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pro vyhledávání: '"Drake LeFace"'
Autor:
Jason Hall, Stephen Santoro, Aaron Cooper, Natalie Bezman, Jun Feng, Kanika Chawla, Jaspar Williams, John Gagnon, Dina Polyak, Angela Boroughs, Michelle Nguyen, Suchismita Mohanty, Adam Litterman, Jeff Granja, David DeTomaso, Grace Zheng, Jenessa Smith, Drake LeFace, Tarjei Mikkelsen, Susie Jun
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/3de68468bbeb414eb0074915461c96fd
Autor:
Jun Feng, Drake LeFace, Aaron Cooper, Michelle L.T. Nguyen, Suchismita Mohanty, Angela C. Boroughs, Jason F. Hall, Adam J. Litterman, Jenessa B. Smith, Jeff Granja, Dina Polyak, John D. Gagnon, Jaspar Williams, Kanika Chawla, Susie Jun, Stephen Santoro, Tarjei S. Mikkelsen, Grace X.Y. Zheng, Natalie Bezman, David DeTomaso
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundIn solid tumors, CAR T cell efficacy is limited by off-tumor toxicity and suppression by the tumor microenvironment (TME). AB-X is an integrated circuit T cell (ICT cell) intended for the treatment of ovarian cancer. AB-X includes a transge