Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Drew Everhart"'
Autor:
Ji-jing Pang, Wen-Tao Deng, Xufeng Dai, Bo Lei, Drew Everhart, Yumiko Umino, Jie Li, Keqing Zhang, Song Mao, Sanford L. Boye, Li Liu, Vince A. Chiodo, Xuan Liu, Wei Shi, Ye Tao, Bo Chang, William W. Hauswirth
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/dc2dd842f0f744fbb9fe98631e870674
Autor:
Ji-jing Pang, Wen-Tao Deng, Xufeng Dai, Bo Lei, Drew Everhart, Yumiko Umino, Jie Li, Keqing Zhang, Song Mao, Sanford L Boye, Li Liu, Vince A Chiodo, Xuan Liu, Wei Shi, Ye Tao, Bo Chang, William W Hauswirth
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35250 (2012)
Achromatopsia is a rare autosomal recessive disorder which shows color blindness, severely impaired visual acuity, and extreme sensitivity to bright light. Mutations in the alpha subunits of the cone cyclic nucleotide-gated channels (CNGA3) are respo
Externí odkaz:
https://doaj.org/article/652baf12f6c64bd4844fc98e057c2f3a
Autor:
Shannon E Boye, Sanford L Boye, Jijing Pang, Renee Ryals, Drew Everhart, Yumiko Umino, Andy W Neeley, Joseph Besharse, Robert Barlow, William W Hauswirth
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11306 (2010)
Recessive mutations in guanylate cyclase-1 (Gucy2d) are associated with severe, early onset Leber congenital amaurosis-1(LCA1). Gucy2d encodes guanylate cyclase (GC1) is expressed in photoreceptor outer segment membranes and produces cGMP in these ce
Externí odkaz:
https://doaj.org/article/ec4e56f9bd21456a85b586deb60ca7eb
Autor:
William W. Hauswirth, Li Liu, Yumiko Umino, Bo Chang, Xufeng Dai, Drew Everhart, Robert B. Barlow, Shannon E. Boye, Ilaria Barone, Bo Lei, Sanford L. Boye, Astra Dinculescu, Enrica Strettoi, Jijing Pang, Song Mao
Publikováno v:
Molecular Therapy. 19(2):234-242
The retinal degeneration 10 (rd10) mouse is a well-characterized model of autosomal recessive retinitis pigmentosa (RP), which carries a spontaneous mutation in the β subunit of rod cGMP-phosphodiesterase (PDEβ). Rd10 mouse exhibits photoreceptor d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581cf397ef66c1076ab663e65fb46920
Publikováno v:
The Journal of Neuroscience. 27:12707-12720
Whereas the mammalian retina possesses a repertoire of factors known to establish general retinal cell types, these factors alone cannot explain the vast diversity of neuronal subtypes. In other CNS regions, the differentiation of diverse neuronal po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9408c58a2fdec5163cc03405c5434112
https://doi.org/10.1523/jneurosci.3951-07.2007
https://doi.org/10.1523/jneurosci.3951-07.2007
Autor:
E. T. Brown, Barry E. Knox, Mohammad Haeri, J. C. Pan, Lingguang Cui, Yumiko Umino, Drew Everhart, T. H. Nguyen, A. S. Glenn, B. A. Frio, Eduardo Solessio, Robert B. Barlow, Maureen J. Charron, Gustav A. Engbretson, K. Cusato, R. Hafler
Publikováno v:
Proceedings of the National Academy of Sciences. 103:19541-19545
The retina is among the most metabolically active tissues in the body, requiring a constant supply of blood glucose to sustain function. We assessed the impact of low blood glucose on the vision of C57BL/6J mice rendered hypoglycemic by a null mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0a01c278ccae4952d6b4f1e349d538
https://doi.org/10.1073/pnas.0604478104
https://doi.org/10.1073/pnas.0604478104
Autor:
Seok Hong Min, Yumiko Umino, Drew Everhart, Jijing Pang, William W. Hauswirth, Robert B. Barlow, Qiuhong Li, Adrian M. Timmers, Bo Chang, Norman L. Hawes, John J. Alexander
Publikováno v:
Nature Medicine. 13:685-687
Loss of cone function in the central retina is a pivotal event in the development of severe vision impairment for many prevalent blinding diseases. Complete achromatopsia is a genetic defect resulting in cone vision loss in 1 in 30,000 individuals. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f9ec3bc73bf799857d8f8e340c8958
https://doi.org/10.1038/nm1596
https://doi.org/10.1038/nm1596
Autor:
Vince A. Chiodo, Xufeng Dai, Drew Everhart, Jijing Pang, Yumiko Umino, Xuan Liu, Song Mao, Bo Lei, Keqing Zhang, Sanford L. Boye, Ye Tao, William W. Hauswirth, Jie Li, Bo Chang, Wei Shi, Li Liu, Wen-Tao Deng
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e35250 (2012)
PLoS ONE, Vol 7, Iss 4, p e35250 (2012)
Achromatopsia is a rare autosomal recessive disorder which shows color blindness, severely impaired visual acuity, and extreme sensitivity to bright light. Mutations in the alpha subunits of the cone cyclic nucleotide-gated channels (CNGA3) are respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e173d01425b1773fcfb7182afa818025
http://europepmc.org/articles/PMC3324465
http://europepmc.org/articles/PMC3324465
Autor:
Jijing Pang, William W. Hauswirth, Yumiko Umino, Drew Everhart, Andy W. Neeley, Robert B. Barlow, Renee C. Ryals, Sanford L. Boye, Joseph C. Besharse, Shannon E. Boye
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11306 (2010)
PLoS ONE, Vol 5, Iss 6, p e11306 (2010)
Background Recessive mutations in guanylate cyclase-1 (Gucy2d) are associated with severe, early onset Leber congenital amaurosis-1(LCA1). Gucy2d encodes guanylate cyclase (GC1) is expressed in photoreceptor outer segment membranes and produces cGMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209149998311671e3e2509a4ca9b0233
https://pubmed.ncbi.nlm.nih.gov/20593011
https://pubmed.ncbi.nlm.nih.gov/20593011
Publikováno v:
Advances in experimental medicine and biology. 613
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce4b55f414b30bb48d63d0d2603252e1
https://pubmed.ncbi.nlm.nih.gov/18188940
https://pubmed.ncbi.nlm.nih.gov/18188940