Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Drake, Laface"'
Autor:
Jin-Hwan Han, Mingmei Cai, Jeffery Grein, Samanthi Perera, Hongmei Wang, Mike Bigler, Roenna Ueda, Thomas W. Rosahl, Elaine Pinheiro, Drake LaFace, Wolfgang Seghezzi, Sybil M. Genther Williams
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/90ad0aa7f0a945a7ba29e26d0d2a5980
Autor:
Jin-Hwan Han, Mingmei Cai, Jeffery Grein, Samanthi Perera, Hongmei Wang, Mike Bigler, Roenna Ueda, Thomas W. Rosahl, Elaine Pinheiro, Drake LaFace, Wolfgang Seghezzi, Sybil M. Genther Williams
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The molecule “T cell immunoreceptor with immunoglobulin and ITIM domain,” or TIGIT, has recently received much attention as a promising target in the treatment of various malignancies. In spite of the quick progression of anti-TIGIT antibodies in
Externí odkaz:
https://doaj.org/article/95ab8cf9ccb34b67a1feb2cd6810ed2c
Autor:
David Bauché, Smita Mauze, Christina Kochel, Jeff Grein, Anandi Sawant, Yulia Zybina, Lakshmanan Annamalai, Jennifer H Yearley, Juha Punnonen, Edward P Bowman, Alissa Chackerian, Drake Laface
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Programmed cell death protein 1 (PD-1) and CTLA4 combination blockade enhances clinical efficacy in melanoma compared with targeting either checkpoint alone; however, clinical response improvement is coupled with increased risk of developi
Externí odkaz:
https://doaj.org/article/1bda0443d10a44cca19b501ab433abcf
Autor:
Thomas W. Rosahl, Mingmei Cai, Jin-Hwan Han, Wolfgang Seghezzi, Jeffery Grein, Elaine M. Pinheiro, M. Bigler, Hongmei Wang, Samanthi A. Perera, Sybil M. G. Williams, Roenna Ueda, Drake LaFace
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92bee687aeef7d106bbd674fa16ded7
https://www.frontiersin.org/articles/10.3389/fimmu.2020.615755/full
https://www.frontiersin.org/articles/10.3389/fimmu.2020.615755/full
Autor:
Juha Punnonen, Lakshmanan Annamalai, Edward P. Bowman, Peng Yang, Drake LaFace, Jennifer H. Yearley, Anandi Sawant, Alissa A. Chackerian, Smita Mauze, Jeff Grein, Wendy M. Blumenschein, David Bauché, Yulia Zybina, Christina Kochel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundProgrammed cell death protein 1 (PD-1) and CTLA4 combination blockade enhances clinical efficacy in melanoma compared with targeting either checkpoint alone; however, clinical response improvement is coupled with increased risk of developin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b844e8ae21e846e989431cbcfc0e697
https://jitc.bmj.com/content/8/2/e001584.full
https://jitc.bmj.com/content/8/2/e001584.full
Autor:
Angela L. Cuenca, Drake LaFace, Philip J. Scarpace, Lori F. Gentile, Matthew J. Delano, Philip O. Scumpia, Dallas N. Joiner, Lyle L. Moldawer, Philip A. Efron, Kindra M. Kelly-Scumpia, Robert D. Winfield, Lizette Vila, Alex G. Cuenca, Michael Matheny
Publikováno v:
The Journal of Immunology. 192:6111-6119
Cancer progression is associated with inflammation, increased metabolic demand, infection, cachexia, and eventually death. Myeloid-derived suppressor cells (MDSCs) commonly expand during cancer and are associated with adaptive immune suppression and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8fa5cc3f665813b3512f72d759ae2e
https://doi.org/10.4049/jimmunol.1302895
https://doi.org/10.4049/jimmunol.1302895
Autor:
Salvatore Santino, Patricia Brown, Thomas P. Roddy, Jason Saunders, Haihong Zhou, Rory J. Rohm, Michele A. Cleary, Maarten Hoek, Zhong Liu, Daniel Blom, Doris F. Cully, Pan Yi, James Conway, Gulesi Ayanoglu, Ablatt Mahsut, Drake LaFace, Dan Shuster, Daniel M. Gorman, Katie Southwick, Ning Ren, Rebecca A. Chmielowski
