Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Drake A. Russell"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Methylation of alkyl thiols is a biotransformation pathway designed to reduce thiol reactivity and potential toxicity, yet the gene and protein responsible for human alkyl thiol methyltransferase (TMT) activity remain unknown. Here we demons
Externí odkaz:
https://doaj.org/article/6dfb2e5090dd4cb1a587933d21f727de
S-Methylation of drugs containing thiol-moieties often alters their activity and results in detoxification. Historically, scientists attributed methylation of exogenous aliphatic and phenolic thiols to a putativeS-adenosyl-L-methionine dependent memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68363ba58ce6b4f665375ff30f0b1923
https://doi.org/10.1101/2022.10.12.511968
https://doi.org/10.1101/2022.10.12.511968
Autor:
Robert W. Robey, Christina M. Fitzsimmons, Wilfried M. Guiblet, William J.E. Frye, José M. González Dalmasy, Li Wang, Drake A. Russell, Lyn M. Huff, Andrew J. Perciaccante, Fatima Ali-Rahmani, Crystal C. Lipsey, Heidi M. Wade, Allison V. Mitchell, Siddhardha S. Maligireddy, David Terrero, Donna Butcher, Elijah F. Edmondson, Lisa M. Jenkins, Tatiana Nikitina, Victor B. Zhurkin, Amit K. Tiwari, Anthony D. Piscopio, Rheem A. Totah, Susan E. Bates, H. Efsun Arda, Michael M. Gottesman, Pedro J. Batista
Histone deacetylase inhibitors (HDACis) are part of a growing class of epigenetic therapies used for the treatment of cancer. While elevated levels of the efflux pump P-gp are associated within vitroresistance to romidepsin, this mechanism does not t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eab6c73a6fa5f6f5baa893e9093b0da
https://doi.org/10.1101/2022.10.07.511310
https://doi.org/10.1101/2022.10.07.511310
Autor:
Drake A Russell, Marvin K Chau, Yuanyuan Shi, Ian N Levasseur, Benjamin J Maldonato, Rheem A Totah
Publikováno v:
Drug Metabolism and Disposition. :DMD-AR
Publikováno v:
Free Radical Biology and Medicine. 159:S32
Autor:
Drake Jr., Russell A.
Publikováno v:
Risk Management (00355593). Apr87, Vol. 34 Issue 4, p64-66. 3p. 1 Black and White Photograph.
Autor:
Drake Jr., Russell A.1
Publikováno v:
Risk Management (00355593). Dec85, Vol. 32 Issue 12, p30-32. 2p.