Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Drew Nannini"'
Autor:
Lifang Hou, Andrea Baccarelli, Joel Schwartz, Pantel Vokonas, Jincheng Shen, Mirjam Hoxha, Lewis R. Roberts, Chad J. Achenbach, Hushan Yang, Robert Murphy, Masha Kocherginsky, Tao Gao, Lei Liu, Zhou Zhang, Drew Nannini, Yinan Zheng, Brian T. Joyce
Table S1: Detailed information on all CpGs of interest Table S2: Cancer-associated CpGs in TRGs by pathway at FDR < 0.05, with unspecified skin malignancies excluded Table S3: Methylation trajectory over time by cancer status Table S4: Logistic regre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422773061fc77a8a57b2610a345734d6
https://doi.org/10.1158/1940-6207.22533701
https://doi.org/10.1158/1940-6207.22533701
Autor:
Philip Greenland, Kiang Liu, David R. Jacobs, Yinan Zheng, Myron D. Gross, Lifang Hou, Lei Liu, Hongyan Ning, Amy Krefman, Daniel Levy, Donald M. Lloyd-Jones, Brian T. Joyce, Pamela J. Schreiner, Norrina B. Allen, Ake T. Lu, Cora E. Lewis, James M. Shikany, Shih-Jen Hwang, Steve Horvath, Jiantao Ma, Stephen Sidney, Drew Nannini, Tao Gao
Publikováno v:
Circ Res
Rationale: Epigenetic aging is a novel measure of biological age, reflecting exposures and disease risks independent of chronological age. It may serve as a useful biomarker of cardiovascular health (CVH) or cardiovascular disease risk for early dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6113c54c7dab4df89f9ae19d5dd47367
https://doi.org/10.1161/circresaha.121.318965
https://doi.org/10.1161/circresaha.121.318965
Autor:
Yun Shen, Huikun Liu, Stephanie Shiau, Leishen Wang, Jun Wang, Weiqin Li, Ru Gao, Andrea A. Baccarelli, Lifang Hou, Yinan Zheng, Brian T. Joyce, Alexander W. Drong, Junhong Leng, Gang Hu, Drew Nannini
Publikováno v:
Epigenomics
Background & objectives: Examine maternal gestational diabetes mellitus (GDM), macrosomia and DNA methylation in candidate genes IGF1, IGF2, H19, ARHGRF11, MEST, NR3C1, ADIPOQ and RETN. Materials & methods: A total of 1145 children (572 GDM cases and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c4ff45adcefb5ff71e83ae48a3e842
https://europepmc.org/articles/PMC8371577/
https://europepmc.org/articles/PMC8371577/
Autor:
Fredrick Otieno, Lifang Hou, Supriya D. Mehta, Stefan J. Green, Walter Agingu, Yinan Zheng, Alan L. Landay, Drew Nannini
Publikováno v:
mSystems, Vol 5, Iss 4, p e00502-20 (2020)
mSystems, Vol 5, Iss 4 (2020)
mSystems
mSystems, Vol 5, Iss 4 (2020)
mSystems
Globally, bacterial vaginosis (BV) is a common condition in women. BV is associated with poorer reproductive health outcomes and HIV risk. Typically, BV represents a shift in the vaginal microbiome from one that is dominated by Lactobacillus to one t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6933de1362154fbeca404db5cbdc04f1
https://doaj.org/article/d66830f862a44a71a169cc472aa74e4c
https://doaj.org/article/d66830f862a44a71a169cc472aa74e4c
Autor:
Laura Rasmuseen-Torvik, Lifang Hou, Donald M. Lloyd-Jones, Yinan Zheng, Yishu Qu, Sadiya S. Khan, Clyde W. Yancy, Sanjiv J. Shah, Drew Nannini, Arjun Sinha
Publikováno v:
Circulation. 141
Introduction: Direct-to-consumer testing (e.g. 23andme) reports now include common pathogenic variants in the transthyretin (TTR) gene, such as V122I. TTR cardiac amyloidosis due to V122I is an autosomal dominant disease known to be of variable penet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75fbd20b9474d3596061a3bfb9cc7f2
https://doi.org/10.1161/circ.141.suppl_1.24
