Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Dragana Cado"'
Autor:
Heather Melichar, Ou Li, Jenny Ross, Hilary Haber, Dragana Cado, Hector Nolla, Ellen A Robey, Astar Winoto
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19854 (2011)
Directed differentiation of human embryonic stem cells (hESCs) into any desired cell type has been hailed as a therapeutic promise to cure many human diseases. However, substantial roadblocks still exist for in vitro differentiation of hESCs into dis
Externí odkaz:
https://doaj.org/article/bc2b318e34d84e0d8b623bda43341e43
Publikováno v:
The Journal of Experimental Medicine
Complete IgHC gene rearrangement occurs only in B cells in a stage-specific and ordered manner. We used gene targeting to reposition a distal VH gene segment to a region just 5′ of the DH gene cluster and found its activation to be highly dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e118a2fa920009b9e1a80b97ef47193
http://europepmc.org/articles/PMC2150984
http://europepmc.org/articles/PMC2150984
Autor:
Gretchen E. Diehl, Herman H. Yue, Kristina Hsieh, Anna A. Kuang, Mary Ho, Lisa A. Morici, Laurel L. Lenz, Dragana Cado, Lee W. Riley, Astar Winoto
Publikováno v:
Immunity. 21:877-889
TRAIL receptor (TRAIL-R) signaling has been implicated in inducing apoptosis in tumor cells, but little is understood about its physiological function. Here, we report the generation and characterization of TRAIL-R(-/-) mice, which develop normal lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35efde16b3dfe1bff9cbd02d0bd5b61d
https://doi.org/10.1016/j.immuni.2004.11.008
https://doi.org/10.1016/j.immuni.2004.11.008
Publikováno v:
Cell. 118(1):19-29
Regulated gene rearrangement is thought to underlie allelic exclusion, the observation that an individual B cell expresses only a single immunoglobulin molecule. Previous data has implicated transcriptional activation of rearranging loci in the regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec9b42ca71e055f26e9344c0647480b
Publikováno v:
Journal of Biological Chemistry. 278:47104-47109
Nur77 and its family members, Nor-1 and Nurr1, are orphan steroid receptors implicated in a wide variety of biological processes, including apoptosis and dopamine neuron agenesis. Expression of these family members can be detected at low levels in ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1db2067db8187cf4233f9ddee8a698
https://doi.org/10.1074/jbc.m307496200
https://doi.org/10.1074/jbc.m307496200
Publikováno v:
Immunity. 18(4):513-521
FADD is an adaptor known to transmit apoptotic signals from members of the tumor necrosis factor receptor family. We show here that FADD has a domain implicated in cell proliferation. Mice bearing the Asp mutation in the serine 191 phosphorylation si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b9c79901fafc5d5e63d0d728a82670
Publikováno v:
Journal of Biological Chemistry. 277:43344-43351
During angiogenesis, endothelial cells undergo proliferation, reorganization, and stabilization to establish a mature vascular network. This process is critical for establishing a functional circulatory system during development and contributes to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a47b7d20fce493cbc783749b46b1c74
https://doi.org/10.1074/jbc.m207573200
https://doi.org/10.1074/jbc.m207573200
Publikováno v:
Proceedings of the National Academy of Sciences. 99:868-873
Natural killer (NK) cells are believed to achieve self-tolerance through the expression of self-MHC-specific inhibitory receptors, such as members of the Ly49 and CD94/NKG2 families. IndividualLy49genes are stochastically expressed by NK subsets and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a6c96d065690535258336734358516
https://doi.org/10.1073/pnas.022500599
https://doi.org/10.1073/pnas.022500599
Publikováno v:
European Journal of Immunology. 30:920-930
Using a new mAb, 2F1, we characterize a mouse natural killer (NK) cell antigen termed 'killer cell lectin-like receptor G1' (KLRG1; formerly mouse MAFA or 2F1-Ag). KLRG1 is expressed on 30-60% of murine NK cells, and a small fraction of T cells, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa981896a9b69d5d16898d46e782f7b
https://doi.org/10.1002/1521-4141(200003)30:3<920::aid-immu920>3.0.co
https://doi.org/10.1002/1521-4141(200003)30:3<920::aid-immu920>3.0.co
Publikováno v:
The Journal of Immunology. 163:5312-5318
During thymic development the recognition of MHC proteins by developing thymocytes influences their lineage commitment, such that recognition of class I MHC leads to CD8 T cell development, whereas recognition of class II MHC leads to CD4 T cell deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3216d7978f126c08790716bd23f06917
https://doi.org/10.4049/jimmunol.163.10.5312
https://doi.org/10.4049/jimmunol.163.10.5312