Publikováno v:
Rapid Communications in Mass Spectrometry. 27:2639-2647
RATIONALE Human genetics studies in African Americans have shown a strong correlation between polymorphisms in the ApoL1 gene and chronic kidney disease (CKD). To gain further insight into the etiology of ApoL1-associated kidney diseases, the determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::777f4bf3e981a0bb5b75a6d5f35453c8
https://doi.org/10.1002/rcm.6734
https://doi.org/10.1002/rcm.6734
Autor:
Gulesi Ayanoglu, Erin Murphy, Scott P. Turner, Amy M Beebe, Ivan H. Chan, John B. Mumm, Venkataraman Sriram, Xueqing Zhang, Catherine Sheppard, Jeff Grein, Beth Basham, Martin Oft, Satya Medicherla, Jan Emmerich, Melanie A. Kleinschek, Lingling Wu, Michael Judo, Steven J. Blaisdell, Terrill K. McClanahan, Susan Cannon-Carlson, John L. Langowski, Danling Gu, Kyu Hong, Wolfgang Seghezzi, Smita Mauze, Brittany C. Paporello, Bela Desai, Saraswathi Naravula, Jie Dai, Drake LaFace, Collette M. Cutler
Publikováno v:
Cancer Cell. 20(6):781-796
Summary Tumor immune surveillance and cancer immunotherapies are thought to depend on the intratumoral infiltration of activated CD8 + T cells. Intratumoral CD8 + T cells are rare and lack activity. IL-10 is thought to contribute to the underlying im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be7a3a8453fea6fe1ae6913680436ca
Autor:
Mary Petro, Chuan-Chu Chou, Cheng-Chi Chao, Nancy E Lane, Drake LaFace, Daniel M. Gorman, Wei Yao, Sarvesh Adda, Edward P. Bowman, Marlowe S. Tessmer, Iannis E. Adamopoulos, Robert H. Pierce
Publikováno v:
The Journal of Immunology. 187:951-959
The role of IL-23 in the development of arthritis and bone metabolism was studied using systemic IL-23 exposure in adult mice via hydrodynamic delivery of IL-23 minicircle DNA in vivo and in mice genetically deficient in IL-23. Systemic IL-23 exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa29b004df03d382bffe99192f40ffd
https://doi.org/10.4049/jimmunol.1003986
https://doi.org/10.4049/jimmunol.1003986
Autor:
Drake LaFace, Nico van Rooijen, Elena Brin, James E. Talmadge, Matthew J. Delano, Todd Machemer, Van Tsai, Manjiri Sathe, Terrill K. McClanahan, Kalyan Pande, Lyle L. Moldawer, Joseph H. Phillips, Roanna Ueda
Publikováno v:
Molecular Therapy, 17(3), 508-515. Nature Publishing Group
Pande, K, Ueda, R, Machemer, T, Sathe, M, Tsai, V, Brin, E, Delano, M J, van Rooijen, N, McClanahan, T K, Talmadge, J E, Moldawer, L L, Phillips, J R & Laface, D M 2009, ' Cancer-induced Expansion and Activation of CD11b(+)Gr-1(+) Cells Predispose Mice to Adenoviral-triggered Anaphylactoid-type Reactions ', Molecular Therapy, vol. 17, no. 3, pp. 508-515 . https://doi.org/10.1038/mt.2008.280
Pande, K, Ueda, R, Machemer, T, Sathe, M, Tsai, V, Brin, E, Delano, M J, van Rooijen, N, McClanahan, T K, Talmadge, J E, Moldawer, L L, Phillips, J R & Laface, D M 2009, ' Cancer-induced Expansion and Activation of CD11b(+)Gr-1(+) Cells Predispose Mice to Adenoviral-triggered Anaphylactoid-type Reactions ', Molecular Therapy, vol. 17, no. 3, pp. 508-515 . https://doi.org/10.1038/mt.2008.280
Intravascular delivery (1.5 x 10(9) particles and higher) of recombinant adenovirus (rAd) induces myeloid cell mediated, self-limiting hemodynamic responses in normal mice. However, we observed anaphylactoid-type reactions and exacerbated hemodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b5cbc77495bbf68c49787c05462abb
https://doi.org/10.1038/mt.2008.280
https://doi.org/10.1038/mt.2008.280