Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dramane Ibrahim Laine"'
Autor:
Lisa Burns, Ruoqi Peng, Carla M. T. Bauer, Lorena Renteria, Paul Harris, Christopher S. Stevenson, Dramane Ibrahim Laine, Jonathan E. Phillips
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 29:233-241
In allergen-induced asthma, activated mast cells start the lung inflammatory process with degranulation, cytokine synthesis, and mediator release. Bruton's tyrosine kinase (Btk) activity is required for the mast cell activation during IgE-mediated se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598adc53220071720df0ca8a24827e79
https://doi.org/10.1089/jamp.2015.1210
https://doi.org/10.1089/jamp.2015.1210
Autor:
Yonglin Ren, Ryan Craig Schoenfeld, Adrian J. Fretland, Maria E. Fuentes, Kung-Ching Chang, Yimin Qian, Rachid Hamid, Yun Chen, Achyutharao Sidduri, Matthew Michael Hamilton, Christopher S. Stevenson, Gabriel Stephen Deems, Lin Zhang, Terry Truitt, Dramane Ibrahim Laine, Arjun Narayanan, Ruoqi Peng, David C. Budd, Matthew C. Lucas, Rama K. Kondru, Ruben Alvarez Sanchez
Publikováno v:
Journal of Medicinal Chemistry. 55:7920-7939
Lysophosphatidic acid is a class of bioactive phospholipid that mediates most of its biological effects through LPA receptors, of which six isoforms have been identified. The recent results from LPA1 knockout mice suggested that blocking LPA1 signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2902548479e1e1e040690c9e871f2659
https://doi.org/10.1021/jm301022v
https://doi.org/10.1021/jm301022v
Publikováno v:
Future Medicinal Chemistry. 3:1623-1634
In 2002, the first long-acting muscarinic antagonist, tiotropium bromide (Spiriva®), was launched as a once-daily bronchodilating agent for the treatment of chronic obstructive pulmonary disease. Since then, there has been intense discovery research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5e7374e4e09bc3130bde77be2df626
https://doi.org/10.4155/fmc.11.127
https://doi.org/10.4155/fmc.11.127