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Estrogen receptor beta signaling in CD8 ⁺ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch.

Autor: Yuan B; Department of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA., Clark CA; Department of Medicine, The Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, USA., Wu B; Department of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA., Yang J; Department of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA., Drerup JM; Department of Medicine, The Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, USA., Li T; Department of Molecular Medicine, The Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, USA., Jin VX; Department of Molecular Medicine, The Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, USA., Hu Y; Department of Anatomy & Cell Biology, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA., Curiel TJ; Department of Medicine, The Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, USA rli69@gwu.edu curielt@uthscsa.edu., Li R; Department of Biochemistry & Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, District of Columbia, USA rli69@gwu.edu curielt@uthscsa.edu.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Jan; Vol. 9 (1).

Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model.

Autor: Padrón Á; Department of Medicine, University of Texas Health San Antonio, TX 78229, United States., Hurez V; Department of Medicine, University of Texas Health San Antonio, TX 78229, United States., Gupta HB; Department of Medicine, University of Texas Health San Antonio, TX 78229, United States., Clark CA; Department of Microbiology, Immunology & Molecular Genetics, University of Texas Health San Antonio, TX 78229, United States., Pandeswara SL; Department of Medicine, University of Texas Health San Antonio, TX 78229, United States., Yuan B; Department of Molecular Medicine, University of Texas Health San Antonio, TX 78229, United States., Svatek RS; Department of Urology, University of Texas Health San Antonio, TX 78229, United States; The UT Health Cancer Center, University of Texas Health San Antonio, TX 78229, United States., Turk MJ; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, United States., Drerup JM; Department of Microbiology, Immunology & Molecular Genetics, University of Texas Health San Antonio, TX 78229, United States., Li R; Department of Molecular Medicine, University of Texas Health San Antonio, TX 78229, United States; The UT Health Cancer Center, University of Texas Health San Antonio, TX 78229, United States., Curiel TJ; Department of Medicine, University of Texas Health San Antonio, TX 78229, United States; Department of Microbiology, Immunology & Molecular Genetics, University of Texas Health San Antonio, TX 78229, United States; The UT Health Cancer Center, University of Texas Health San Antonio, TX 78229, United States; The Barshop Institute for Aging and Longevity Studies, University of Texas Health, San Antonio, TX 78229, United States. Electronic address: curielt@uthscsa.edu.

Publikováno v: Experimental gerontology [Exp Gerontol] 2018 May; Vol. 105, pp. 146-154. Date of Electronic Publication: 2018 Jan 08.

Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma.

Autor: Clark CA; The Graduate School of Biomedical Sciences, University of Texas Health Science Center, San Antonio, Texas.; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Gupta HB; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Sareddy G; Cancer Therapy & Research Center, University of Texas Health Science Center, San Antonio, Texas.; Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, Texas., Pandeswara S; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Lao S; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Yuan B; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas.; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, Texas., Drerup JM; The Graduate School of Biomedical Sciences, University of Texas Health Science Center, San Antonio, Texas.; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Padron A; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Conejo-Garcia J; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania., Murthy K; The Graduate School of Biomedical Sciences, University of Texas Health Science Center, San Antonio, Texas.; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Liu Y; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas.; Xiangya School of Medicine, Central South University, Changsha, Hunan, PR China., Turk MJ; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire., Thedieck K; Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands and Department for Neuroscience, School of Medicine and Health Sciences, University Oldenburg, Oldenburg, Germany., Hurez V; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas., Li R; The Graduate School of Biomedical Sciences, University of Texas Health Science Center, San Antonio, Texas.; Cancer Therapy & Research Center, University of Texas Health Science Center, San Antonio, Texas.; Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, Texas., Vadlamudi R; The Graduate School of Biomedical Sciences, University of Texas Health Science Center, San Antonio, Texas.; Cancer Therapy & Research Center, University of Texas Health Science Center, San Antonio, Texas.; Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, Texas., Curiel TJ; The Graduate School of Biomedical Sciences, University of Texas Health Science Center, San Antonio, Texas. curielt@uthscsa.edu.; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas.; Cancer Therapy & Research Center, University of Texas Health Science Center, San Antonio, Texas.

Publikováno v: Cancer research [Cancer Res] 2016 Dec 01; Vol. 76 (23), pp. 6964-6974. Date of Electronic Publication: 2016 Sep 26.