Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Drew R Jones"'
Autor:
Julie Trolle, Ross M McBee, Andrew Kaufman, Sudarshan Pinglay, Henri Berger, Sergei German, Liyuan Liu, Michael J Shen, Xinyi Guo, J Andrew Martin, Michael E Pacold, Drew R Jones, Jef D Boeke, Harris H Wang
Publikováno v:
eLife, Vol 11 (2022)
Major genomic deletions in independent eukaryotic lineages have led to repeated ancestral loss of biosynthesis pathways for nine of the twenty canonical amino acids. While the evolutionary forces driving these polyphyletic deletion events are not wel
Externí odkaz:
https://doaj.org/article/f7739089fa7b4affac08a2193ca55419
Autor:
Lynne Chantranupong, Jessica L Saulnier, Wengang Wang, Drew R Jones, Michael E Pacold, Bernardo L Sabatini
Publikováno v:
eLife, Vol 9 (2020)
Neurons communicate by the activity-dependent release of small-molecule neurotransmitters packaged into synaptic vesicles (SVs). Although many molecules have been identified as neurotransmitters, technical limitations have precluded a full metabolomi
Externí odkaz:
https://doaj.org/article/d6079662b5df464a9044491aa0a94a6d
Autor:
David M Curran, Alexandra Grote, Nirvana Nursimulu, Adam Geber, Dennis Voronin, Drew R Jones, Elodie Ghedin, John Parkinson
Publikováno v:
eLife, Vol 9 (2020)
The filarial nematode Brugia malayi represents a leading cause of disability in the developing world, causing lymphatic filariasis in nearly 40 million people. Currently available drugs are not well-suited to mass drug administration efforts, so new
Externí odkaz:
https://doaj.org/article/237b052a1e164d3ba8cba9fbc09f1259
Autor:
Gustavo Morrone Parfitt, Elena Coccia, Camille Goldman, Kristen Whitney, Ricardo Reyes, Lily Sarrafha, Ki Hong Nam, Soha Sohail, Drew R. Jones, John F. Crary, Alban Ordureau, Joel Blanchard, Tim Ahfeldt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Accumulation of advanced glycation end products (AGEs) on biopolymers accompanies cellular aging and drives poorly understood disease processes. Here, we studied how AGEs contribute to development of early onset Parkinson’s Disease (PD) ca
Externí odkaz:
https://doaj.org/article/445ece7c4baa4fb2866187e8b98ff91d
Autor:
Niklas Ravn-Boess, Nainita Roy, Takamitsu Hattori, Devin Bready, Hayley Donaldson, Christopher Lawson, Cathryn Lapierre, Aryeh Korman, Tori Rodrick, Enze Liu, Joshua D. Frenster, Gabriele Stephan, Jordan Wilcox, Alexis D. Corrado, Julia Cai, Rebecca Ronnen, Shuai Wang, Sara Haddock, Jonathan Sabio Ortiz, Orin Mishkit, Alireza Khodadadi-Jamayran, Aris Tsirigos, David Fenyö, David Zagzag, Julia Drube, Carsten Hoffmann, Fabiana Perna, Drew R. Jones, Richard Possemato, Akiko Koide, Shohei Koide, Christopher Y. Park, Dimitris G. Placantonakis
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113374- (2023)
Summary: Glioblastoma (GBM) is the most common and aggressive primary brain malignancy. Adhesion G protein-coupled receptors (aGPCRs) have attracted interest for their potential as treatment targets. Here, we show that CD97 (ADGRE5) is the most promi
Externí odkaz:
https://doaj.org/article/e954f101e34e4454841a124bf6a6e405
Autor:
Bora E. Baysal, Abdulrahman A. Alahmari, Tori C. Rodrick, Debra Tabaczynski, Leslie Curtin, Mukund Seshadri, Drew R. Jones, Sandra Sexton
Publikováno v:
JCI Insight, Vol 7, Iss 17 (2022)
Increased red cell distribution width (RDW), which measures erythrocyte mean corpuscular volume (MCV) variability (anisocytosis), has been linked to early mortality in many diseases and in older adults through unknown mechanisms. Hypoxic stress has b
Externí odkaz:
https://doaj.org/article/6e386b37317743b7bd8dc77fb128af7f
Autor:
Royce W. Zhou, Jia Xu, Tiphaine C. Martin, Alexis L. Zachem, John He, Sait Ozturk, Deniz Demircioglu, Ankita Bansal, Andrew P. Trotta, Bruno Giotti, Berkley Gryder, Yao Shen, Xuewei Wu, Saul Carcamo, Kaitlyn Bosch, Benjamin Hopkins, Alexander Tsankov, Randolph Steinhagen, Drew R. Jones, John Asara, Jerry E. Chipuk, Rachel Brody, Steven Itzkowitz, Iok In Christine Chio, Dan Hasson, Emily Bernstein, Ramon E. Parsons
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/9c2c6cb8439a47878da63f05bb8f178d
Publikováno v:
Viruses, Vol 15, Iss 1, p 242 (2023)
Influenza represents a major and ongoing public health hazard. Current collaborative efforts are aimed toward creating a universal flu vaccine with the goals of both improving responses to vaccination and increasing the breadth of protection against
Externí odkaz:
https://doaj.org/article/1819d34de0f74dc89203147f80914591
Autor:
Mia J. Coleman, Luis M. Espino, Hernan Lebensohn, Marija V. Zimkute, Negar Yaghooti, Christina L. Ling, Jessica M. Gross, Natalia Listwan, Sandra Cano, Vanessa Garcia, Debbie M. Lovato, Susan L. Tigert, Drew R. Jones, Rama R. Gullapalli, Neal E. Rakov, Euriko G. Torrazza Perez, Eliseo F. Castillo
Publikováno v:
Metabolites, Vol 12, Iss 5, p 431 (2022)
Background: Metabolic Syndrome (MetS) is a clinical diagnosis where patients exhibit three out of the five risk factors: hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol, hyperglycemia, elevated blood pressure, or increased abdomi
Externí odkaz:
https://doaj.org/article/a048b348431a4d2e81e28cdc42acbb6f
Autor:
Dominique F. Leitner, Yik Siu, Aryeh Korman, Ziyan Lin, Evgeny Kanshin, Daniel Friedman, Sasha Devore, Beatrix Ueberheide, Aristotelis Tsirigos, Drew R. Jones, Thomas Wisniewski, Orrin Devinsky
Publikováno v:
Epilepsia. 64:1046-1060