Differential protein-protein interactions underlie signaling mediated by the TCR and a 4-1BB domain-containing CAR.

Autor: Ritmeester-Loy SA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Draper IH; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Bueter EC; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Lautz JD; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Zhang-Wong Y; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Gustafson JA; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, WA 98101, USA., Wilson AL; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, WA 98101, USA., Lin C; Proteomics and Metabolomics Facility, Fred Hutchinson Cancer Center, Seattle, WA 98101, USA., Gafken PR; Proteomics and Metabolomics Facility, Fred Hutchinson Cancer Center, Seattle, WA 98101, USA., Jensen MC; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA., Orentas R; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA 98101, USA.

Publikováno v: Science signaling [Sci Signal] 2024 Mar 05; Vol. 17 (826), pp. eadd4671. Date of Electronic Publication: 2024 Mar 05.