Enhancing fatty acid and omega-3 production in Schizochytrium sp. using developed safe-harboring expression system.

Autor: Ryu, Ae Jin¹ (AUTHOR), Shin, Won-Sub¹ (AUTHOR), Jang, Sunghoon¹ (AUTHOR), Lin, Yejin² (AUTHOR), Park, Yejee² (AUTHOR), Choi, Yujung² (AUTHOR), Kim, Ji Young¹ (AUTHOR) jy.kim2@cj.net, Kang, Nam Kyu² (AUTHOR) nkkang@khu.ac.kr

Publikováno v: Journal of Biological Engineering. 10/10/2024, Vol. 18 Issue 1, p1-11. 11p.

Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.

Autor: Slade DJ; †Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States.; ¶Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States., Fang P; ‡Department of Cancer Biology, The Scripps Research Institute, Jupiter, Florida 33458, United States., Dreyton CJ; †Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States.; ∇Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Zhang Y; §Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, United States., Fuhrmann J; †Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States., Rempel D; §Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, United States., Bax BD; ∥Molecular Discovery Research, GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage, Herts., SG1 2NY, United Kingdom., Coonrod SA; ⊥Department of Biomedical Sciences, Baker Institute for Animal Health, Cornell University, Ithaca, New York 14853, United States., Lewis HD; #EpiNova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage, Herts., SG1 2NY, United Kingdom., Guo M; ‡Department of Cancer Biology, The Scripps Research Institute, Jupiter, Florida 33458, United States., Gross ML; §Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, United States., Thompson PR; †Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States.; ∇Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2015 Apr 17; Vol. 10 (4), pp. 1043-53. Date of Electronic Publication: 2015 Jan 26.

Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism.

Autor: Dreyton CJ; Department of Chemistry and The Kellogg School of Graduate Studies, The Scripps Research Institute-Florida , 130 Scripps Way, Jupiter, Florida 33458, United States., Knuckley B, Jones JE, Lewallen DM, Thompson PR

Publikováno v: Biochemistry [Biochemistry] 2014 Jul 15; Vol. 53 (27), pp. 4426-33. Date of Electronic Publication: 2014 Jul 03.

Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation.

Autor: Zhang X; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Aug 14; Vol. 109 (33), pp. 13331-6. Date of Electronic Publication: 2012 Aug 01.

Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

Autor: Knuckley B; Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, South Carolina 29208, USA., Causey CP, Jones JE, Bhatia M, Dreyton CJ, Osborne TC, Takahara H, Thompson PR

Publikováno v: Biochemistry [Biochemistry] 2010 Jun 15; Vol. 49 (23), pp. 4852-63.