https://doi.org/10.1161/circ.141.suppl_1.24
Autor:
Chad J. Achenbach, Brian T. Joyce, Yinan Zheng, Joel Schwartz, Robert L. Murphy, Lewis R. Roberts, Zhou Zhang, Lei Liu, Masha Kocherginsky, Hushan Yang, Lifang Hou, Jincheng Shen, Andrea A. Baccarelli, Drew Nannini, Pantel S. Vokonas, Tao Gao, Mirjam Hoxha
Publikováno v:
Cancer Prevention Research. 11:511-522
Researchers hypothesized that telomere shortening facilitates carcinogenesis. Previous studies found inconsistent associations between blood leukocyte telomere length (LTL) and cancer. Epigenetic reprogramming of telomere maintenance mechanisms may h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21e47a6c5efdfc6a3e6c4e722a8e507
https://doi.org/10.1158/1940-6207.capr-17-0413
https://doi.org/10.1158/1940-6207.capr-17-0413
Autor:
Jiantao Ma, Steve Horvath, Brian T. Joyce, Yinan Zheng, John T. Wilkins, Lei Liu, Sadiya S. Khan, David R. Jacobs, Donald M. Lloyd-Jones, Lifang Hou, Tianxiao Huan, Kai Zhang, Philip Greenland, Norrina B. Allen, Jim Ren, Drew Nannini, Grace Yoon, Tao Gao
Publikováno v:
Clinical Epigenetics
Background The metabolic syndrome (MetS) is a collection of metabolic disturbances that can lead to various cardiovascular diseases. Previous studies have shown a more adverse metabolic risk profile is associated with more advanced biological aging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86814900ca8e1db49f76ab52417a4e9e
https://doi.org/10.1186/s13148-019-0767-1
https://doi.org/10.1186/s13148-019-0767-1
Autor:
Ryan A. Hlady, Robert L. Murphy, Drew Nannini, Warren A. Kibbe, Yinan Zheng, Lewis R. Roberts, Chunyan He, Brian T. Joyce, Chad J. Achenbach, Lifang Hou, Keith D. Robertson
Publikováno v:
Clinical Epigenetics
Background The two most common repetitive elements (REs) in humans, long interspersed nuclear element-1 (LINE-1) and Alu element (Alu), have been linked to various cancers. Hepatitis C virus (HCV) may cause hepatocellular carcinoma (HCC) by suppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0d368053d669369c9bc24ef2fdf76f
https://doi.org/10.1186/s13148-019-0733-y
https://doi.org/10.1186/s13148-019-0733-y
Autor:
Weiqin Li, Leishen Wang, Ru Gao, Brian T. Joyce, Yun Shen, Yinan Zheng, Jun Wang, Drew Nannini, Andrea A. Baccarelli, Junhong Leng, Stephanie Shiau, Gang Hu, Alex Drong, Huikun Liu, Lifang Hou
Publikováno v:
Circulation. 139
Background: Gestational diabetes mellitus (GDM) is a known risk factor for macrosomia, with recent estimates suggesting that between 15-45% of newborns of mothers with GDM are macrosomic (vs. 12% in non-GDM mothers). This study’s objectives were to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0171d53b0dfa708587334de4827ce4b2
https://doi.org/10.1161/circ.139.suppl_1.p073
https://doi.org/10.1161/circ.139.suppl_1.p073
Autor:
Drew Nannini, Sadiya S. Khan, Elizabeth M. McNally, Donald M. Lloyd-Jones, Arjun Sinha, Lifang Hou, Laura J. Rasmussen-Torvik, Myriam Fornage, Yishu Qu, Sanjiv J. Shah, Joao A.C. Lima, Clyde W. Yancy, Yinan Zheng
Publikováno v:
JAMA Cardiol
IMPORTANCE: The variant V122I is commonly enriched in the transthyretin (TTR) gene in individuals of African ancestry and associated with greater risk of heart failure (HF) in older adulthood, after age 65 years. Prevention of HF may be most effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69784c48399ca4bf5806df10e96855a
https://doi.org/10.1001/jamacardio.2020.6623
https://doi.org/10.1001/jamacardio.2020.6623