Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dragan A, Cirovic"'
Autor:
G. Sitta Sittampalam, Robert P. Hertzberg, William P. Janzen, Dragan A. Cirovic, Ricardo Macarron, David J. Burns, Tina Garyantes, Martyn Banks, Darren V. S. Green, Jeff W. Paslay, Dejan Bojanic, Ulrich Schopfer
Publikováno v:
Nature Reviews Drug Discovery. 10:188-195
High-throughput screening (HTS) has been postulated in several quarters to be a contributory factor to the decline in productivity in the pharmaceutical industry. Moreover, it has been blamed for stifling the creativity that drug discovery demands. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0f5fd05d9f368f1dc535c4360ed993
https://doi.org/10.1038/nrd3368
https://doi.org/10.1038/nrd3368
Autor:
David Stefany, Ali Ardati, Harris Keith John, Aguiar Joacy C, Roy J. Vaz, Ashfaq Parkar, Lim Sungtaek, Yi Li, Tim Gillespy, Gardner Charles J, Lan Mu, Robert Marcus, Cao Bin, Isabelle Morize, Dragan A. Cirovic
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:66-75
A Comparative Molecular Similarity Indices Analysis (CoMSIA) was performed for 2,6-substituted-4-monosubstituted aminopyrimidine antagonists of prostaglandin D(2) receptor (DP). Both two-component (Q(2) = 0.63, R(2) = 0.82, SEE = 0.47 pIC(50)) and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f058aca40eaf9b900d4d5215c9a19b
https://doi.org/10.1016/j.bmcl.2010.11.071
https://doi.org/10.1016/j.bmcl.2010.11.071
Autor:
Dragan A. Cirovic
Publikováno v:
Talanta. 45:989-1000
This work describes a simulation study aimed at establishing the impact of mixture design on the prediction ability of PLS regression models. Data sets are formed by multiplying UV absorbance spectra of 12 PAHs by their concentration profiles. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec117f6eb480703d31d47667317d99f2
https://doi.org/10.1016/s0039-9140(97)00205-1
https://doi.org/10.1016/s0039-9140(97)00205-1
Autor:
Dragan A. Cirovic
Publikováno v:
TrAC Trends in Analytical Chemistry. 16:148-155
Applications of multi-layer feed-forward artificial neural networks (ANN) to spectroscopy are reviewed. Network architecture and training algorithms are discussed. Back-propagation, the most commonly used training algorithm, is analyzed in greater de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b56b123125c210de283c38463955985
https://doi.org/10.1016/s0165-9936(97)00007-1
https://doi.org/10.1016/s0165-9936(97)00007-1
Autor:
Ricardo, Macarron, Martyn N, Banks, Dejan, Bojanic, David J, Burns, Dragan A, Cirovic, Tina, Garyantes, Darren V S, Green, Robert P, Hertzberg, William P, Janzen, Jeff W, Paslay, Ulrich, Schopfer, G Sitta, Sittampalam
Publikováno v:
Nature reviews. Drug discovery. 10(3)
High-throughput screening (HTS) has been postulated in several quarters to be a contributory factor to the decline in productivity in the pharmaceutical industry. Moreover, it has been blamed for stifling the creativity that drug discovery demands. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c3fccc1e84f7da4f88b80412cdddcb4
https://pubmed.ncbi.nlm.nih.gov/21358738
https://pubmed.ncbi.nlm.nih.gov/21358738
Autor:
Dejan Pavlovic, Ana Mitrović, Dragan M. Cirovic, Svetlana Dragojevic-Dikic, Branka Nikolic, Relja Lukic
Publikováno v:
The AustralianNew Zealand journal of obstetricsgynaecology. 44(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1db5ccc885a6b80c1147e0f759ab956
https://pubmed.ncbi.nlm.nih.gov/15191454
https://pubmed.ncbi.nlm.nih.gov/15191454
Publikováno v:
The Analyst. 121:575
Samples of air taken from a high temperature coke oven plant were assayed for the concentration of PAHs. The analyses were focused on a group of 16 PAHs as recommended by US Environmental Protection Agency. Their electronic absorption spectra and GC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49390021387e60297767579ab9cca9b3
https://doi.org/10.1039/an9962100575
https://doi.org/10.1039/an9962100575
Publikováno v:
Analytical Communications. 33:231
The instrumental noise distribution in electronic absorption spectrometry was studied by recording 27 instrumental replicates at five concentration levels of a series of dilutions of pyrimidine. It was found that the dependence of noise on concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8ddc7c01623f949d0ee59d1e12d6eb
https://doi.org/10.1039/ac9963300231
https://doi.org/10.1039/ac9963300231
Publikováno v:
The Analyst. 121:581
Partial least squares (PLS) calibration has been applied in the study of electronic absorption spectra of pure chlorophyll a. Inverse univariate calibration was applied separately at each wavelength. The effectiveness of the calibration models was qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66a62fdc9951e6cb5288611e8d584199
https://doi.org/10.1039/an9962100581
https://doi.org/10.1039/an9962100581