaerts, Shawn M. Davidson, Robin Lemmens, Dorien Broekaert, Sandra Schoors, Debapriya Ghosh, Luc Schoonjans, Dries Verdegem, C. Frank Bennett, Katrien De Bock, Uwe Himmelreich, Thomas Voets
Publikováno v:
Cell metabolism, vol 23, iss 2
The oxygen-sensing prolyl hydroxylase domain proteins (PHDs) regulate cellular metabolism, but their role in neuronal metabolism during stroke is unknown. Here we report that PHD1 deficiency provides neuroprotection in a murine model of permanent bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a884fee9094d0ee1fa61c7703b48c2c6
https://lirias.kuleuven.be/handle/123456789/525591
https://lirias.kuleuven.be/handle/123456789/525591
Autor:
Saar Vandekeere, Brian W. Wong, Stefan Vinckier, Elisabetta Dejana, Peter Carmeliet, Holger Gerhardt, Anna Rita Cantelmo, Anna Kuchnio, Lena Christin Conradi, Ann Bouché, Mieke Dewerchin, Roeland M. H. Merks, Katie Bentley, Bert Cruys, Ivo Cornelissen, Dries Verdegem
Publikováno v:
Nature Communications
Nature Communications, 7
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Cruys, B, Wong, B W, Kuchnio, A, Verdegem, D, Cantelmo, A R, Conradi, L C, Vandekeere, S, Bouche, A, Cornelissen, I, Vinckier, S, Merks, R M H, Dejana, E, Gerhardt, H, Dewerchin, M, Bentley, K & Carmeliet, P 2016, ' Glycolytic regulation of cell rearrangement in angiogenesis ', Nature Communications, vol. 7, 12240, pp. 1-15 . https://doi.org/10.1038/ncomms12240
Nature Communications, 7, 12240. Nature Research
Nature Communications, 7
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Cruys, B, Wong, B W, Kuchnio, A, Verdegem, D, Cantelmo, A R, Conradi, L C, Vandekeere, S, Bouche, A, Cornelissen, I, Vinckier, S, Merks, R M H, Dejana, E, Gerhardt, H, Dewerchin, M, Bentley, K & Carmeliet, P 2016, ' Glycolytic regulation of cell rearrangement in angiogenesis ', Nature Communications, vol. 7, 12240, pp. 1-15 . https://doi.org/10.1038/ncomms12240
Nature Communications, 7, 12240. Nature Research
During vessel sprouting, endothelial cells (ECs) dynamically rearrange positions in the sprout to compete for the tip position. We recently identified a key role for the glycolytic activator PFKFB3 in vessel sprouting by regulating cytoskeleton remod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442049ab968786f0578b091ccd06c573
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-302709
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-302709
Autor:
Nathalie Sibille, Dries Verdegem, Laziza Amniai, Jean-Michel Wieruszeski, Guy Lippens, Caroline Fauquant, Isabelle Landrieu, Isabelle Huvent, Arnaud Leroy
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 80:454-462
Phosphorylation of the neuronal Tau protein is implicated in both the regulation of its physiological function of microtubule stabilization and its pathological propensity to aggregate into the fibers that characterize Alzheimer's diseased neurons. H
Autor:
Ralf Bartenschlager, Xavier Hanoulle, Guy Lippens, Aurélie Badillo, Jean-Michel Wieruszeski, François Penin, Isabelle Landrieu, Dries Verdegem
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
Journal of Biological Chemistry, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
Journal of Biological Chemistry, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
International audience; We report a biochemical and structural characterization of domain 2 of the non-structural 5A protein (NS5A) from the JFH1 Hepatitis C virus strain and its interactions with Cyclophilins A and B (CypA and CypB). Gel filtration
Publikováno v:
Cancer & Metabolism
The stromal vasculature in tumors is a vital conduit of nutrients and oxygen for cancer cells. To date, the vast majority of studies have focused on unraveling the genetic basis of vessel sprouting (also termed angiogenesis). In contrast to the widel
Autor:
Olivier Laprévote, Jean-Michel Wieruszeski, Guy Lippens, Virginie Redeker, Dries Verdegem, Caroline Fauquant, Marcel Knossow, Benoît Gigant, Isabelle Landrieu
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2011, epub ahead of print. ⟨10.1074/jbc.M111.223545⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, epub ahead of print. ⟨10.1074/jbc.M111.223545⟩
Journal of Biological Chemistry, 2011, epub ahead of print. ⟨10.1074/jbc.M111.223545⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, epub ahead of print. ⟨10.1074/jbc.M111.223545⟩
International audience; Tau is a microtubule-associated protein which stabilizes microtubules and stimulates their assembly. Current descriptions of the tubulin-interacting regions of Tau involve microtubules as the target and result mainly from dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8e9aa46e51a20977458a649eba9253
https://hal.science/hal-00618268
https://hal.science/hal-00618268