Identifying CD19-targeted CAR-T cell immune pathways in an in vitro human immune mimetic cytokine release assay.

Autor: Dinh-Le T; Sanofi, Global Human Immunology, Orlando, FL, USA., Escobar J; Sanofi, Global Human Immunology, Orlando, FL, USA., Poisson L; Sanofi, Global Human Immunology, Orlando, FL, USA., Adkins K; Sanofi, Pre-Clinical Safety, Cambridge, MA, USA., Jornet Culubret M; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital Wurzburg, Wurzburg, Germany., Scheller L; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital Wurzburg, Wurzburg, Germany., van den Brulle J; T-CURX GmbH, Würzburg, Germany., Hudecek M; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital Wurzburg, Wurzburg, Germany.; Fraunhofer-Institut für Zelltherapie und Immunologie, Außenstelle Würzburg Zelluläre Immuntherapie, Würzburg, Germany., Drake Iii DR; Sanofi, Global Human Immunology, Orlando, FL, USA., Alb M; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital Wurzburg, Wurzburg, Germany., Luna E; Sanofi, Global Human Immunology, Orlando, FL, USA.

Publikováno v: Journal of immunotoxicology [J Immunotoxicol] 2024 Oct; Vol. 21 (sup1), pp. S29-S37. Date of Electronic Publication: 2024 Dec 10.