Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Drago Sliskovic"'
Autor:
Danielle Dettling, Jeffrey Asbill, Victor Fedij, Derek Vrieze, David Pocalyko, Wen Song Yue, Radhika Yalamanchili, Drago Sliskovic, Jie Jack Li, Catherine R. Kostlan, Theodore R. Johnson, Lain Yen Hu, Susan Ciotti, Matthew Carroll, Huangshu John Lei, Daniel Du, Brian Samas, Howard Welgus, Kimberly Jane Wade, Kimberly Lapham, Teresa Krieger-Burke, Mark Lovdahl, Conglin Fan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5693-5697
A series of amino-pyridines were synthesized and evaluated for androgen antagonist activities. Among these compounds, (R)-(+)-6-[methyl-(1-phenyl-ethyl)-amino]-4-trifluoromethyl-nicotinonitrile was the most active example of this class. This compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9391a6ce2569dff79df22be42d350230
https://doi.org/10.1016/j.bmcl.2007.07.059
https://doi.org/10.1016/j.bmcl.2007.07.059
Autor:
Drago Sliskovic, Essenburg Ad, Joseph Armand Picard, J. F. Reindel, L. L. Minton, B.R. Krause, R. L. Stanfield, W. H. Roark
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:713-718
The synthesis and structure-activity relationships of a series of malonester amide ACAT inhibitors are described. One of these compounds, 4s , was shown to be a potent inhibitor of both the intestinal and arterial enzymes, bioactive upon oral dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f0d88d43a22709606ea47b4b323690
https://doi.org/10.1016/0960-894x(96)00098-4
https://doi.org/10.1016/0960-894x(96)00098-4
Autor:
Maureen K. Anderson, Patrice Lee, J. F. Reindel, K. L. Hamelehle, R. L. Stanfield, Drago Sliskovic, J. A. Picard, Bruce D. Roth, B.R. Krause, D. Turluck, Andrew D. White, Sandra Bak Mueller, Reynold Homan, Thomas M.A. Bocan, Patrick Michael O'brien, Helen Tsenwhei Lee, Claude Forsey Purchase, R. F. Bousley
Publikováno v:
Journal of Medicinal Chemistry. 39:2354-2366
A series of tetrazole amide derivatives of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide (1) was prepared and evaluated for their ability to inhibit acyl-CoA: cholesterol O-acyltransferase (ACAT) in vitro and to lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50d87ec1d2a4e896eabf54421ba52bd
https://doi.org/10.1021/jm960170f
https://doi.org/10.1021/jm960170f
Publisher Summary This chapter explores that many different clofibrate-type compounds soon appeared with some desirable features, and a unifying molecular mechanism now exists for these drugs, none of them are particularly efficacious with regard to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::365d4835ef9790ca9750b260d25adde7
https://doi.org/10.1016/s0079-6468(08)70070-5
https://doi.org/10.1016/s0079-6468(08)70070-5
Autor:
Bruce Roth, Drago Sliskovic
Publikováno v:
Current Pharmaceutical Design. 7:i-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8935e6a7feb032f428f168fde490c62
https://doi.org/10.2174/1381612013397924
https://doi.org/10.2174/1381612013397924
Autor:
Bruce Roth, Drago Sliskovic
Publikováno v:
Current Pharmaceutical Design. 7:i-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26d0eeedcf203b77e65caa93c92615b6
https://doi.org/10.2174/1381612013398149
https://doi.org/10.2174/1381612013398149