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Akademický článek

In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.

Autor: Dranchak PK; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Oliphant E; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Queme B; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Lamy L; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Wang Y; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Huang R; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Xia M; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Tao D; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Inglese J; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.; Metabolic Medicine Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20817, USA.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2023 Mar 01; Vol. 16 (3). Date of Electronic Publication: 2023 Mar 20.

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Akademický článek

Serum-Stable and Selective Backbone-N-Methylated Cyclic Peptides That Inhibit Prokaryotic Glycolytic Mutases.

Autor: van Neer RHP; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan., Dranchak PK; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Liu L; Protein Structure and X-ray Crystallography Laboratory, Structural Biology Center, University of Kansas, Lawrence, Kansas 66045, United States., Aitha M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Queme B; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Kimura H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan., Katoh T; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan., Battaile KP; New York Structural Biology Center, NSLS-II, Upton, New York 11973, United States., Lovell S; Protein Structure and X-ray Crystallography Laboratory, Structural Biology Center, University of Kansas, Lawrence, Kansas 66045, United States., Inglese J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, United States., Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2022 Aug 19; Vol. 17 (8), pp. 2284-2295. Date of Electronic Publication: 2022 Jul 29.

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Akademický článek

Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for PMP22 Gene-Dosage Disorder Drug Discovery.

Autor: Martinez NJ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Braisted JC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Dranchak PK; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Moran JJ; Department of Comparative Biosciences, and Waisman Center, University of Wisconsin, Madison, Wisconsin 53705, United States., Larson H; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Queme B; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Pak E; National Human Genome Research Institute, National Institute of Health, Bethesda, Maryland 20817, United States., Dutra A; National Human Genome Research Institute, National Institute of Health, Bethesda, Maryland 20817, United States., Rai G; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Cheng KC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Svaren J; Department of Comparative Biosciences, and Waisman Center, University of Wisconsin, Madison, Wisconsin 53705, United States., Inglese J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.; National Human Genome Research Institute, National Institute of Health, Bethesda, Maryland 20817, United States.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2021 Jun 10; Vol. 4 (4), pp. 1422-1436. Date of Electronic Publication: 2021 Jun 10 (Print Publication: 2021).

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Akademický článek

Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.

Autor: Wiedmann M; Department of Chemistry, Graduate School of Sciences, The University of Tokyo, Tokyo, Japan., Dranchak PK; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Aitha M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Queme B; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Collmus CD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Kashipathy MM; Protein Structure Laboratory, Structural Biology Center, University of Kansas, Lawrence, Kansas, USA., Kanter L; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Lamy L; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Rogers JM; Department of Chemistry, Graduate School of Sciences, The University of Tokyo, Tokyo, Japan., Tao D; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Battaile KP; IMCA-CAT Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois, USA., Rai G; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA., Lovell S; Protein Structure Laboratory, Structural Biology Center, University of Kansas, Lawrence, Kansas, USA., Suga H; Department of Chemistry, Graduate School of Sciences, The University of Tokyo, Tokyo, Japan. Electronic address: hsuga@chem.s.u-tokyo.ac.jp., Inglese J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: jinglese@mail.nih.gov.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100628. Date of Electronic Publication: 2021 Apr 01.

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Akademický článek

High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.

Autor: Kinder TB; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20852, United States., Dranchak PK; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20852, United States., Inglese J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20852, United States.; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20814, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2020 Jul 17; Vol. 15 (7), pp. 1974-1986. Date of Electronic Publication: 2020 Jun 10.

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Akademický článek

A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.

Autor: Getz RA; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA., Kwak G; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA., Cornell S; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA., Mbugua S; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA. Electronic address: mbugua@bc.edu., Eberhard J; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA. Electronic address: eberharj@bc.edu., Huang SX; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA. Electronic address: huangsi@bc.edu., Abbasi Z; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA. Electronic address: abbasiz@bc.edu., de Medeiros AS; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA., Thomas R; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA. Electronic address: thomasry@bc.edu., Bukowski B; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA. Electronic address: bukowskb@bc.edu., Dranchak PK; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA. Electronic address: patricia.dranchak@nih.gov., Inglese J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA. Electronic address: jinglese@mail.nih.gov., Hoffman CS; Biology Department, Boston College, 140 Commonwealth Ave., Chestnut Hill, MA 02467, USA. Electronic address: hoffmacs@bc.edu.

Publikováno v: Cellular signalling [Cell Signal] 2019 Aug; Vol. 60, pp. 114-121. Date of Electronic Publication: 2019 Apr 24.

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