Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Drew Nicholas Wilfahrt"'
Autor:
Drew Nicholas Wilfahrt, Rachael Philips, Monika Kizerwetter, Jyoti K Lama, Matthew Rajcula, Madeleine Kennedy, Virginia Smith Shapiro
Publikováno v:
The Journal of Immunology. 206:24.15-24.15
After activation, CD4+ T cells undergo metabolic modifications in order to orchestrate successful immune responses. In particular, naïve T cells shift to a more glycolysis-heavy metabolic program that produces the necessary metabolites for growth, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a1e4ba98cf969ac79a16dc6a65ed524
https://doi.org/10.4049/jimmunol.206.supp.24.15
https://doi.org/10.4049/jimmunol.206.supp.24.15
Publikováno v:
The Journal of Immunology. 202:56.15-56.15
T cell anergy is a state of cellular hyporesponsiveness that prevents the propagation of an immune response to self. Consequently, the development and maintenance of the anergy program in T cells is tightly controlled. We found in wild type (WT) mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d350ca9ca9541e30ba4243dcbd63e8f9
https://doi.org/10.4049/jimmunol.202.supp.56.15
https://doi.org/10.4049/jimmunol.202.supp.56.15
Autor:
Drew Nicholas Wilfahrt, Fan-Chi Hsu, Julia Chung, Sinibaldo Romero Arocha, Aaron Schwab, Virginia Smith Shapiro
Publikováno v:
The Journal of Immunology. 200:47.10-47.10
The transcription factor Runx1 is critical for T cell development and maturation. CD4-Cre Runx1 conditional knockout mice have a block in T cell maturation, leading to complement deposition on CD4+ recent thymic emigrants, leaving very few CD4+ T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d5364309d6c3b1b46b65b3f55f62e8
https://doi.org/10.4049/jimmunol.200.supp.47.10
https://doi.org/10.4049/jimmunol.200.supp.47.10