Výsledky vyhledávání - "Drew Dorshorst"

A validated surrogate analyte LC–MS/MS assay for quantitation of endogenous kynurenine and tryptophan in human plasma

Autor: Sami Mahrus, Dennis Milanowski, Kari M. Morrissey, Dennis L. Miller, Brian Dean, Stephanie Cape, Drew Dorshorst, Xiaorong Liang, Janine McKnight, Lei Tan

Publikováno v: Bioanalysis. 10:1307-1317

Aim: Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) catalyze the initial and rate-controlling step of tryptophan metabolism through the kynurenine pathway, which plays an important role in mediating immune response. Accurate m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb70afddc195e996282f3765d744585
https://doi.org/10.4155/bio-2018-0044

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Development of a multi-matrix LC–MS/MS method for urea quantitation and its application in human respiratory disease studies

Autor: Tracy Staton, Meire Bremer, Stephanie Cape, Yang Gao, Dennis Milanowski, Xiao Ding, Fang Cai, Jianshuang Wang, Brian Dean, Drew Dorshorst

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 133:96-104

In human respiratory disease studies, liquid samples such as nasal secretion (NS), lung epithelial lining fluid (ELF), or upper airway mucosal lining fluid (MLF) are frequently collected, but their volumes often remain unknown. The lack of volume inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b475ad4b909910335a40e5cf97bdec3
https://doi.org/10.1016/j.jpba.2016.11.001

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Validation and determination of taselisib, a β-sparing phosphoinositide 3-kinase (PI3K) inhibitor, in human plasma by LC–MS/MS

Autor: K. Faber, Joseph A. Ware, Janine McKnight, Drew Dorshorst, Xiao Ding, Y. Shi, Brian Dean

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 126:117-123

A liquid chromatographic-tandem mass spectrometry (LC-MS/MS) method for the determination of taselisib (GDC-0032, RO5537381) concentrations in human plasma has been developed and validated to support bioanalysis of clinical samples. Solid phase extra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15af23c5ab7bc1d9ef5632619ffdc697
https://doi.org/10.1016/j.jpba.2016.04.030

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Corrigendum to 'Simultaneous determination of itraconazole, hydroxy itraconazole, keto itraconazole and N-desalkyl itraconazole concentration in human plasma using liquid chromatography with tandem mass spectrometry' [J. Chromatogr. B 1020 (2016) 111–119]

Autor: Jialin Mao, Michael Van Parys, Yuzhong Deng, Xiao Ding, Janine McKnight, Drew Dorshorst, Brian Dean, Joseph A. Ware, Cornelis E. C. A. Hop, Luke Bi, Yuan Chen, Ning Zeng, Dennis Milanowski, Xiaorong Liang

Publikováno v: Journal of Chromatography B. :239

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f336171342a8f37bf36b796dea144f
https://doi.org/10.1016/j.jchromb.2016.06.023

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