Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Drew Gunio"'
Autor:
Alexandra Roudenko, Soran Mahmood, Linda Du, Drew Gunio, Irina Barash, Florence Doo, Alon Slutzky, Nina Kukar, Barak Friedman, Alexander Kagen
Publikováno v:
Tomography, Vol 7, Iss 4, Pp 573-580 (2021)
Autosomal dominant polycystic kidney disease (ADPKD) eventually leads to end stage renal disease (ESRD) with an increase in size and number of cysts over time. Progression to ESRD has previously been shown to correlate with total kidney volume (TKV).
Externí odkaz:
https://doaj.org/article/62a3bc6f0de34c38aa95ee7ce99a1152
Autor:
Askiel Bruno, Desiree D. Brooks, Taryn A. Abrams, Mitra D. Poorak, Drew Gunio, Prianka K. Kandhal, Aleena Lakhanpal, Arun K. Nagabandi, Abiodun E. Akinwuntan, Stephen Looney, Pascha E. Schafer
Publikováno v:
Clinical and Experimental Hypertension, Vol 39, Iss 6, Pp 502-504 (2017)
Background: Despite effective treatments, hypertension remains uncontrolled in nearly half of the people with hypertension in the United States. Uncontrolled hypertension leads to end organ damage, such as left ventricular hypertrophy (LVH). To ident
Externí odkaz:
https://doaj.org/article/4ca066624f38427294fcc005a57e87b7
Publikováno v:
Seminars in musculoskeletal radiology. 26(2)
Neuropathies of the elbow represent a spectrum of disorders that involve more frequently the ulnar, radial, and median nerves. Reported multiple pathogenic factors include mechanical compression, trauma, inflammatory conditions, infections, as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd396c81a6d973975f254827b602ac06
https://pubmed.ncbi.nlm.nih.gov/35609574
https://pubmed.ncbi.nlm.nih.gov/35609574
Autor:
Andrew Moreno, Sharrol Bachas, John R. Froehlig, Drew Gunio, Aaron Vanya, Teressa Alexander, Herschel Wade
Publikováno v:
Biochemistry. 55:4850-4863
Multidrug resistance (MDR) refers to the acquired ability of cells to tolerate a broad range of toxic compounds. One mechanism cells employ is to increase the level of expression of efflux pumps for the expulsion of xenobiotics. A key feature uniting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9508cd6a0412f8fee61e934c9aa53daf
https://doi.org/10.1021/acs.biochem.6b00651
https://doi.org/10.1021/acs.biochem.6b00651
Publikováno v:
Journal of Chemical Information and Modeling. 56:377-389
Solution-binding and molecular docking have been combined with a diverse collection of chemical probes to further elucidate multidrug (MD) recognition in BmrR. Whereas previous efforts have focused on structural elucidations of MD binding, the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6addcd752415939d1b02e9976bc541
https://doi.org/10.1021/acs.jcim.5b00704
https://doi.org/10.1021/acs.jcim.5b00704
Autor:
Taryn A. Abrams, Mitra D. Poorak, Askiel Bruno, Stephen W. Looney, Drew Gunio, Prianka K. Kandhal, Abiodun Emmanuel Akinwuntan, Arun Nagabandi, Desiree D. Brooks, Aleena Lakhanpal, Pascha Schafer
Publikováno v:
Clinical and experimental hypertension (New York, N.Y. : 1993). 39(6)
Despite effective treatments, hypertension remains uncontrolled in nearly half of the people with hypertension in the United States. Uncontrolled hypertension leads to end organ damage, such as left ventricular hypertrophy (LVH). To identify reasons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69cb0286e648d863710efe0a108f943
https://pubmed.ncbi.nlm.nih.gov/28722487
https://pubmed.ncbi.nlm.nih.gov/28722487
Autor:
Sankara Sethuraman, Drew Gunio, Prianka K. Kandhal, Amrinder Singh, Taryn A. Abrams, Askiel Bruno, Aleena Lakhanpal, Desiree D. Brooks, Mitra D. Poorak
Publikováno v:
Diabetesmetabolic syndrome. 11
Aims Hyperglycemia in type 2 diabetes mellitus (T2D) remains uncontrolled in approximately 50% of patients in the United States. Uncontrolled T2D is associated with various vascular complications, including stroke. We studied demographic and clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0502d8271a31f8a3a3d803dade62762
https://pubmed.ncbi.nlm.nih.gov/28705459
https://pubmed.ncbi.nlm.nih.gov/28705459
Publikováno v:
Proceedings of the National Academy of Sciences. 108:11046-11051
Current views of multidrug (MD) recognition focus on large drug-binding cavities with flexible elements. However, MD recognition in BmrR is supported by a small, rigid drug-binding pocket. Here, a detailed description of MD binding by the noncanonica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e260210ea508f0b14f5631cbf388cc
https://doi.org/10.1073/pnas.1104850108
https://doi.org/10.1073/pnas.1104850108