Zobrazeno 1 - 5
of 5
pro vyhledávání: '"DreeAnna Morris"'
Adenosine A2A Receptor Activation Enhances Blood–Tumor Barrier Permeability in a Rodent Glioma Model
Autor:
Jessica Bills, Meili Zhang, Dionne Davis, Monica Manglani, Kunio Nagashima, Stuart Walbridge, Brandon Foster, Dorian B. McGavern, Priya Shankarappa, Amélie Vézina, DreeAnna Morris, Matthew McCord, Hua Song, Jessica Kindrick, William D. Figg, Wei Zhang, Leslie L. Muldoon, Sadhana Jackson, Mark R. Gilbert, Cody J. Peer
Publikováno v:
Mol Cancer Res
The blood–tumor barrier (BTB) limits the entry of effective chemotherapeutic agents into the brain for treatment of malignant tumors like glioblastoma. Poor drug entry across the BTB allows infiltrative glioma stem cells to evade therapy and develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f94ac14946ad5afcef38a0ddff53d7
https://doi.org/10.1158/1541-7786.mcr-19-0995
https://doi.org/10.1158/1541-7786.mcr-19-0995
Publikováno v:
Neuro Oncol
BACKGROUND Breast cancer brain metastases have poor prognosis and few treatment options. When breast cancer cells invade the brain they interact with the vasculature and resident brain cells including microglia and astrocytes. We hypothesize that bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfd2f31463284c38788e1c5572ef986
https://europepmc.org/articles/PMC6846158/
https://europepmc.org/articles/PMC6846158/
Publikováno v:
Cancer Immunology Research. 8:A89-A89
Background: Breast cancer brain metastases have poor prognosis and few treatment options. When breast cancer cells invade the brain, they interact with the vasculature and resident brain cells, including microglia and astrocytes. We hypothesize that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d909fb791f1a6fd8d5a945fdcd913b95
https://doi.org/10.1158/2326-6074.tumimm19-a89
https://doi.org/10.1158/2326-6074.tumimm19-a89
Autor:
Prakash Ambady, Michael A. Pagel, DreeAnna Morris, Leslie L. Muldoon, Cymon Kersch, Edward A. Neuwelt, Jeffrey Wu
Publikováno v:
Cancer Research. 77:5087-5087
Background: This study evaluates the use of a sub-lethal dose of ionizing radiation to guide and enhance the intracellular delivery of morpholino antisense nucleotides designed to block O6-methylguanine DNA methyltransferase (MGMT) to enhance the cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f59d7ce0221d735510f29224cf5facf
https://doi.org/10.1158/1538-7445.am2017-5087
https://doi.org/10.1158/1538-7445.am2017-5087
Autor:
Edward A. Neuwelt, Leslie L. Muldoon, Joshua M. Walker, Jeffrey Wu, DreeAnna Morris, Michael A. Pagel, Prakash Ambady, Randy Woltjer
Publikováno v:
Molecular Cancer Research. 15:B38-B38
High levels of DNA repair enzyme O6-methylguanine DNA methyltransferase (MGMT) in glioblastoma tumor are associated with temozolomide resistance and poor prognosis. MGMT provides a promising therapeutic target to overcome chemo-resistance and improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::866670b435b2d9ce9589f405449e4a49
https://doi.org/10.1158/1557-3125.dnarepair16-b38
https://doi.org/10.1158/1557-3125.dnarepair16-b38