Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Drew C. Deniger"'
Autor:
Gal Cafri, Rami Yossef, Anna Pasetto, Drew C. Deniger, Yong-Chen Lu, Maria Parkhurst, Jared J. Gartner, Li Jia, Satyajit Ray, Lien T. Ngo, Mohammad Jafferji, Abraham Sachs, Todd Prickett, Paul F. Robbins, Steven A. Rosenberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Adoptive cell therapy (ACT) using neoantigen-specific T cells can lead to tumor regression. Here the authors use an in vitro stimulation approach to isolate tumor specific memory T cells from peripheral blood of metastatic epithelial cancer patients
Externí odkaz:
https://doaj.org/article/4abe5b00b67f409c95fdd11f690fc2b9
Autor:
Sanghyun P. Kim, Nolan R. Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J. Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C. Deniger, Frank J. Lowery, Maria R. Parkhurst, Lien T. Ngo, Satyajit Ray, Yong F. Li, Victoria Hill, Maria Florentin, Robert V. Masi, Biman C. Paria, Noam Levin, Alakesh Bera, Elizabeth A. Hedges, Agnes Choi, Praveen D. Chatani, Anup Y. Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D. Prickett, Li Jia, Jonathan M. Hernandez, Chuong D. Hoang, Paul F. Robbins, Stephanie L. Goff, Richard M. Sherry, James C. Yang, Steven A. Rosenberg
Publikováno v:
Cancer Immunology Research. 10:932-946
Adoptive cellular therapy (ACT) targeting neoantigens can achieve durable clinical responses in patients with cancer. Most neoantigens arise from patient-specific mutations, requiring highly individualized treatments. To broaden the applicability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd7c2cf7704a11e5d74fd00ce2ec8d0
https://doi.org/10.1158/2326-6066.cir-22-0040
https://doi.org/10.1158/2326-6066.cir-22-0040
Autor:
Steven A. Rosenberg, James C. Yang, Richard M. Sherry, Stephanie L. Goff, Paul F. Robbins, Chuong D. Hoang, Jonathan M. Hernandez, Li Jia, Todd D. Prickett, Zhili Zheng, Yong-Chen Lu, Samantha Seitter, Shoshana Levi, Anup Y. Parikh, Praveen D. Chatani, Agnes Choi, Elizabeth A. Hedges, Alakesh Bera, Noam Levin, Biman C. Paria, Robert V. Masi, Maria Florentin, Victoria Hill, Yong F. Li, Satyajit Ray, Lien T. Ngo, Maria R. Parkhurst, Frank J. Lowery, Drew C. Deniger, Parisa Malekzadeh, Sivasish Sindiri, Jared J. Gartner, Billel Gasmi, Zhiya Yu, Sri Krishna, Nikolaos Zacharakis, Nolan R. Vale, Sanghyun P. Kim
Supplementary Figure from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e3f8c006b4d5783eb104fc14a96821
https://doi.org/10.1158/2326-6066.22545620.v1
https://doi.org/10.1158/2326-6066.22545620.v1
Autor:
Steven A. Rosenberg, James C. Yang, Richard M. Sherry, Stephanie L. Goff, Paul F. Robbins, Chuong D. Hoang, Jonathan M. Hernandez, Li Jia, Todd D. Prickett, Zhili Zheng, Yong-Chen Lu, Samantha Seitter, Shoshana Levi, Anup Y. Parikh, Praveen D. Chatani, Agnes Choi, Elizabeth A. Hedges, Alakesh Bera, Noam Levin, Biman C. Paria, Robert V. Masi, Maria Florentin, Victoria Hill, Yong F. Li, Satyajit Ray, Lien T. Ngo, Maria R. Parkhurst, Frank J. Lowery, Drew C. Deniger, Parisa Malekzadeh, Sivasish Sindiri, Jared J. Gartner, Billel Gasmi, Zhiya Yu, Sri Krishna, Nikolaos Zacharakis, Nolan R. Vale, Sanghyun P. Kim
Adoptive cellular therapy (ACT) targeting neoantigens can achieve durable clinical responses in patients with cancer. Most neoantigens arise from patient-specific mutations, requiring highly individualized treatments. To broaden the applicability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c6a0f591f57b24fb7e630d112f7f94
https://doi.org/10.1158/2326-6066.c.6550985.v1
https://doi.org/10.1158/2326-6066.c.6550985.v1
Autor:
