Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Driele N. Garcia"'
Autor:
Jessica D. Hense, Driele N. Garcia, Bianka M. Zanini, Mariana M. Barreto, Giulia C. Perreira, José V. V. Isola, Camila de Brito, Michal Fornalik, Samim A. Mondal, Bianca M. Ávila, Thais L. Oliveira, Heather C. Rice, Charles I. Lacy, Rodrigo A. Vaucher, Jeffrey B. Mason, Michal M. Masternak, Michael B. Stout, Augusto Schneider
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Senescent cells have been linked to the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD). However, the effectiveness of senolytic drugs in reducing liver damage in mice with MASLD is not clear. Additionally, M
Externí odkaz:
https://doaj.org/article/326ef71c5c2c449693e78d894c2773a5
Autor:
Driele N. Garcia, Jéssica D. Hense, Bianka M. Zanini, José V. V. Isola, Jorgea Pradiee, Juliane B. Prosczek, Joao A. Alvarado-Rincón, Rafael G. Mondadori, Jeffrey B. Mason, Miguel A. Brieño-Enríquez, Carlos C. Barros, Michael B. Stout, Michal M. Masternak, Augusto Schneider
Publikováno v:
Physiology International.
Cellular senescence is a defense mechanism to arrest proliferation of damaged cells. The number of senescent cells increases with age in different tissues and contributes to the development of age-related diseases. Old mice treated with senolytics dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ab4ad7dd0b25a9f514218679f3d6556
https://doi.org/10.1556/2060.2023.00192
https://doi.org/10.1556/2060.2023.00192
Autor:
Jéssica D. Hense, Driele N. Garcia, José V. Isola, Joao A. Alvarado-Rincón, Bianka M. Zanini, Juliane B. Prosczek, Michael B. Stout, Jeffrey B. Mason, Patrick T. Walsh, Miguel A. Brieño-Enríquez, Ines Schadock, Carlos C. Barros, Michal M. Masternak, Augusto Schneider
Publikováno v:
GeroScience
Senescent cells are in a cell cycle arrest state and accumulate with aging and obesity, contributing to a chronic inflammatory state. Treatment with senolytic drugs dasatinib and quercetin (D + Q) can reduce senescent cell burden in several tissues,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a38843b8d70f0f61abb6e189194b5a
https://doi.org/10.1007/s11357-022-00573-9
https://doi.org/10.1007/s11357-022-00573-9
Autor:
José V. V. Isola, Gabriel B. Veiga, Camila R. C. de Brito, Joao A. Alvarado-Rincón, Driele N. Garcia, Bianka M. Zanini, Jéssica D. Hense, Arnaldo D. Vieira, Michael Garratt, Bernardo G. Gasperin, Augusto Schneider, Michael B. Stout
Publikováno v:
GeroScience.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339bebe7fd1c716fff4647bb189a2433
https://doi.org/10.1007/s11357-022-00601-8
https://doi.org/10.1007/s11357-022-00601-8
Autor:
Tatiana D. Saccon, Augusto Schneider, Jeffrey B. Mason, Bianka M Zanini, Driele N Garcia, Andrzej Bartke, Michael B. Stout, Marcelo Borges Cavalcante, José Victor Vieira Isola, Michal M. Masternak, Joao Alveiro Alvarado-Rincón, Jessica Damé Hense
Publikováno v:
J Gerontol A Biol Sci Med Sci
The mammalian female is born with a limited ovarian reserve of primordial follicles. These primordial follicles are slowly activated throughout the reproductive lifecycle, thereby determining lifecycle length. Once primordial follicles are exhausted,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c0b0c6f04a7834aed9df049148028a
https://doi.org/10.1093/gerona/glaa258
https://doi.org/10.1093/gerona/glaa258
Autor:
Driele N Garcia, Joao Alveiro Alvarado Rincón, Jeffrey B. Mason, Michal M. Masternak, Luis A. X. Cruz, Rafael Gianella Mondadori, Monique Tomazele Rovani, Andrzej Bartke, Kelvin R. S. Andrade, Tatiana D. Saccon, Jorgea Pradieé, Carlos Castilho Barros, Augusto Schneider
Publikováno v:
GeroScience. 41:395-408
Caloric restriction (CR) increases the preservation of the ovarian primordial follicular reserve, which can potentially delay menopause. Rapamycin also increases preservation on the ovarian reserve, with similar mechanism to CR. Therefore, the aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dd64509c168b740919947b7bc09a15
https://doi.org/10.1007/s11357-019-00087-x
https://doi.org/10.1007/s11357-019-00087-x
Autor:
Andrzej Bartke, Tatiana D. Saccon, Samuel McFadden, Driele N Garcia, Luis A. X. Cruz, Yimin Fang, Carlos Castilho Barros, Rafael Gianella Mondadori, Michal M. Masternak, Augusto Schneider, Monique Tomazele Rovani, Jeffrey B. Mason, Jorgea Pradieé
Publikováno v:
GeroScience
Evidence points to an important role of the growth hormone (GH) in the aging process and longevity. GH-deficient mice are smaller, live longer than normal littermates, and females have an increased ovarian reserve. The aim of the study was to evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0184148533cd828ef71871af100f8174
https://pubmed.ncbi.nlm.nih.gov/33954912
https://pubmed.ncbi.nlm.nih.gov/33954912
Autor:
José V.V. Isola, Bianka M. Zanini, Jessica D. Hense, Joao A. Alvarado-Rincón, Driele N. Garcia, Giulia C. Pereira, Arnaldo D. Vieira, Thais L. Oliveira, Tiago Collares, Bernardo G. Gasperin, Michael B. Stout, Augusto Schneider
Publikováno v:
Exp Gerontol
Calorie restriction (CR) (25–40%) is the most commonly studied strategy for curtailing age-related disease and has also been found to extend reproductive lifespan in female mice. However, the effects of mild CR (10%), which is sustainable, on ovari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa8af832d02ade68dbf32efc96821fc
https://doi.org/10.1016/j.exger.2021.111669
https://doi.org/10.1016/j.exger.2021.111669
Autor:
Renata Pereira Ramirez, Augusto Schneider, Gabriel Barreto Veiga, Tatiana D. Saccon, Bianka M Zanini, Michal M. Masternak, Driele N Garcia, Rafael Gianella Mondadori, Luis A. X. Cruz, Carlos Castilho Barros, Joao Alveiro Alvarado-Rincón, Kelvin R. S. Andrade, Jorgea Pradieé
Publikováno v:
Reproduction, fertility, and development. 32(18)
The aim of this study was to investigate the effect of calorie restriction (CR) during pregnancy in mice on metabolism and ovarian function in the offspring. Pregnant female mice were divided into two groups, a control group and a CR group (n=7 in ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c93ca257336b6cf6031f2326f5dcf77
https://pubmed.ncbi.nlm.nih.gov/33243369
https://pubmed.ncbi.nlm.nih.gov/33243369
Autor:
Luis A. X. Cruz, Augusto Schneider, Andrzej Bartke, Rafael Gianella Mondadori, Carlos Castilho Barros, Tatiana D. Saccon, Monique Tomazele Rovani, Driele N Garcia, Michal M. Masternak
Publikováno v:
Exp Gerontol
The aim of this study was to evaluate the effect of growth hormone (GH) deficiency in primordial follicle reserve, DNA damage and macrophage infiltration in the ovaries of young mice. Ovaries from six-month-old GH-deficient Ames Dwarf (df/df) and Nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e96245aceca7534e25fd2ba2f4f0073
https://europepmc.org/articles/PMC7025715/
https://europepmc.org/articles/PMC7025715/
