Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells.

Autor: Le Moine M; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium., Azouz A; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium., Sanchez Sanchez G; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium; Department of Pharmacotherapy and Pharmaceutics, ULB, Brussels, Belgium., Dejolier S; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium; Immunobiology Lab, ULB, Gosselies, Belgium., Nguyen M; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium., Thomas S; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium., Shala V; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium., Dreidi H; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium; Immunobiology Lab, ULB, Gosselies, Belgium., Denanglaire S; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium; Immunobiology Lab, ULB, Gosselies, Belgium., Libert F; Institute of Interdisciplinary Research (IRIBHM) and Brightcore, ULB, Brussels, Belgium., Vermijlen D; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium; Department of Pharmacotherapy and Pharmaceutics, ULB, Brussels, Belgium; WELBIO Department, WEL Research Institute, Avenue Pasteur, 6, 1300 Wavre, Belgium., Andris F; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium; Immunobiology Lab, ULB, Gosselies, Belgium., Goriely S; Institute for Medical Immunology (IMI), Université Libre de Bruxelles (ULB), Gosselies, Belgium; ULB Center for Research in Immunology (U-CRI), ULB, Brussels, Belgium; Immunobiology Lab, ULB, Gosselies, Belgium. Electronic address: stanislas.goriely@ulb.be.

Publikováno v: Cell reports [Cell Rep] 2023 Aug 29; Vol. 42 (8), pp. 112876. Date of Electronic Publication: 2023 Aug 04.