Steven A. Rosenberg, Robert P.T. Somerville, John R. Wunderlich, Mojgan Ahmadzadeh, Parisa Malekzadeh, Drew C. Deniger, Gal Cafri, Winifred Lo, Stephanie L. Goff, Frank J. Lowery, Rami Yossef, Anna Pasetto, Scott Kivitz, Lien T. Ngo, Satyajit Ray, Eric Groh, Abraham Sachs, Jessica S. Crystal, Almin Lalani, Mona El-Gamil, Yong F. Li, Gabriel Ivey, Li Jia, Jared J. Gartner, Todd D. Prickett, Eric Tran, Paul F. Robbins, Maria R. Parkhurst
Immunotherapies can mediate regression of human tumors with high mutation rates, but responses are rarely observed in patients with common epithelial cancers. This raises the question of whether patients with these common cancers harbor T lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a2a4ddb459878d5287a4a96915ed83c
https://doi.org/10.1158/2159-8290.c.6547957.v1
https://doi.org/10.1158/2159-8290.c.6547957.v1
Autor:
Steven A. Rosenberg, Jessica S. Crystal, Katarzyna Trebska-McGowan, Jared Gartner, Maria R. Parkhurst, Harlan Robins, Bryan Howie, Daniel C. Douek, Rodrigo Matus-Nicodemos, Todd D. Prickett, Drew C. Deniger, Paul F. Robbins, Alena Gros, Anna Pasetto
Gating strategy, Shannon entropy, PD-1 expression, additional co-culture data, primers sequence, Frequency of the top 10 CD8+PD-1+ TCRB in bulk unsorted TIL and sorted TIL subsets, Retrospective analysis of pairing the most frequent TCRB in the CD8+P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18367889110460b48bb9bc005e4ef135
https://doi.org/10.1158/2326-6066.22537856.v1
https://doi.org/10.1158/2326-6066.22537856.v1
Autor:
Steven A. Rosenberg, Robert P.T. Somerville, John R. Wunderlich, Mojgan Ahmadzadeh, Parisa Malekzadeh, Drew C. Deniger, Gal Cafri, Winifred Lo, Stephanie L. Goff, Frank J. Lowery, Rami Yossef, Anna Pasetto, Scott Kivitz, Lien T. Ngo, Satyajit Ray, Eric Groh, Abraham Sachs, Jessica S. Crystal, Almin Lalani, Mona El-Gamil, Yong F. Li, Gabriel Ivey, Li Jia, Jared J. Gartner, Todd D. Prickett, Eric Tran, Paul F. Robbins, Maria R. Parkhurst
Supplementary Figures 1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e0fb582e053a61b07254758048727c
https://doi.org/10.1158/2159-8290.22535827.v1
https://doi.org/10.1158/2159-8290.22535827.v1
Autor:
Steven A. Rosenberg, Robert P.T. Somerville, John R. Wunderlich, Mojgan Ahmadzadeh, Parisa Malekzadeh, Drew C. Deniger, Gal Cafri, Winifred Lo, Stephanie L. Goff, Frank J. Lowery, Rami Yossef, Anna Pasetto, Scott Kivitz, Lien T. Ngo, Satyajit Ray, Eric Groh, Abraham Sachs, Jessica S. Crystal, Almin Lalani, Mona El-Gamil, Yong F. Li, Gabriel Ivey, Li Jia, Jared J. Gartner, Todd D. Prickett, Eric Tran, Paul F. Robbins, Maria R. Parkhurst
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ef3a4e59eeeb735a86058ec5edd253
https://doi.org/10.1158/2159-8290.22535836.v1
https://doi.org/10.1158/2159-8290.22535836.v1
Autor:
Steven A. Rosenberg, Jessica S. Crystal, Katarzyna Trebska-McGowan, Jared Gartner, Maria R. Parkhurst, Harlan Robins, Bryan Howie, Daniel C. Douek, Rodrigo Matus-Nicodemos, Todd D. Prickett, Drew C. Deniger, Paul F. Robbins, Alena Gros, Anna Pasetto
Adoptive transfer of T cells with engineered T-cell receptor (TCR) genes that target tumor-specific antigens can mediate cancer regression. Accumulating evidence suggests that the clinical success of many immunotherapies is mediated by T cells target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32f756e67c9f5eec0686a55a42d7f64c
https://doi.org/10.1158/2326-6066.c.6548573.v1
https://doi.org/10.1158/2326-6066.c.6548573.v1
Autor:
Steven A. Rosenberg, Robert P.T. Somerville, David N. Danforth, John R. Wunderlich, Michelle M. Langhan, Rami Yossef, Li Jia, Parisa Malekzadeh, Biman C. Paria, Todd D. Prickett, Jared J. Gartner, Paul F. Robbins, Anna Pasetto, Drew C. Deniger
Clinical details (S1) and neoepitope details (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2aed9dca2c37d05047ea434fdf87d7
https://doi.org/10.1158/1078-0432.22469351
https://doi.org/10.1158/1078-0432.22469351