Medication improves velocity, reaction time, and movement time but not amplitude or error during memory-guided reaching in Parkinson's disease.

Autor: Trevarrow MP; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, USA., Munoz MJ; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, USA., Rivera YM; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, USA., Arora R; Morsani College of Medicine, University of South Florida, Tampa, Florida, USA., Drane QH; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, USA., Pal GD; Division of Movement Disorders, Department of Neurology, Rutgers - Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA., Verhagen Metman L; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Goelz LC; Department of Kinesiology and Nutrition, UIC College of Applied Health Sciences, Chicago, Illinois, USA., Corcos DM; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, USA.; McCormick School of Engineering, Northwestern University, Evanston, Illinois, USA., David FJ; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, USA.

Publikováno v: Physiological reports [Physiol Rep] 2024 Sep; Vol. 12 (17), pp. e16150.

Medication only improves limb movements while deep brain stimulation improves eye and limb movements during visually-guided reaching in Parkinson's disease.

Autor: Munoz MJ; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States., Arora R; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.; USF Health Morsani College of Medicine, University of South Florida, Tampa, FL, United States., Rivera YM; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States., Drane QH; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States., Pal GD; Department of Neurology, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, United States.; Department of Neurological Sciences, Section of Parkinson Disease and Movement Disorders, Rush University Medical Center, Chicago, IL, United States., Verhagen Metman L; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Sani SB; Department of Neurosurgery, Rush University Medical Center, Chicago, IL, United States., Rosenow JM; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Goelz LC; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, United States., Corcos DM; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States., David FJ; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.

Publikováno v: Frontiers in human neuroscience [Front Hum Neurosci] 2023 Oct 02; Vol. 17, pp. 1224611. Date of Electronic Publication: 2023 Oct 02 (Print Publication: 2023).

Medication adversely impacts visually-guided eye movements in Parkinson's disease.

Autor: Munoz MJ; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA. Electronic address: mirandamunoz2022@u.northwestern.edu., Reilly JL; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Pal GD; Department of Neurology, Rutgers University, New Brunswick, NJ, USA; Department of Neurological Sciences, Section of Parkinson Disease and Movement Disorders, Rush University Medical Center, Chicago, IL, USA., Verhagen Metman L; Department of Neurological Sciences, Section of Parkinson Disease and Movement Disorders, Rush University Medical Center, Chicago, IL, USA., Rivera YM; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA., Drane QH; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA., Corcos DM; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA., David FJ; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA., Goelz LC; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.

Publikováno v: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2022 Nov; Vol. 143, pp. 145-153. Date of Electronic Publication: 2022 Aug 08.

A Genetic Toggle for Chemical Control of Individual Plk1 Substrates.

Autor: Johnson JM; Department of Medicine, Division of Hematology/Oncology, University of Wisconsin, 1111 Highland Avenue, WIMR 6059, Madison, WI 53705, USA; University of Wisconsin Carbone Cancer Center, University of Wisconsin, Madison, WI 53705, USA., Hebert AS; Genome Center, University of Wisconsin, Madison, WI 53705, USA; Morgridge Institute for Research, Madison, WI 53705, USA., Drane QH; Department of Medicine, Division of Hematology/Oncology, University of Wisconsin, 1111 Highland Avenue, WIMR 6059, Madison, WI 53705, USA; University of Wisconsin Carbone Cancer Center, University of Wisconsin, Madison, WI 53705, USA., Lera RF; Department of Medicine, Division of Hematology/Oncology, University of Wisconsin, 1111 Highland Avenue, WIMR 6059, Madison, WI 53705, USA; University of Wisconsin Carbone Cancer Center, University of Wisconsin, Madison, WI 53705, USA., Wan J; Physiology Training Program, University of Wisconsin, Madison, WI 53705, USA., Weaver BA; University of Wisconsin Carbone Cancer Center, University of Wisconsin, Madison, WI 53705, USA; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI 53705, USA; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI 53705, USA., Coon JJ; Genome Center, University of Wisconsin, Madison, WI 53705, USA; Department of Chemistry, University of Wisconsin, Madison, WI 53705, USA; Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53705, USA; Morgridge Institute for Research, Madison, WI 53705, USA., Burkard ME; Department of Medicine, Division of Hematology/Oncology, University of Wisconsin, 1111 Highland Avenue, WIMR 6059, Madison, WI 53705, USA; University of Wisconsin Carbone Cancer Center, University of Wisconsin, Madison, WI 53705, USA; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI 53705, USA. Electronic address: mburkard@wisc.edu.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2020 Mar 19; Vol. 27 (3), pp. 350-362.e8. Date of Electronic Publication: 2020 Feb 03.