Continuous manufacturing of pharmaceutical products: A density-insensitive near infrared method for the in-line monitoring of continuous powder streams.

Autor: Velez-Silva NL; Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, PA 15282, United States; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA 15282, United States., Drennen JK 3rd; Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, PA 15282, United States; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA 15282, United States., Anderson CA; Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, PA 15282, United States; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA 15282, United States. Electronic address: andersonca@duq.edu.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2024 Jan 25; Vol. 650, pp. 123699. Date of Electronic Publication: 2023 Dec 10.

NIR Spectroscopy as an Online PAT Tool for a Narrow Therapeutic Index Drug: Toward a Platform Approach Across Lab and Pilot Scales for Development of a Powder Blending Monitoring Method and Endpoint Determination.

Autor: Talwar S; Duquesne University Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA, 15282, USA.; MST-BPDS-Biopharm Product Dev & Supply, GSK, 709 Swedeland Road, King of Prussia, PA, 19406, USA., Pawar P; Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ, 08854, USA.; Gilead, Foster City, CA, 94404, USA., Wu H; Office of Pharmaceutical Quality, CDER, FDA, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA. Huiquan.wu@fda.hhs.gov., Sowrirajan K; Office of Pharmaceutical Quality, CDER, FDA, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA., Wu S; Office of Pharmaceutical Quality, CDER, FDA, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA., Igne B; Duquesne University Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA, 15282, USA., Friedman R; Office of Manufacturing Quality, Office of Compliance, CDER, FDA, Silver Spring, MD, 20993, USA., Muzzio FJ; Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ, 08854, USA., Drennen JK 3rd; Duquesne University Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA, 15282, USA. Drennen@duq.edu.

Publikováno v: The AAPS journal [AAPS J] 2022 Sep 28; Vol. 24 (6), pp. 103. Date of Electronic Publication: 2022 Sep 28.

Terahertz Time of Flight Spectroscopy as a Coating Thickness Reference Method for Partial Least Squares Near Infrared Spectroscopy Models.

Autor: Mohan S; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, United States.; Duquesne University, Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282, United States., Odani N; Manufacturing Technology Department, Towa Pharmaceutical Co., Ltd., Ichiban-cho, Kadoma, Osaka 571-0033, Japan., Hossain MN; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, United States.; Duquesne University, Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282, United States., Feng H; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, United States.; Duquesne University, Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282, United States., Li Y; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, United States.; Duquesne University, Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282, United States., Kato E; New Concept Product Initiative, Advantest Corporation, Sendai 989-3124 Japan., Drennen JK 3rd; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, United States.; Duquesne University, Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282, United States., Anderson CA; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, United States.; Duquesne University, Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2020 Mar 03; Vol. 92 (5), pp. 3658-3665. Date of Electronic Publication: 2020 Feb 20.

Refractive Index Measurement of Pharmaceutical Solids: A Review of Measurement Methods and Pharmaceutical Applications.

Autor: Mohan S; Division of Pharmaceutical, Social and Administrative Sciences, Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282; Division of Pharmaceutical, Social and Administrative Sciences, Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282., Kato E; New Concept Product Initiative, Advantest Corporation, Sendai 989-3124, Japan., Drennen JK 3rd; Division of Pharmaceutical, Social and Administrative Sciences, Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282; Division of Pharmaceutical, Social and Administrative Sciences, Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282., Anderson CA; Division of Pharmaceutical, Social and Administrative Sciences, Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282; Division of Pharmaceutical, Social and Administrative Sciences, Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282. Electronic address: andersonca@duq.edu.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2019 Nov; Vol. 108 (11), pp. 3478-3495. Date of Electronic Publication: 2019 Jul 17.

Prediction of Dissolution Profiles From Process Parameters, Formulation, and Spectroscopic Measurements.

Autor: Zhao Y; Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282., Li W; Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282., Shi Z; SMDD, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285., Drennen JK 3rd; Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282., Anderson CA; Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282. Electronic address: andersonca@duq.edu.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2019 Jun; Vol. 108 (6), pp. 2119-2127. Date of Electronic Publication: 2019 Feb 08.