Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Drew M, Titmarsh"'
Autor:
Jamie Trott, Ee Kim Tan, Sheena Ong, Drew M. Titmarsh, Simon L.I.J. Denil, Maybelline Giam, Cheng Kit Wong, Jiaxu Wang, Mohammad Shboul, Michelle Eio, Justin Cooper-White, Simon M. Cool, Giulia Rancati, Lawrence W. Stanton, Bruno Reversade, N. Ray Dunn
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1675-1688 (2017)
Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit considerable v
Externí odkaz:
https://doaj.org/article/420b4b50331549cead36ed5ee5db165a
Autor:
Dmitry A. Ovchinnikov, Drew M. Titmarsh, Patrick R.J. Fortuna, Alejandro Hidalgo, Samah Alharbi, Deanne J. Whitworth, Justin J. Cooper-White, Ernst J. Wolvetang
Publikováno v:
Stem Cell Research, Vol 13, Iss 2, Pp 251-261 (2014)
Optimization of pluripotent stem cell expansion and differentiation is facilitated by biological tools that permit non-invasive and dynamic monitoring of pluripotency, and the ability to select for an undifferentiated input cell population. Here we r
Externí odkaz:
https://doaj.org/article/d7ed9f79b774455283e162555ff5e793
Publikováno v:
Stem Cells and Development. 28:1347-1364
The ability of human stem cells to generate somatic cell lineages makes them ideal candidates for use in toxicological testing and eventually, preclinical drug development. Such resources would support an evolution away from human primary cells or re
Autor:
Cameron Bishop, Kathy Karavendzas, Kamil A. Sokolowski, Brian W.C. Tse, Brendan Griffen, Rajeev Rudraraju, Wei Zhao, Norman C.W. Wong, Charley Mackenzie-Kludas, Kelli P. A. MacDonald, Thuy T. Le, Sophie Krumeich, Gregory A. Quaife-Ryan, Leo J. Lee, Richard J. Mills, David A. Elliott, Stephen J. Nicholls, Holly K. Voges, Christian R. Engwerda, Daniel J. Rawle, Andreas Suhrbier, Li Fu, Jan Johansson, Rebecca L Johnston, Kanta Subbarao, Sean J. Humphrey, Mary Lor, James H McMahon, Enzo R. Porrello, Dad Abu-Bonsrah, Ewelina Kulikowski, Patrick R. J. Fortuna, Lynn Devilee, James E. Hudson, Tobias Bald, Troy Dumenil, Ellen Mathieson, Liam T Reynolds, David E. James, Michael O. Sweeney, Simon R. Foster, Drew M. Titmarsh, Christopher Halliday, Neda R Mehdiabadi, Dean Gilham, Mark J. Smyth
Publikováno v:
Cell
Cardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality. Causes are ill defined, but could be direct cardiac infection and/or inflammation-induced dysfunction. To identify mechanisms and cardio-protective drugs, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8980f221c915141159a88aa5bcdc235
https://hdl.handle.net/2123/24826
https://hdl.handle.net/2123/24826
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82931 (2013)
Cellular microenvironmental conditions coordinate to regulate stem cell populations and their differentiation. Mesenchymal precursor cells (MPCs), which have significant potential for a wide range of therapeutic applications, can be expanded or diffe
Externí odkaz:
https://doaj.org/article/4710c2ae226247b19bd358b2ad0d1c00
Autor:
Christopher Halliday, Kamil A. Sokolowski, Sophie Krumeich, David A. Elliott, Lynn Devilee, Sean J. Humphrey, Tobias Bald, Brian W.C. Tse, Gregory A. Quaife-Ryan, Leo J. Lee, Mark J. Smyth, David E. James, Rebecca L Johnston, Kanta Subbarao, Holly K. Voges, Richard J. Mills, Michael O. Sweeney, Liam T Reynolds, Stephen J. Nicholls, Mary Lor, Charley Mackenzie-Kludas, Li Fu, Jan Johansson, Kelli P. A. MacDonald, Partrick Rj Fortuna, Troy Dumenil, Norman C.W. Wong, Daniel J. Rawle, Brendan Griffen, Dad Abu-Bonsrah, Ellen Mathieson, Kathy Karavendzas, Neda R Mehdiabadi, Christian R. Engwerda, James E. Hudson, Rajeev Ruraraju, Dean Gilham, Andreas Suhrbier, Wei Zhao, Ewelina Kulikowski, Enzo R. Porrello, Simon R. Foster, Drew M. Titmarsh, Cameron Bishop, James H McMahon, Thuy T. Le
SUMMARYCardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality. Causes are ill defined, but could be direct cardiac infection and/or inflammation-induced dysfunction. To identify mechanisms and cardio-protective d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55141bf86d24196d81d19581a83309e
https://doi.org/10.1101/2020.08.23.258574
https://doi.org/10.1101/2020.08.23.258574
Autor:
Minoru Takasako, Alejandro Hidalgo, Ernst J. Wolvetang, Justin J. Cooper-White, Nick R. Glass, Melissa H. Little, Drew M. Titmarsh, Pei Xuan Er
Publikováno v:
Science Advances
Multivariate patterning of perfused pluripotent cells reveals critical roles of induced paracrine factors in kidney organoids.
Creating complex multicellular kidney organoids from pluripotent stem cells shows great promise. Further improvements
Creating complex multicellular kidney organoids from pluripotent stem cells shows great promise. Further improvements
Autor:
Christian R. Engwerda, L. Lee, Sophie Krumeich, David A. Elliott, Sean J. Humphrey, Drew M. Titmarsh, James H McMahon, Liam T Reynolds, Andreas Suhrbier, Ruraraju R, Neda R Mehdiabadi, Mark J. Smyth, David E. James, Thuy T. Le, Enzo R. Porrello, Zhao W, Tobias Bald, Ellen Mathieson, Kathy Karavendzas, Charley Mackenzie-Kludas, Kelli P. A. MacDonald, Daniel J. Rawle, Richard J. Mills, Foster, Lynn Devilee, Brendan Griffen, James E. Hudson, Partrick Rj Fortuna, Gregory A. Quaife-Ryan, Abu-Bonsrah D, Mary Lor, Kanta Subbarao, Holly K. Voges
Publikováno v:
SSRN Electronic Journal.
Cardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality. Causes are ill defined, but could be direct cardiac infection and/or ‘cytokine-storm’ induced dysfunction. To identify mechanisms and discover cardio-pr
Autor:
Drew M Titmarsh, James E Hudson, Alejandro Hidalgo, Andrew G Elefanty, Edouard G Stanley, Ernst J Wolvetang, Justin J Cooper-White
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52405 (2012)
Timed exposure of pluripotent stem cell cultures to exogenous molecules is widely used to drive differentiation towards desired cell lineages. However, screening differentiation conditions in conventional static cultures can become impractical in lar
Externí odkaz:
https://doaj.org/article/279b89e1e8bc404d85a16eed3a872ae8
Autor:
Drew M. Titmarsh, James C.H. Goh, Victor Nurcombe, Sadasivam Murali, Steve Oh, Andre J. van Wijnen, David Robinson, Jason D. Whittle, Gajadhar Bhakta, Lynn Yap, Yu Ming Lim, Robert D. Short, William R. Birch, Muriel Bardor, Lyn Chiin Sim, Allen Chen, Simon M. Cool, Andre Choo
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:1887-1896
Functionalizing medical devices with polypeptides to enhance their performance has become important for improved clinical success. The extracellular matrix (ECM) adhesion protein vitronectin (VN) is an effective coating, although the chemistry used t