Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Drashya Sharma"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Sepsis is a major health problem in the United States (US), constituting a leading contributor to mortality among critically ill patients. Despite advances in treatment the underlying pathophysiology of sepsis remains elusive. Reactive oxygen species
Externí odkaz:
https://doaj.org/article/3f8597b2ca624ab384f90cef44035166
Publikováno v:
International Journal of Peptide Research and Therapeutics
Multidrug resistant Shigella is one of the leading causes of mortality in children and infants. Availability of vaccine could prevent the Shigella infection and reduce the mortality. Conventional approaches of vaccine development against shigellosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f6d7c5eb1b981bdeda24af3b895217
https://doi.org/10.1007/s10989-020-10153-0
https://doi.org/10.1007/s10989-020-10153-0
Autor:
Drashya Sharma, J. David Farrar
Publikováno v:
Seminars in Immunopathology
The sympathetic nervous system integrates the functions of multiple organ systems by regulating their autonomic physiological activities. The immune system is regulated both locally and systemically by the neurotransmitters epinephrine and norepineph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3627c89efad2d363e1fb37006ea928
https://doi.org/10.1007/s00281-020-00829-6
https://doi.org/10.1007/s00281-020-00829-6
Publikováno v:
Vaccine
Highlights • LacVax® OmpA elicited humoral and cellular immune responses in BALB/c mice. • Oral immunization with LacVax® OmpA elicited sIgA, a hallmark of mucosal immunity. • LacVax® OmpA immunized mice were protected against Shigella induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbd8086af4bd46707a035235b07abb9
https://doi.org/10.1016/j.vaccine.2019.04.053
https://doi.org/10.1016/j.vaccine.2019.04.053
Publikováno v:
Gene Therapy. 25:485-496
The non-invasive food grade Lactococcus lactis (L. lactis) represents a safe and attractive alternative to invasive pathogens for the delivery of plasmid DNA at mucosal sites. We have earlier shown the DNA delivery potential of r-L. lactis harboring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1c876f8e95fb79ab16d74e145c002f2
https://doi.org/10.1038/s41434-018-0033-8
https://doi.org/10.1038/s41434-018-0033-8
Publikováno v:
Microbiology and Immunology. 61:123-129
Food grade Lactococcus lactis has been widely used as an antigen and DNA delivery vehicle. We have previously reported the use of non-invasive L. lactis to deliver the newly constructed immunostimulatory DNA vaccine reporter plasmid, pPERDBY. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7cf847a03c59628b448dba6b5c4c4f
https://doi.org/10.1111/1348-0421.12473
https://doi.org/10.1111/1348-0421.12473
Publikováno v:
Microbes and Infection. 19:47-54
Shigellosis, a major cause of mortality and morbidity, requires development of effective intervention strategy for which animal model mimicking human pathology is essential. Among various animal models for shigellosis, mice being more convenient have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ccb4110dbed80ac4667412ba12b176
https://doi.org/10.1016/j.micinf.2016.09.002
https://doi.org/10.1016/j.micinf.2016.09.002
Publikováno v:
International Journal of Peptide Research and Therapeutics. 22:481-495
Diarrhoeal diseases due to Shigellosis account for deaths of ~1.5 million children every year in developing countries. Outer membrane proteins (OMPs) of Gram negative bacteria have been shown to be excellent subunit vaccine candidates against various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c69beb7c418eb12361ed516abf890f1
https://doi.org/10.1007/s10989-016-9528-6
https://doi.org/10.1007/s10989-016-9528-6
Publikováno v:
Gene therapy. 25(7)
The non-invasive food grade Lactococcus lactis (L. lactis) represents a safe and attractive alternative to invasive pathogens for the delivery of plasmid DNA at mucosal sites. We have earlier shown the DNA delivery potential of r-L. lactis harboring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9881f751ff587750adb679682ebc10ee
https://pubmed.ncbi.nlm.nih.gov/30108273
https://pubmed.ncbi.nlm.nih.gov/30108273
Publikováno v:
Indian Journal of Pharmaceutical Sciences. 79
The extensive demand of large scale therapeutic protein production in Chinese Hamster Ovarian cell lines increased the need of developing efficient and cost effective transfection reagent. Polyethylenimine has recently emerged as an attractive altern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48da0cf05017261af399d80e1661e696
https://doi.org/10.4172/pharmaceutical-sciences.1000276
https://doi.org/10.4172/pharmaceutical-sciences.1000276